Chloe A L Thompson-Peach

Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability

A. Reinisch, R. Majeti, Manhong Wu, 2022, Cancer discovery.

Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia

Anna L. Brown, Mahmoud A. Bassal, U. Roessner, 2022, Nature Communications.

Targeting human CALR‐mutated MPN progenitors with a neoepitope‐directed monoclonal antibody

A. Reinisch, M. Dottore, Angel F. Lopez, 2022, EMBO reports.

A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure

Sharad Kumar, S. Gronthos, S. Paton, 2022, Leukemia.

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

G. Goodall, A. Bert, R. D'Andrea, 2022, Blood.