Khaled El‐Adl

发表

Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors.

M. Elsohly, M. M. Khalifa, M. Radwan, 2020, Bioorganic & medicinal chemistry.

Design, synthesis, molecular docking and anticancer evaluations of 5-benzylidenethiazolidine-2,4-dione derivatives targeting VEGFR-2 enzyme.

I. Eissa, Khaled El-Adl, Abdel-Ghany A. El-Helby, 2020, Bioorganic chemistry.

Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation.

M. Elsohly, M. M. Khalifa, M. Radwan, 2020, Bioorganic chemistry.

Anticancer evaluations of iodoquinazoline substituted with allyl and/or benzyl as dual inhibitors of EGFRWT and EGFRT790M: design, synthesis, ADMET and molecular docking

S. Mohamady, A. El-Morsy, Omar M. Alatawi, 2024, RSC advances.

Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation.

M. Elsohly, M. Radwan, I. Eissa, 2021, Bioorganic chemistry.

Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents.

I. Eissa, M. El-Zahabi, Khaled El-Adl, 2020, Bioorganic chemistry.

In silico ADMET, docking, anti-proliferative and antimicrobial evaluations of ethanolic extract of Euphorbia dendroides L.

F. Ahmed, Khaled El-Adl, Mostafa M. Elhady, 2022, South African Journal of Botany.

Quinazolines and thiazolidine-2,4-dions as SARS-CoV-2 inhibitors: repurposing, in silico molecular docking and dynamics simulation

A. El-Morsy, Sanadelaslam S A El-Hddad, Khaled El‐Adl, 2024, RSC Advances.

In silico molecular docking, dynamics simulation and repurposing of some VEGFR-2 inhibitors based on the SARS-CoV-2-main-protease inhibitor N3

Khaled El-Adl, Sanadelaslam S A El-Hddad, M. Sobhy, 2022, Journal of biomolecular structure & dynamics.

Design, synthesis, docking, ADMET profile, and anticancer evaluations of novel thiazolidine‐2,4‐dione derivatives as VEGFR‐2 inhibitors

Khaled El-Adl, Abdel-Ghany A. El-Helby, Helmy M. Sakr, 2021, Archiv der Pharmazie.

Design, synthesis, molecular docking, anticancer evaluations, and in silico pharmacokinetic studies of novel 5‐[(4‐chloro/2,4‐dichloro)benzylidene]thiazolidine‐2,4‐dione derivatives as VEGFR‐2 inhibitors

Khaled El-Adl, Abdel-Ghany A. El-Helby, Helmy M. Sakr, 2020, Archiv der Pharmazie.

Design, synthesis, docking, and anticancer evaluations of phthalazines as VEGFR‐2 inhibitors

I. Eissa, M. Ibrahim, Khaled El-Adl, 2021, Archiv der Pharmazie.

Pyrazolo[3,4-d]pyrimidine derivatives as EGFRT790M and VEGFR-2 dual TK inhibitors: Design, synthesis, molecular docking, ADMET profile and anticancer evaluations

Khaled El-Adl, T. Sakr, W. Zaghary, 2023, Journal of Molecular Structure.

Benzoxazole/benzothiazole‐derived VEGFR‐2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluations

I. Eissa, Khaled El-Adl, Abdel-Ghany A. El-Helby, 2019, Archiv der Pharmazie.

Design, synthesis, molecular docking, and anticancer activity of benzoxazole derivatives as VEGFR‐2 inhibitors

I. Eissa, Khaled El-Adl, Abdel-Ghany A. El-Helby, 2019, Archiv der Pharmazie.

Design, Synthesis, Molecular Docking, and Anticancer Activity of Phthalazine Derivatives as VEGFR‐2 Inhibitors

Mamdouh M. Ali, Khaled El-Adl, Abdel-Ghany A. El-Helby, 2017, Archiv der Pharmazie.

New quinoxaline-2(1H)-ones as potential VEGFR-2 inhibitors: design, synthesis, molecular docking, ADMET profile and anti-proliferative evaluations

M. Elsohly, M. Radwan, I. Eissa, 2021, New Journal of Chemistry.

Exploration of cytotoxicity of iodoquinazoline derivatives as inhibitors of both VEGFR-2 and EGFRT790M: Molecular docking, ADMET, design, and syntheses.

