S. O. Dahms

发表

Localization and orientation of heavy-atom cluster compounds in protein crystals using molecular replacement

N. Sträter, C. Roth, C. Streb, 2013, Acta crystallographica. Section D, Biological crystallography.

Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors

H. Kolmar, O. Avrutina, M. Than, 2015, Chembiochem : a European journal of chemical biology.

The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities

Pitter F. Huesgen, P. Briza, H. Brandstetter, 2021, ACS catalysis.

Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition

Pitter F. Huesgen, H. Brandstetter, C. Cabrele, 2020, The Journal of Biological Chemistry.

ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease

Pitter F. Huesgen, H. Brandstetter, Fatih Demir, 2020, Analytical chemistry.

Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.

H. Klenk, W. Garten, Kornelia Hardes, 2015, Antiviral research.

Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism

A. Pautsch, H. Brandstetter, G. Schnapp, 2022, ACS chemical biology.

OFF-State-Specific Inhibition of the Proprotein Convertase Furin

G. Klebe, H. Brandstetter, T. Steinmetzer, 2021, ACS chemical biology.

The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin

G. Klebe, R. Bartenschlager, H. Brandstetter, 2021, ACS medicinal chemistry letters.

Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.

M. Than, G. Jiao, S. O. Dahms, 2017, ACS chemical biology.

X-ray Structures of Human Furin in Complex with Competitive Inhibitors

H. Brandstetter, Kornelia Hardes, T. Steinmetzer, 2014, ACS chemical biology.

Legumain Functions as a Transient TrkB Sheddase

C. Huber, H. Brandstetter, S. Dahms, 2023, International journal of molecular sciences.

Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes

G. Multhaup, M. Than, S. Dahms, 2015, Acta crystallographica. Section D, Biological crystallography.

Analysis of the Overall Structure of the Multi-Domain Amyloid Precursor Protein (APP)

P. Hortschansky, M. Than, S. Dahms, 2013, PloS one.

Metal binding dictates conformation and function of the amyloid precursor protein (APP) E2 domain.

G. Multhaup, M. Than, S. Dahms, 2012, Journal of molecular biology.

Optimization of Substrate‐Analogue Furin Inhibitors

I. Lindberg, R. Bartenschlager, Kornelia Hardes, 2017, ChemMedChem.

Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein

M. Than, B. Schlott, S. Dahms, 2010, Proceedings of the National Academy of Sciences.

Novel Furin Inhibitors with Potent Anti‐infectious Activity

I. Lindberg, W. Garten, K. Sandvig, 2015, ChemMedChem.