Brett A Tounge

Hit triage using efficiency indices after screening of compound libraries in drug discovery.

Allen B Reitz, Garry R Smith, Brett A Tounge, 2009, Current topics in medicinal chemistry.

A Web-based chemoinformatics system for drug discovery.

Brett A Tounge, Scott D Bembenek, Steven J Coats, 2004, Methods in molecular biology.

Linear interaction energy models for beta-secretase (BACE) inhibitors: Role of van der Waals, electrostatic, and continuum-solvation terms.

Allen B Reitz, Brett A Tounge, Charles H Reynolds, 2006, Journal of molecular graphics & modelling.

2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.

Junya Qu, Allen B Reitz, Brett A Tounge, 2007, Journal of medicinal chemistry.

Ligand efficiency and fragment-based drug discovery.

Brett A Tounge, Charles H Reynolds, Scott D Bembenek, 2009, Drug discovery today.

The role of molecular size in ligand efficiency.

Brett A Tounge, Charles H Reynolds, Scott D Bembenek, 2007, Bioorganic & medicinal chemistry letters.