Marie-Anne Debily

发表

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

P. Varlet, N. Boddaert, S. Puget, 2015, Acta Neuropathologica.

Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Ranadip Pal, Charles Keller, Nathalene Truffaux, 2015, Nature Medicine.

Functionally-defined Therapeutic Targets in Diffuse Intrinsic Pontine Glioma

Nicholas J. Wang, Noah E. Berlow, Matthew N. Svalina, 2015, Nature Medicine.

EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression

P. Varlet, F. Andreiuolo, J. Grill, 2020, Acta neuropathologica communications.

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

Kun Mu, Stefan M. Pfister, Sergey Popov, 2017, Cancer cell.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Kanako O. Koyanagi, Michael A. Thomas, Sandro J. de Souza, 2004, PLoS Biology.

A Functional and Regulatory Network Associated with PIP Expression in Human Breast Cancer

Charles Auffray, Sandrine Imbeaud, Marie-Anne Debily, 2009, PloS one.

Correction: Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Kanako O. Koyanagi, Michael A. Thomas, Gopal R. Gopinath, 2004, PLoS biology.

Large Scale RNAi Screen Reveals That the Inhibitor of DNA Binding 2 (ID2) Protein Is Repressed by p53 Family Member p63 and Functions in Human Keratinocyte Differentiation*

X. Gidrol, R. Mantovani, P. Romeo, 2011, The Journal of Biological Chemistry.

Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location

David T. W. Jones, S. Pfister, P. Varlet, 2018, Acta Neuropathologica Communications.

The dark matter of diffuse intrinsic pontine gliomas: an update

P. Varlet, S. Puget, J. Grill, 2019, Expert Opinion on Orphan Drugs.

Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging

M. Kool, S. Pfister, P. Varlet, 2018, Brain pathology.

VRK3 depletion induces cell cycle arrest and metabolic reprogramming of pontine diffuse midline glioma - H3K27 altered cells

L. Le Dret, T. Blauwblomme, D. Castel, 2023, Frontiers in Oncology.

VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells

J. Grill, M. Debily, E. Oberlin, 2023, bioRxiv.

Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation

David T. W. Jones, S. Pfister, P. Varlet, 2020, Acta Neuropathologica.

A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival

S. Puget, J. Grill, M. Debily, 2019, Oncogene.

TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG)

P. Varlet, N. Boddaert, S. Puget, 2019, Clinical Cancer Research.

Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer.

A. Camarca, M. Debily, D. Piatier‐Tonneau, 2003, Human molecular genetics.

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I.

A. Bernheim, M. Debily, D. Piatier‐Tonneau, 2002, Human molecular genetics.

Cell microarrays in drug discovery.

Xavier Gidrol, David Castel, Marie-Anne Debily, 2006, Drug discovery today.

Copy-number alterations reshape the classification of diffuse intrinsic pontine gliomas. First exome sequencing results of the BIOMEDE trial.

K. Blomgren, P. Varlet, S. Puget, 2021, medRxiv.

Cancer Cell Integrated molecular meta-analysis of 1000 paediatric high grade and diffuse intrinsic pontine glioma

R. Verhaak, M. Monje, J. Mora, 2017 .

Glioma oncogenesis in the Constitutional mismatch repair deficiency (CMMRD) syndrome

S. Puget, F. Andreiuolo, L. Guerrini-Rousseau, 2024, Neuro-oncology advances.

High-grade gliomas in adolescents and young adults highlight histomolecular differences with their adult and paediatric counterparts.

E. Mandonnet, M. Sanson, P. Varlet, 2020, Neuro-oncology.

New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis.

S. Mériaux, P. Varlet, F. Geffroy, 2017, Oncotarget.

Diffuse intrinsic pontine gliomas (DIPG) at recurrence: is there a window to test new therapies in some patients?

P. Varlet, N. Boddaert, S. Puget, 2018, Journal of Neuro-Oncology.

Radiogenomics of diffuse intrinsic pontine gliomas (DIPGs): correlation of histological and biological characteristics with multimodal MRI features

M. Zilbovicius, P. Varlet, N. Boddaert, 2021, European Radiology.

Cerebral blood flow changes after radiation therapy identifies pseudoprogression in diffuse intrinsic pontine gliomas

M. Zilbovicius, P. Varlet, N. Boddaert, 2018, Neuro-oncology.

An integrative radiological, histopathological and molecular analysis of pediatric pontine histone-wildtype glioma with MYCN amplification (HGG-MYCN)

K. Blomgren, P. Varlet, N. Boddaert, 2019, Acta Neuropathologica Communications.

A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells

David S. Lapointe, Claude Gazin, Michael R. Green, 2012, PLoS genetics.

The pediatric supratentorial MYCN-amplified high-grade gliomas methylation class presents the same radiological, histopathological and molecular features as their pontine counterparts

P. Varlet, N. Boddaert, S. Puget, 2020, Acta Neuropathologica Communications.