Padma-Sheela Jayaraman

发表

Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Debra L. Fulton, Jeffrey M. Gimble, Matthew E. Burow, 2015, Breast Cancer Research.

The Proline Rich Homeodomain Protein PRH/Hhex Forms Stable Oligomers That Are Highly Resistant to Denaturation

P. Jayaraman, K. Gaston, A. Shukla, 2012, PloS one.

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors

P. Noy, P. Jayaraman, K. Gaston, 2008, The Biochemical journal.

The Proline-rich Homeodomain Protein Recruits Members of the Groucho/Transducin-like Enhancer of Split Protein Family to Co-repress Transcription in Hematopoietic Cells*

P. Jayaraman, S. Stifani, T. Swingler, 2004, Journal of Biological Chemistry.

The homeodomain protein PRH influences the differentiation of haematopoietic cells.

P. Jayaraman, G. Goodwin, J. Frampton, 2000, Leukemia research.

A runaway PRH/HHEX-Notch3 positive feedback loop drives cholangiocarcinoma and determines response to CDK4/6 inhibition.

S. Oltean, P. Jayaraman, S. Afford, 2019, Cancer research.

Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth

P. Jayaraman, K. Gaston, A. Shaaban, 2017, Oncogenesis.

CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation

P. Jayaraman, K. Gaston, S. Chaudhri, 2017, Oncogenesis.

Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion

P. Jayaraman, K. Gaston, K. Wadey, 2016, Cell & Bioscience.

PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin

P. Jayaraman, Y. Siddiqui, Daniel Roberts, 2014, Oncogene.

Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes

P. Noy, P. Jayaraman, K. Gaston, 2012, Leukemia research.

Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms to de-repress VEGF-signalling genes and promote cell survival

P. Noy, P. Jayaraman, K. Gaston, 2012, Nucleic acids research.

PRH/Hhex Controls Cell Survival through Coordinate Transcriptional Regulation of Vascular Endothelial Growth Factor Signaling

Kevin Gaston, Padma-Sheela Jayaraman, P. Noy, 2010, Molecular and Cellular Biology.

PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate

P. Jayaraman, A. Soufi, Padma-Sheela Jayaraman, 2008, The Biochemical journal.

University of Birmingham CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding

M. Buckle, K. Gaston, A. Soufi, 2009 .

Activation of Proteinase-Activated Receptor 2 Stimulates Soluble Vascular Endothelial Growth Factor Receptor 1 Release via Epidermal Growth Factor Receptor Transactivation in Endothelial Cells

M. Hollenberg, P. Jayaraman, Samir Sissaoui, 2010, HYPERTENSION.

The Transcription Factor Encyclopedia

Debra L. Fulton, Henriette O'Geen, Elodie Portales-Casamar, 2012, Genome Biology.

The Transcription Factor Encyclopedia The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

Debra L. Fulton, Magdalena I. Swanson, Jonathan S. Lim, 2012 .

Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice

P. Jayaraman, K. Gaston, Jason L. Johnson, 2023, Arteriosclerosis, thrombosis, and vascular biology.

CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding

A. Soufi, A. Sawasdichai, Kevin Gaston, 2009, Nucleic acids research.

The transcriptional repressor protein PRH interacts with the proteasome.

P. Jayaraman, K. Gaston, A. Rivett, 2003, The Biochemical journal.

Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX

P. Jayaraman, K. Gaston, A. Poole, 2020, Oncogenesis.

Targeting protein kinase CK2 in the treatment of cholangiocarcinoma

P. Jayaraman, K. Gaston, Padma-Sheela Jayaraman, 2021, Exploration of targeted anti-tumor therapy.

University of Birmingham Blood platelets stimulate cancer cell extravasation through TGF-mediated down-regulation of PRH/HHEX

P. Jayaraman, A. Poole, Y. Siddiqui, 2020 .

Wireless electrical–molecular quantum signalling for cancer cell apoptosis

F. Rawson, D. Amabilino, R. Rahman, 2023, Nature nanotechnology.

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients

B. Göttgens, J. Landry, S. Kinston, 2010, Oncogene.

Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression*

P. Jayaraman, V. Tkachuk, D. Cines, 2016, The Journal of Biological Chemistry.

Additional file 5

Debra L. Fulton, Albert Kriegner, Martin Lauss, 2009 .

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

J. Brickman, D. Stainier, P. Jayaraman, 2018, Nature Communications.

Additional file 6

Fabio Stella, Alessandro Pandini, Debra L. Fulton, 2009 .

Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism

P. Jayaraman, K. Gaston, S. George, 2017, Vascular pharmacology.

Sequence of CX-4945 and Cisplatin Administration Determines the Effectiveness of Drug Combination and Cellular Response in Cholangiocarcinoma Cells In Vitro

P. Jayaraman, K. Gaston, J. Satayavivad, 2021, AntiCancer Research.