F. Carroll

发表

Structure of the human k-opioid receptor in complex with JDTic

R. Stevens, Xi-Ping Huang, B. Roth, 2012 .

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists.

H. Navarro, F. Carroll, M. Damaj, 2010, Journal of natural products.

Pharmacotherapies for treatment of cocaine abuse: preclinical aspects.

M. Kuhar, F. Carroll, L. Howell, 1999, Journal of medicinal chemistry.

Bupropion and bupropion analogs as treatments for CNS disorders.

R. Lukas, S. Mascarella, H. Navarro, 2014, Advances in pharmacology.

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction.

H. Navarro, F. Carroll, B. Blough, 2009, Journal of medicinal chemistry.

Identification of the first trans-(3R,4R)- dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activity.

F I Carroll, S W Mascarella, James B. Thomas, 2001, Journal of medicinal chemistry.

Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.

F I Carroll, P Abraham, S W Mascarella, 1994, Journal of medicinal chemistry.

Designer drugs: a medicinal chemistry perspective (II)

S. Mascarella, F. Carroll, A. Lewin, 2020, Annals of the New York Academy of Sciences.

Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter.

H. Navarro, F. Carroll, Chunyang Jin, 2008, Journal of medicinal chemistry.

Synthesis and monoamine transporter binding properties of 2beta-[3'-(substituted benzyl)isoxazol-5-yl]- and 2beta-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3beta-(substituted phenyl)tropanes.

H. Navarro, F. Carroll, Chunyang Jin, 2008, Bioorganic & medicinal chemistry.

Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.

J. L. Howard, M. Kuhar, G. T. Pollard, 2004, Journal of medicinal chemistry.

Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: Preliminary evidence for different binding domains

K. Rice, F. Carroll, R. Rothman, 1994, Neurochemical Research.

Highly potent cocaine analogs cause long-lasting increases in locomotor activity.

M. Kuhar, F. Carroll, T. Kopajtic, 1996, European journal of pharmacology.

Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues.

L. Brieaddy, H. Navarro, F. Carroll, 2005, Journal of medicinal chemistry.

Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3 R)-7-Hydroxy- N-[(1 S)-2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic).

T. Fennell, R. Snyder, James B. Thomas, 2018, Journal of medicinal chemistry.

Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3 R)- N-[1 R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic).

T. Fennell, R. Snyder, James B. Thomas, 2018, Journal of medicinal chemistry.

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres.

James B. Thomas, S. Runyon, C. Kormos, 2016, Bioorganic & medicinal chemistry.

Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation.

R. Lukas, S. Mascarella, H. Navarro, 2010, Journal of medicinal chemistry.

Synthesis And Characterization Of In Vitro And In Vivo Profiles Of Synthesis And Characterization Of In Vitro And In Vivo Profiles Of Hydroxybupropion Analogues: Aids To Smoking Cessation Hydroxybupropion Analogues: Aids To Smoking Cessation

S. Mascarella, M. Damaj, S. Marxer-Miller, 2022 .

Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2β-substituted tropanes.

R. Lukas, S. Mascarella, H. Navarro, 2010, Journal of medicinal chemistry.

Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.

F I Carroll, P Abraham, M. Kuhar, 1991, Journal of medicinal chemistry.

RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro

M. Kuhar, M. Reith, F. Carroll, 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.