Sanadelaslam S A El-Hddad, Omar M. Alatawi, Samar F Miski, 2024, Archiv der Pharmazie.

Iodoquinazoline-derived VEGFR-2 and EGFRT790M dual inhibitors: Design, synthesis, molecular docking and anticancer evaluations.

Fathalla Khedr, Omar M. Alatawi, Noura S Hanafy, 2023, Bioorganic chemistry.

New quinazoline sulfonamide derivatives as potential anticancer agents: Identifying a promising hit with dual EGFR/VEGFR-2 inhibitory and radiosensitizing activity.

M. Ghorab, A. M. Soliman, Khaled El-Adl, 2023, Bioorganic chemistry.

Design, synthesis, and docking of novel thiazolidine‐2,4‐dione multitarget scaffold as new approach for cancer treatment

M. Ghoneim, Sahar Ahmed, Khaled El-Adl, 2023, Archiv der Pharmazie.

Exploration of thiazolidine‐2,4‐diones as tyrosine kinase inhibitors: Design, synthesis, ADMET, docking, and antiproliferative evaluations

Riham F. George, Khaled El-Adl, Walaa R Mahmoud, 2022, Archiv der Pharmazie.

Design, synthesis, in silico docking, ADMET and anticancer evaluations of thiazolidine-2,4-diones bearing heterocyclic rings as dual VEGFR-2/EGFRT790M tyrosine kinase inhibitors

Riham F. George, Khaled El-Adl, Walaa R Mahmoud, 2022, RSC advances.

Design, Molecular Docking, Synthesis, Anticancer and Anti-Hyperglycemic Assessments of Thiazolidine-2,4-diones Bearing Sulfonylthiourea Moieties as Potent VEGFR-2 Inhibitors and PPARγ Agonists

M. Abdelgawad, M. Ghoneim, M. M. Khalifa, 2022, Pharmaceuticals.

5‐(4‐Methoxybenzylidene)thiazolidine‐2,4‐dione‐derived VEGFR‐2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluations

Khaled El-Adl, Helmy M. Sakr, Mohamed Alswah, 2020, Archiv der Pharmazie.

Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies.

Farag F. Sherbiny, Rogy R Ezz Eldin, Marwa A Saleh, 2021, Archiv der Pharmazie.

Synthesis, antimicrobial evaluation, DNA gyrase inhibition, and in silico pharmacokinetic studies of novel quinoline derivatives

Hany E. A. Ahmed, Khaled El-Adl, Hamada S. Abulkhair, 2020, Archiv der Pharmazie.

Unravelling the anticancer potency of 1,2,4-triazole-N-arylamide hybrids through inhibition of STAT3: synthesis and in silico mechanistic studies

Farag F. Sherbiny, Khaled El-Adl, Hamada S. Abulkhair, 2020, Molecular Diversity.

The antimicrobial potential and pharmacokinetic profiles of novel quinoline-based scaffolds: synthesis and in silico mechanistic studies as dual DNA gyrase and DHFR inhibitors

Hany E. A. Ahmed, Khaled El-Adl, Hamada S. Abulkhair, 2021, New Journal of Chemistry.

Novel promising benzoxazole/benzothiazole‐derived immunomodulatory agents: Design, synthesis, anticancer evaluation, and in silico ADMET analysis

M. El-Zahabi, Khaled El-Adl, Helmy M. Sakr, 2023, Archiv der Pharmazie.

Immunomodulatory quinazoline-based thalidomide analogs: Design, synthesis, apoptosis and anticancer evaluations

I. Eissa, M. El-Zahabi, Ahmed B. M. Mehany, 2023, Journal of Molecular Structure.

Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors.

Khaled El-Adl, M. El‐Gaby, N. Saleh, 2020, Bioorganic chemistry.

Design, synthesis, anticancer, and docking of some S‐ and/or N‐heterocyclic derivatives as VEGFR‐2 inhibitors

Khaled El-Adl, A. Abdel-Rahman, Asmaa M A Omar, 2021, Archiv der Pharmazie.

Design, synthesis, molecular docking and in silico ADMET profile of pyrano[2,3-d]pyrimidine derivatives as antimicrobial and anticancer agents.

S. Salama, Khaled El-Adl, M. El-Hashash, 2021, Bioorganic chemistry.