Keith J. Chappell

发表

An Optimized High-Throughput Immuno-Plaque Assay for SARS-CoV-2

P. Young, A. Khromykh, D. Watterson, 2021, Frontiers in Microbiology.

Pathogenesis, Humoral Immune Responses, and Transmission between Cohoused Animals in a Ferret Model of Human Respiratory Syncytial Virus Infection

Louise A. Carolan, L. Carolan, I. Barr, 2017, Journal of Virology.

Structure and antigenicity of divergent Henipavirus fusion glycoproteins

Cassandra L. Pegg, B. Schulz, M. Landsberg, 2023, Nature communications.

Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates

P. Young, D. Bailey, S. Graham, 2021, Viruses.

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

Cassandra L. Pegg, B. Schulz, A. Khromykh, 2023, bioRxiv.

Product release is rate-limiting for catalytic processing by the Dengue virus protease

D. Fairlie, P. Young, G. Schenk, 2016, Scientific Reports.

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG

V. Volchkova, A. Suhrbier, P. Young, 2017, Scientific Reports.

A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants

T. Mielke, C. Spahn, T. Munro, 2023, iScience.

Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial

D. Purcell, K. Subbarao, Thi H. O. Nguyen, 2021, The Lancet Infectious Diseases.

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

P. Reading, D. Watterson, P. Dubois, 2022, Frontiers in Immunology.

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

T. Woodruff, T. Munro, E. Wolvetang, 2022, Molecular Psychiatry.

Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children

P. Sly, P. Holt, P. Young, 2017, Respirology.

Retroviral integrations contribute to elevated host cancer rates during germline invasion

A. Roca, N. Mongan, J. Henning, 2021, Nature Communications.

Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages.

D. Sester, K. Stacey, K. Chappell, 2016, Developmental and comparative immunology.

The Next Generation of Influenza Vaccines: Towards a Universal Solution

P. Young, D. Watterson, K. Chappell, 2021, Vaccines.

Chronic SARS-CoV-2, a Cause of Post-acute COVID-19 Sequelae (Long-COVID)?

K. Chappell, J. S. O’Donnell, Jake S. O’Donnell, 2021, Frontiers in Microbiology.

Pediatric Pulmonology

R. Ware, P. Sly, P. Young, 2020 .

A platform technology for generating subunit vaccines against diverse viral pathogens

P. Woo, K. Kok, A. Marzi, 2022, Frontiers in Immunology.

Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion

G. Taylor, P. Young, D. Bailey, 2020, The Journal of general virology.

Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

C. Palomo, J. Melero, D. Luque, 2012, Proceedings of the National Academy of Sciences.

Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

Benjamin S. Hughes, K. Subbarao, T. Munro, 2021, Clinical & translational immunology.

A broadly protective antibody that targets the flavivirus NS1 protein

G. Gao, Hao Song, Y. Chai, 2021, Science.

The piRNA Response to Retroviral Invasion of the Koala Genome

Z. Weng, J. Luban, W. Theurkauf, 2019, Cell.

Koala retrovirus load and non-A subtypes are associated with secondary disease among wild northern koalas

P. Young, Michaela D. J. Blyton, K. Chappell, 2022, PLoS pathogens.

Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions

B. Moore, P. Young, Michaela D. J. Blyton, 2021, bioRxiv.

Proteoform-Specific Insights into Cellular Proteome Regulation

P. Collins, J. Gorman, K. Dave, 2016, Molecular & Cellular Proteomics.

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation.

Martin J. Stoermer, Gautier Robin, Jennifer L. Martin, 2009, Journal of molecular biology.

West Nile Virus NS2B/NS3 protease as an antiviral target.

Martin J. Stoermer, D. Fairlie, P. Young, 2008, Current medicinal chemistry.

Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3.

Martin J. Stoermer, D. Fairlie, P. Young, 2007, Protein expression and purification.

Enzymatic Characterization and Homology Model of a Catalytically Active Recombinant West Nile Virus NS3 Protease*

Martin J. Stoermer, D. Fairlie, P. Young, 2004, Journal of Biological Chemistry.

Koala retrovirus genetic diversity and transmission dynamics within captive koala populations

P. Young, S. Johnston, Michaela D. J. Blyton, 2021, Proceedings of the National Academy of Sciences.

Distinct systems serology features in children, elderly and COVID patients

S. Kent, Thi H. O. Nguyen, K. Kedzierska, 2020, medRxiv.

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

P. Young, M. Cooper, M. Butler, 2016, Scientific Reports.