James L. Trevaskis

发表

A. Butler, C. Morrison, J. Trevaskis, 2006 .

Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source

D. Tabor, J. Jelsing, N. Vrang, 2019, World journal of gastroenterology.

Pancreatic β-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes

C. Rondinone, C. Rhodes, R. Grønlund, 2018, Diabetes.

Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight

K. White, M. Das, L. A. Burns-Naas, 2020, PloS one.

Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.

M. Larsen, O. McGuinness, L. Jermutus, 2020, Nature metabolism.

Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

Christian Weyer, B. Roland, C. Anderson, 2008, Proceedings of the National Academy of Sciences.

Tanis: a link between type 2 diabetes and inflammation?

Ken Walder, Lakshmi Kantham, Kelly Windmill, 2002, Diabetes.

Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight

B. Roland, Soumitra S Ghosh, S. Adams, 2010, International Journal of Obesity.

Differential Effects of a Glucagon-Like Peptide 1 Receptor Agonist in Non-Alcoholic Fatty Liver Disease and in Response to Hepatectomy

Á. Valverde, C. Rondinone, C. Barbas, 2018, Scientific Reports.

The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

H. Berthoud, H. Münzberg, C. Morrison, 2019, Nutrients.

Synergistic metabolic benefits of an exenatide analogue and cholecystokinin in diet‐induced obese and leptin‐deficient rodents

D. Parkes, L. D’Souza, J. Trevaskis, 2015, Diabetes, obesity & metabolism.

1 The PYY / Y 2 R-deficient mouse responds normally to 2 high-fat diet and gastric bypass surgery 3

H. Münzberg, C. Morrison, Sangho Yu, 2019 .

Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding

D. Olson, R. Seeley, M. Myers, 2020, Cell metabolism.

Identification of hypothalamic genes implicated in the development of obesity in Psammomys obesus using differential display PCR.

K. Walder, G. Collier, J. Trevaskis, 2003, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Essential Role for Hypothalamic Calcitonin Receptor[FIGURE DASH]Expressing Neurons in the Control of Food Intake by Leptin

D. Olson, M. Myers, J. Flak, 2018, Endocrinology.

Improved Glucose Control and Reduced Body Weight in Rodents with Dual Mechanism of Action Peptide Hybrids

Soumitra S Ghosh, B. Gedulin, C. Jodka, 2013, PloS one.

Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice.

B. Neuschwander‐Tetri, D. Parkes, E. Brunt, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction

J. Lapointe, C. Rhodes, Michelle L. Boland, 2018, World journal of gastroenterology.

Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries

J. Hecksher-Sørensen, O. McGuinness, Jotham Austin, 2021, Molecular metabolism.

A GLP-1:CCK fusion peptide harnesses the synergistic effects on metabolism of CCK-1 and GLP-1 receptor agonism in mice

M. Coghlan, C. Blouet, Victor G. Howard, 2018, Appetite.

Robust anti‐obesity and metabolic effects of a dual GLP‐1/glucagon receptor peptide agonist in rodents and non‐human primates

M. Bednarek, L. Jermutus, C. Rondinone, 2016, Diabetes, obesity & metabolism.

Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment

J. Osbourn, A. Celeste, C. Rondinone, 2018, Scientific Reports.

Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms.

C. Weyer, A. Baron, B. Walsh, 2008, Endocrinology.

Mechanisms of amylin/leptin synergy in rodent models.

D. Parkes, B. Levin, J. Trevaskis, 2010, Endocrinology.

Insights into amylin–leptin synergy

D. Parkes, J. Trevaskis, J. Roth, 2010, Trends in Endocrinology & Metabolism.

Interaction of Leptin and Amylin in the Long‐term Maintenance of Weight Loss in Diet‐induced Obese Rats

C. Weyer, D. Parkes, J. Koda, 2010, Obesity.

A Life without Hunger: The Ups (and Downs) to Modulating Melanocortin-3 Receptor Signaling

D. Marks, A. Butler, S. Farr, 2017, Front. Neurosci..

Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice

H. Berthoud, H. Münzberg, C. Rhodes, 2019, Molecular metabolism.

Rapid Development of Non-Alcoholic Steatohepatitis in Psammomys obesus (Israeli Sand Rat)

R. Standish, A. El-Osta, M. Ziemann, 2014, PloS one.

Transgenic Models Targeting the Central Nervous System

A. Butler, G. Sutton, J. Trevaskis, 2007 .

Gut check on diabesity: leveraging gut mechanisms for the treatment of type 2 diabetes and obesity

M. Coghlan, D. Baker, J. Trevaskis, 2017, Current opinion in pharmacology.

Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in C57BL/6J mice.

J. Galgani, A. Butler, J. Trevaskis, 2008, Endocrinology.

Effects of prior or concurrent food restriction on amylin-induced changes in body weight and body composition in high-fat-fed female rats.

C. Anderson, J. Trevaskis, J. Roth, 2007, American journal of physiology. Endocrinology and metabolism.

Of Mice and Men: Translational Research on Amylin Agonism

D. Parkes, C. Mack, J. Trevaskis, 2011 .

Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats.

D. Parkes, J. Reynolds, C. Mack, 2010, Endocrinology.

Diet-Induced Obese Rats Enhanced Amylin-Mediated Body Weight Loss in Estradiol-Deficient

J. Reynolds, J. Trevaskis, P. Griffin, 2010 .

“Weighing in” on synergy: Preclinical research on neurohormonal anti-obesity combinations

D. Parkes, J. Trevaskis, J. Roth, 2010, Brain Research.

Multi-hormonal weight loss combinations in diet-induced obese rats: Therapeutic potential of cholecystokinin?

D. Parkes, J. Trevaskis, J. Roth, 2010, Physiology & Behavior.

Targeting lipid biosynthesis pathways for hepatitis B virus cure

William A. Lee, Meghan M. Holdorf, S. Fletcher, 2022, PloS one.

Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis

J. Jelsing, N. Vrang, F. Knop, 2020, BMC Gastroenterology.

Calpain 3 gene expression in skeletal muscle is associated with body fat content and measures of insulin resistance

P Zimmet, P. Zimmet, A. Kriketos, 2002, International Journal of Obesity.

Bifunctional PEGylated exenatide-amylinomimetic hybrids to treat metabolic disorders: an example of long-acting dual hormonal therapeutics.

Soumitra S Ghosh, C. Jodka, D. Parkes, 2013, Journal of medicinal chemistry.

Interactions of amylinergic and melanocortinergic systems in the control of food intake and body weight in rodents

C. Jodka, D. Parkes, J. Hoyt, 2012, Diabetes, obesity & metabolism.