Paolo D. A. Vignali

Metabolic support of tumor-infiltrating regulatory T cells by lactic acid

J. Rothstein, Greg M. Delgoffe, B. Morrison, 2020, Nature.

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Greg M. Delgoffe, Yiyang Wang, A. Poholek, 2021, Nature immunology.

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Greg M. Delgoffe, S. Robson, A. Poholek, 2022, Nature Immunology.

Tumor hypoxia drives suppressor function in exhausted T cells limiting antitumor immunity

Ashley V. Menk, Greg M. Delgoffe, Ashley V Menk, 2021, Journal for ImmunoTherapy of Cancer.

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Greg M. Delgoffe, Yiyang Wang, A. Poholek, 2021, Nature Immunology.

512 Terminally exhausted CD8+ T cells potentiate the tolerogenic tumor microenvironment as functional suppressors

Greg M. Delgoffe, Ashley V Menk, Nicole E. Scharping, 2020, Journal for ImmunoTherapy of Cancer.

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

Greg M. Delgoffe, A. Poholek, Nicole E. Scharping, 2022, Science Immunology.

Altered costimulatory signals and hypoxia support chromatin landscapes limiting the functional potential of exhausted T cells in cancer

Greg M. Delgoffe, A. Poholek, Nicole E. Scharping, 2021, bioRxiv.