Hinrich W. H. Göhlmann

发表

Translation of disease associated gene signatures across tissues

Adetayo Kasim, Ziv Shkedy, Dan Lin, 2015, Int. J. Data Min. Bioinform..

IsoGene: An R Package for Analyzing Dose-response Studies in Microarray Experiments

Ziv Shkedy, Dan Lin, Hinrich W. H. Göhlmann, 2010, R J..

FABIA: factor analysis for bicluster acquisition

Ulrich Bodenhofer, Adetayo Kasim, Ziv Shkedy, 2010, Bioinform..

Computational Methods Aiding Early-Stage Drug Design (Dagstuhl Seminar 13212)

Andreas Bender, Ziv Shkedy, Hinrich W. H. Göhlmann, 2013, Dagstuhl Reports.

Hinrich W. H. Göhlmann, Willem Talloen, Marijke Van Moerbeke, 2016, J. Bioinform. Comput. Biol..

Information theory based marker evaluation

Dan Lin, Ziv Shkedy, Hinrich W. H. Göhlmann, 2008 .

Spectral Map Analysis of Microarray Data

Hinrich W. H. Göhlmann, Luc Bijnens, Willem Talloen, 2009 .

Increasing the discovery power of -omics studies

Hinrich W. H. Göhlmann, Willem Talloen, Andreas Mayr, 2013 .

beadarrayFilter: An R Package to Filter

Geert Verbeke, Adetayo Kasim, Ziv Shkedy, 2013 .

A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays

Adetayo Kasim, Ziv Shkedy, Hinrich W. H. Göhlmann, 2017, BMC Bioinformatics.

Translating Gene Signatures Across Tissues: A Statistical View

Adetayo Kasim, Ziv Shkedy, Dan Lin, 2010, International Conference on Bioinformatics & Computational Biology.

Classification of Trends in Dose-Response Microarray Experiments Using Information Theory Selection Methods~!2009-02-24~!2009-07-09~!2009-12-23~!

Dan Lin, Ziv Shkedy, Hinrich W. H. Göhlmann, 2009 .

Rejoinder to Use of Principal Component Analysis and the GE ‐Biplot for the Graphical Exploration of Gene Expression Data

Geert Molenberghs, Hinrich W. H. Göhlmann, Luc Bijnens, 2005 .

Data analysis preparation

Hinrich W. H. Göhlmann, Willem Talloen, 2009 .

High-Dimensional Biomarkers in Drug Discovery: The QSTAR Framework

Adetayo Kasim, Ziv Shkedy, Hinrich W. H. Göhlmann, 2016 .

Comparison of methods for the selection of genomic biomarkers

Geert Molenberghs, Abel Tilahun, Ziv Shkedy, 2013, Int. J. Data Min. Bioinform..

Gene Expression Studies Using Affymetrix Microarrays

Hinrich W. H. Göhlmann, Willem Talloen, W. Talloen, 2009, Chapman and Hall / CRC mathematical and computational biology series.

beadarrayFilter: An R Package to Filter Beads

Geert Verbeke, Adetayo Kasim, Ziv Shkedy, 2013, R J..

The high-level similarity of some disparate gene expression measures

Hinrich W. H. Göhlmann, Willem Talloen, Nandini Raghavan, 2007, Bioinform..

I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data

Hinrich W. H. Göhlmann, Luc Bijnens, Willem Talloen, 2007, Bioinform..

FABIA: factor analysis for bicluster acquisition

Ulrich Bodenhofer, Adetayo Kasim, Ziv Shkedy, 2010 .

Understanding drugs in breast cancer through drug sensitivity screening

Hinrich W. H. Göhlmann, John W. M. Martens, John A. Foekens, 2015, SpringerPlus.

Genomic Biomarkers for a Binary Clinical Outcome in Early Drug Development Microarray Experiments

Ziv Shkedy, Hinrich W. H. Göhlmann, Luc Bijnens, 2012, Journal of biopharmaceutical statistics.

Significance Analysis of Dose-Response Microarray Data

Ziv Shkedy, Hinrich W. H. Göhlmann, Luc Bijnens, 2012 .

Dose–Response Modeling Under Simple Order Restrictions Using Bayesian Variable Selection Methods

Adetayo Kasim, Ziv Shkedy, Hinrich W. H. Göhlmann, 2014 .

Functional Genomic Dose-Response Experiments

Hinrich W. H. Göhlmann, Luc Bijnens, Willem Talloen, 2012 .

