Jizhong Lou

发表

Optimized sgRNA design by deep learning to balance the off-target effects and on-target activity of CRISPR/Cas9

Jie Lan, Yang Cui, Xiaowen Wang, 2020, bioRxiv.

Author Correction: Mechanosensing through immunoreceptors

Jizhong Lou, Wei Chen, William Rittase, 2019, Nature Immunology.

The initiation, propagation and dynamics of CRISPR-SpyCas9 R-loop complex

Hui Chen, Guangtao Song, Jizhong Lou, 2017, Nucleic acids research.

A structure-based sliding-rebinding mechanism for catch bonds.

Jizhong Lou, Cheng Zhu, J. Lou, 2007, Biophysical journal.

Flow induces loop-to-β-hairpin transition on the β-switch of platelet glycoprotein Ibα

Jizhong Lou, Cheng Zhu, J. Lou, 2008, Proceedings of the National Academy of Sciences.

Flow-enhanced adhesion regulated by a selectin interdomain hinge

Jizhong Lou, Cheng Zhu, Wei Chen, 2006, The Journal of cell biology.

Thiabendazole inhibits ubiquinone reduction activity of mitochondrial respiratory complex II via a water molecule mediated binding feature

Jizhong Lou, Yujia Zhai, F. Sun, 2011, Protein & Cell.

Simulated Thermal Unfolding of the von Willebrand Factor A Domains

Jizhong Lou, Cheng Zhu, Wei Chen, 2010 .

Catch bonds: physical models, structural bases, biological function and rheological relevance.

Jizhong Lou, Cheng Zhu, J. Lou, 2005, Biorheology.

Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase.

Jizhong Lou, Bingquan Gao, Fei Sun, 2017, Nature chemical biology.

Forcing Switch from Short- to Intermediate- and Long-lived States of the αA Domain Generates LFA-1/ICAM-1 Catch Bonds*

Jizhong Lou, Cheng Zhu, Wei Chen, 2010, The Journal of Biological Chemistry.

Flow-induced structural transition in the beta-switch region of glycoprotein Ib.

Klaus Schulten, Jizhong Lou, Cheng Zhu, 2008, Biophysical journal.

Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition.

Jizhong Lou, Cheng Zhu, Baoyu Liu, 2019, Molecular cell.

Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF.

Jizhong Lou, Cheng Zhu, Larry V McIntire, 2008, The Journal of clinical investigation.

Molecular Dynamics Simulated Unfolding of von Willebrand Factor A Domains by Force

Jizhong Lou, Cheng Zhu, Wei Chen, 2009 .

Mechanisms for Flow-Enhanced Cell Adhesion

Jizhong Lou, Cheng Zhu, Rodger P. McEver, 2008, Annals of Biomedical Engineering.

Cationic amphiphilic drugs self-assemble to the core–shell interface of PEGylated phospholipid micelles and stabilize micellar structure

Zhonghua Wu, Jizhong Lou, Jing Wang, 2013, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

Force history dependence of receptor-ligand dissociation.

Jizhong Lou, Cheng Zhu, J. Lou, 2005, Biophysical journal.