J. Aceña

发表

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas.

Hong Liu, Yu Zhou, Jiang Wang, 2016, Chemical Reviews.

Total synthesis of (+)-7-deoxypancratistatin from furan.

J. L. Aceña, O. Arjona, M. León, 2000, Organic letters.

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Hong Liu, Jiang Wang, C. del Pozo, 2014, Chemical reviews.

Asymmetric Mannich reaction between (S)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine and malonic acid derivatives. Stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids.

V. Soloshonok, Etsuko Tokunaga, N. Shibata, 2014, Organic & biomolecular chemistry.

Stereoselective access to fluorinated and non-fluorinated quaternary piperidines: synthesis of pipecolic acid and iminosugar derivatives.

J. L. Aceña, S. Fustero, Javier Miró, 2012, Chemistry.

Diastereoselective intramolecular additions of allyl- and propargylsilanes to iminium ions: synthesis of cyclic and bicyclic quaternary amino acids.

J. L. Aceña, S. Fustero, N. Mateu, 2010, Organic letters.

Recent advances in the trifluoromethylation methodology and new CF3-containing drugs

Hong Liu, Jiang Wang, V. Soloshonok, 2014 .

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation.

I. Paterson, M. J. Coster, J. L. Aceña, 2005, Organic & biomolecular chemistry.

An efficient entry to optically active anti- and syn-beta-amino-alpha-trifluoromethyl alcohols.

S. Fustero, A. Asensio, J. F. Sanz-Cervera, 2008, Organic Letters.

Organocatalytic anti‐Selective Mannich Reactions with Fluorinated Aldimines: Synthesis of anti‐γ‐Fluoroalkyl‐γ‐amino Alcohols

J. L. Aceña, S. Fustero, J. F. Sanz-Cervera, 2009 .

An Efficient Entry to Optically Active anti‐ and syn‐β‐Amino‐α‐trifluoromethyl Alcohols.

S. Fustero, A. Asensio, J. F. Sanz-Cervera, 2008 .

The self-disproportionation of the enantiomers (SDE) of methyl n-pentyl sulfoxide via achiral, gravity-driven column chromatography: a case study.

K. Klika, V. Soloshonok, J. Drabowicz, 2014, Organic & biomolecular chemistry.

FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF‐1α activation

L. Rodríguez-Mañas, E. López-Hernández, J. Sánchez-Puelles, 2015, British journal of pharmacology.

Optical purifications via self-disproportionation of enantiomers by achiral chromatography: case study of a series of α-CF3-containing secondary alcohols.

Alicja Wzorek, Taizo Ono, V. Soloshonok, 2013, Chirality.

Self-Disproportionation of Enantiomers of Chiral, Non-Racemic Fluoroorganic Compounds: Role of Fluorine as Enabling Element

Vadim A. Soloshonok, Alexander E. Sorochinsky, V. Soloshonok, 2012 .

Unconventional preparation of racemic crystals of isopropyl 3,3,3-trifluoro-2-hydroxypropanoate and their unusual crystallographic structure: the ultimate preference for homochiral intermolecular interactions.

V. Soloshonok, José Luis Aceña, Vadim A Soloshonok, 2013, Chemical communications.

Inexpensive chemical method for preparation of enantiomerically pure phenylalanine

I. Ojima, H. Moriwaki, V. Soloshonok, 2014, Amino Acids.

Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation

J. Carbonell, A. Granell, J. Rambla, 2014, Front. Plant Sci..

Tiratricol Neutralizes Bacterial Endotoxins and Reduces Lipopolysaccharide‐Induced TNF‐α Production in the Cell

E. Pérez-Payá, F. Albericio, J. L. Aceña, 2008, Chemical biology & drug design.

Tailor-Made α-Amino Acids in the Pharmaceutical Industry: Synthetic Approaches to (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic Acid (Vinyl-ACCA)

Hong Liu, V. Soloshonok, J. L. Aceña, 2016 .

Recent Progress in the in situ Detrifluoroacetylative Generation of Fluoro Enolates and Their Reactions with Electrophiles

Haibo Mei, Jianlin Han, V. Soloshonok, 2015 .

Recent Progress in the in situ Detrifluoroacetylative Generation of Fluoro Enolates and Their Reactions with Electrophiles

G. Röschenthaler, Haibo Mei, Jianlin Han, 2015 .

Asymmetric Carbon–Carbon Bond Formation under Solventless Conditions in Ball Mills

Carsten Bolm, Vadim A. Soloshonok, C. Bolm, 2015 .

Introducing a new radical trifluoromethylation reagent.

Jianlin Han, V. Soloshonok, J. L. Aceña, 2015, Chemical communications.

Synthesis of (2S,3S)-β-(trifluoromethyl)-α,β-diamino acid by Mannich addition of glycine Schiff base Ni(II) complexes to N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimine

G. Röschenthaler, H. Moriwaki, V. Soloshonok, 2015 .

Chemical dynamic kinetic resolution and S/R interconversion of unprotected α-amino acids.

Hong Liu, H. Moriwaki, V. Soloshonok, 2014, Angewandte Chemie.

Design and synthesis of (S)- and (R)-α-(phenyl)ethylamine-derived NH-type ligands and their application for the chemical resolution of α-amino acids.

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2014, Organic & biomolecular chemistry.

Chemical kinetic resolution of unprotected β-substituted β-amino acids using recyclable chiral ligands.

Hong Liu, Shengbin Zhou, Jiang Wang, 2014, Angewandte Chemie.

Asymmetric Synthesis of α‐Amino Acids under Operationally Convenient Conditions

Hong Liu, C. Bolm, V. Soloshonok, 2014 .

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations

V. Soloshonok, J. L. Aceña, A. Sorochinsky, 2014, Amino Acids.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 2: Aldol, Mannich addition reactions, deracemization and (S) to (R) interconversion of α-amino acids

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Amino Acids.

Chemical deracemization and (S) to (R) interconversion of some fluorine-containing α-amino acids

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013 .

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases; Part 1: alkyl halide alkylations

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Amino Acids.

Chemical approach for interconversion of (S)- and (R)-α-amino acids.

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Organic & biomolecular chemistry.

Synthesis of bis-α,α'-amino acids through diastereoselective bis-alkylations of chiral Ni(II)-complexes of glycine.

Hong Liu, Jiang Wang, H. Moriwaki, 2013, Organic & biomolecular chemistry.

Recent Advances in the Asymmetric Synthesis of α‐(Trifluoromethyl)‐Containing α‐Amino Acids

V. Soloshonok, J. L. Aceña, A. Sorochinsky, 2012 .

Synthesis of Fluorinated β-AminoAcids

K. Mikami, V. Soloshonok, María Sánchez-Roselló, 2011 .

Small‐Molecule Therapeutics for Ebola Virus (EBOV) Disease Treatment

Hong Liu, Jiang Wang, V. Soloshonok, 2016 .

Asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by sequential SN2–SN2′ dialkylation of (R)-N-(benzyl)proline-derived glycine Schiff base Ni(II) complex

Haibo Mei, H. Moriwaki, Jianlin Han, 2015 .

A comprehensive examination of the self-disproportionation of enantiomers (SDE) of chiral amides via achiral, laboratory-routine, gravity-driven column chromatography

Yuya Suzuki, K. Klika, Jianlin Han, 2015 .

First Fluorous Synthesis of Fluorinated Uracils

C. Pozo, J. L. Aceña, S. Fustero, 2006 .