Yan Xiong

Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer’s disease proteopathology for precision medication

Chongchong Xu, Yadong Li, Yanjia Luo, 2023, Research square.

Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.

U. Oppermann, M. Vedadi, C. Johansson, 2024, Journal of medicinal chemistry.

A Chemical Probe For Tudor Domain Protein Spin1 to Investigate Chromatin Functions

O. Fedorov, C. Bountra, C. Arrowsmith, 2019 .

Targeting G9a translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalae

Xuping Xie, Xufen Yu, Feng Zhang, 2024, bioRxiv.

Discovery of the First-in-Class G9a/GLP PROTAC Degrader.

H. Kaniskan, Jian Jin, Yulin Han, 2024, Journal of medicinal chemistry.

USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice

Fabin Dang, Wenyi Wei, A. Rezaeian, 2023, Science Translational Medicine.

Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader.

Jian Jin, Lihuai Qin, Yan Xiong, 2024, Journal of medicinal chemistry.