Genome‐wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays

Hinrich W. H. Göhlmann, Willem Talloen, Tobias Verbeke, 2008, Genes, chromosomes & cancer.

Exploiting the Japanese Toxicogenomics Project for Predictive Modelling of Drug Toxicity

Hinrich W. H. Göhlmann, S. Hochreiter, Djork-Arné Clevert, 2012 .

Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis*

Hinrich W. H. Göhlmann, H. Göhlmann, K. Andries, 2008, Journal of Biological Chemistry.

Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice

Hinrich W. H. Göhlmann, R. D'Hooge, M. Crauwels, 2017, Experimental Neurology.

Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout

Hinrich W. H. Göhlmann, W. Talloen, M. Versele, 2009, Molecular Cancer Therapeutics.

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines

Hinrich W. H. Göhlmann, Jean-Marc Neefs, Yolanda T. Chong, 2020, Scientific Reports.

Transcriptional Response to Corticotropin-Releasing Factor in AtT-20 Cells

Hinrich W. H. Göhlmann, Luc Bijnens, Thomas Steckler, 2004, Molecular Pharmacology.

A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis

Hinrich W. H. Göhlmann, Philip Timmerman, Jean-Marc Neefs, 2005, Science.

Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome.

Hinrich W. H. Göhlmann, M. Camilleri, W. Talloen, 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Alterations in expression of p11 and SERT in mucosal biopsy specimens of patients with irritable bowel syndrome.

Hinrich W. H. Göhlmann, M. Camilleri, H. Göhlmann, 2007, Gastroenterology.

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.

Hinrich W. H. Göhlmann, Aakash Chavan Ravindranath, A. Bender, 2015, Molecular bioSystems.

Transcriptional Characterization of Compounds: Lessons Learned from the Public LINCS Data.

Hinrich W. H. Göhlmann, Heather Turner, Hans De Wolf, 2016, Assay and drug development technologies.

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

Hinrich W. H. Göhlmann, J. Neefs, H. Göhlmann, 2014, Nature Communications.

Molecular profiling of murine sensory neurons in the nodose and dorsal root ganglia labeled from the peritoneal cavity.

Hinrich W. H. Göhlmann, Jeroen Aerssens, Bernard Coulie, 2006, Physiological genomics.

Alterations in the brain-gut axis underlying visceral chemosensitivity in Nippostrongylus brasiliensis-infected mice.

Hinrich W. H. Göhlmann, R. Stead, H. Göhlmann, 2007, Gastroenterology.

Genomic Biomarkers for Depression: Feature-Specific and Joint Biomarkers

Hinrich W. H. Göhlmann, G. Molenberghs, Z. Shkedy, 2010 .

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Hinrich W. H. Göhlmann, David R. Damerell, J. Knight, 2019, Nature Genetics.

Addressing Genotoxicity Risk in Lead Optimization: A PDE10A Inhibitor Case Study

Hinrich W. H. Göhlmann, Bie M. P. Verbist, H. Göhlmann, 2018, Early Drug Development.

Cloning of a second gene encoding 6‐phosphofructo‐2‐kinase in yeast, and characterization of mutant strains without fructose‐2,6‐bisphosphate

Hinrich W. H. Göhlmann, F. Zimmermann, H. Göhlmann, 1996, Molecular microbiology.

Informative or Noninformative Calls for Gene Expression: A Latent Variable Approach

Adetayo Kasim, Ziv Shkedy, Hinrich W. H. Göhlmann, 2010, Statistical applications in genetics and molecular biology.

Pharmaceutical R&D

Hinrich W. H. Göhlmann, W. Talloen, H. Göhlmann, 2009 .

I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data

Hinrich W. H. Göhlmann, Djork-Arné Clevert, W. Talloen, 2007, Bioinform..

Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures.

Hinrich W. H. Göhlmann, H. Göhlmann, R. Herrmann, 2003, Nucleic acids research.

An Investigation on Performance of Significance Analysis of Microarray (SAM) for the Comparisons of Several Treatments with one Control in the Presence of Small‐variance Genes

Hinrich W. H. Göhlmann, T. Burzykowski, T. Geerts, 2008, Biometrical journal. Biometrische Zeitschrift.

Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project.

Hinrich W. H. Göhlmann, Bie M. P. Verbist, A. Bender, 2015, Drug discovery today.

Filtering data from high-throughput experiments based on measurement reliability

Adetayo Kasim, Ziv Shkedy, Hinrich W. H. Göhlmann, 2010, Proceedings of the National Academy of Sciences.