Y. Saito

发表

Pancreatic polypeptide is secreted from and controls differentiation through its specific receptors in osteoblastic MC3T3-E1 cells

T. Nagao, Tomoaki Tanaka, I. Tatsuno, 2008, Peptides.

Effects of weight loss in obese subjects with normal fasting plasma glucose or impaired glucose tolerance on insulin release and insulin resistance according to a minimal model analysis.

A. Kanatsuka, K. Yagui, H. Bujo, 2004, Metabolism: clinical and experimental.

Mitogen-activated protein kinase and p70 ribosomal protein S6 kinase are not involved in the insulin-dependent stimulation of cAMP phosphodiesterase kinase in rat adipocytes.

H. Onuma, H. Makino, H. Osawa, 1998, Biochimica et biophysica acta.

Comparison between morning and evening doses of simvastatin in hyperlipidemic subjects. A double-blind comparative study.

N. Nakaya, Y. Hata, Y. Goto, 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice.

Kotaro Suzuki, M. Hatano, T. Tokuhisa, 2006, The Journal of allergy and clinical immunology.

Enhanced Th2 Cell-Mediated Allergic Inflammation in Tyk2-Deficient Mice1

K. Nakayama, H. Nakajima, A. Suto, 2003, The Journal of Immunology.

Primary Cardiovascular Events and Serum Lipid Levels in Elderly Japanese with Hypercholesterolemia Undergoing 6‐Year Simvastatin Treatment: A Subanalysis of the Japan Lipid Intervention Trial

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2004, Journal of the American Geriatrics Society.

Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia.

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Bisphenol A affects glucose transport in mouse 3T3‐F442A adipocytes

K. Sakurai, T. Adachi, C. Mori, 2004, British journal of pharmacology.

Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activation.

Yasuo Suzuki, Y. Saito, Mako Kinoshita, 2002, Biochemical and biophysical research communications.

A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia.

J. Sasaki, N. Yamada, H. Mabuchi, 2002, Atherosclerosis.

Suppression of neointimal thickening by a newly developed HMG‐CoA reductase inhibitor, BAYw6228, and its inhibitory effect on vascular smooth muscle cell growth

M. Igarashi, Y. Saito, S. Mori, 1997, British journal of pharmacology.

Hypolipidemic Effect of NK-104 and Other 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors in Guinea Pigs

M. Kitahara, T. Tamaki, Y. Saito, 2001, Arzneimittelforschung.

Lipid-lowering and Antiatherosclerotic Effect of NK-104, a Potent 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitor, in Watanabe Heritable Hyperlipidemic Rabbits

M. Kitahara, T. Tamaki, T. Aoki, 2000, Arzneimittelforschung.

High-Density Lipoprotein Cholesterol and Cardiovascular Events in Patients with Stable Coronary Artery Disease Treated with Statins: An Observation from the REAL-CAD Study

Y. Ohashi, M. Matsuzaki, T. Hiro, 2021, Journal of atherosclerosis and thrombosis.

Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ubiquinone levels in rat skeletal muscle and heart: relationship to cytotoxicity and inhibitory activity for cholesterol synthesis in human skeletal muscle cells.

T. Kodama, S. Morikawa, T. Maejima, 2006, Journal of atherosclerosis and thrombosis.

Design and baseline characteristics of a cohort study in Japanese patients with hypercholesterolemia: the Japan lipid intervention trial (J-LIT)

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2000 .

Clinical Efficacy of Pitavastatin, a New 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitor, in Patients with Hyperlipidemia

J. Sasaki, N. Yamada, H. Mabuchi, 2002, Arzneimittelforschung.

Effects of Long‐Term Treatment with Probucol on Serum Lipoproteins in Cases of Familial Hypercholesterolemia in the Elderly

M. Shinomiya, K. Shirai, J. Kobayashi, 1990, Journal of the American Geriatrics Society.

Ligation of CD31 (PECAM-1) on Endothelial Cells Increases Adhesive Function of vβ3 Integrin and Enhances β1 Integrin-Mediated Adhesion of Eosinophils to Endothelial Cells

Yoshiya Tanaka, I. Iwamoto, K. Kurasawa, 1999 .

IL-4–Stat6 Signaling Induces Tristetraprolin Expression and Inhibits TNF-α Production in Mast Cells

Kotaro Suzuki, Y. Maezawa, Yasushi Saito, 2003, The Journal of experimental medicine.

Stat6-protease but not Stat5-protease is inhibited by an elastase inhibitor ONO-5046.

Kotaro Suzuki, T. Hiwasa, Yasushi Saito, 2003, Biochemical and biophysical research communications.

Proteolytic Processing of Stat6 Signaling in Mast Cells as a Negative Regulatory Mechanism

S. Akira, K. Takeda, Kotaro Suzuki, 2002, The Journal of experimental medicine.

Inflammation in Tyk 2-Deficient Mice Enhanced Th 2 Cell-Mediated Allergic

K. Nakayama, H. Nakajima, A. Suto, 2002 .

Long-term probucol treatment prevents secondary cardiovascular events: a cohort study of patients with heterozygous familial hypercholesterolemia in Japan.

S. Yamashita, Y. Matsuzawa, T. Kita, 2008, Journal of atherosclerosis and thrombosis.

Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line Cε transcription of IL-4–stimulated B cells

Kotaro Suzuki, Yasushi Saito, H. Nakajima, 2002 .

Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line C(epsilon) transcription of IL-4-stimulated B cells.

Kotaro Suzuki, Yasushi Saito, H. Nakajima, 2002, Blood.

CD4(+)CD25(+) T-cell development is regulated by at least 2 distinct mechanisms.

M. Taniguchi, T. Nakayama, H. Nakajima, 2002, Blood.

Janus kinase 3 (Jak3) is essential for common cytokine receptor γ chain (γc)-dependent signaling: comparative analysis of γc, Jak3, and γc and Jak3 double-deficient mice

Hiroshi Nakajima, Takashi Saito, Yasushi Saito, 2000 .

CD 4 1 CD 25 1 T-cell development is regulated by at least 2 distinct mechanisms

M. Taniguchi, T. Nakayama, H. Nakajima, 2001 .

Degradation Process of Ligand-stimulated Platelet-derived Growth Factor β -Receptor Involves Ubiquitin-Proteasome Proteolytic Pathway *

S. Ōmura, K. Tanaka, Y. Saito, 1995, The Journal of Biological Chemistry.

Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes.

T. Imaizumi, S. Yamagishi, M. Takeuchi, 2007, Diabetes research and clinical practice.

Fibronectin promotes cell proliferation of human pre-B cell line via its interactions with VLA-4 and VLA-5

M. Kitagawa, C. Morimoto, C. Nakaseko, 2008, Hematology.

Atherosclerosis induced by chronic inhibition of the synthesis of nitric oxide in moderately hypercholesterolaemic rabbits is suppressed by pitavastatin

M. Kitahara, T. Kanaki, I. Ishii, 2010, British journal of pharmacology.

Effect of HDL, from Japanese white rabbit administered a new cholesteryl ester transfer protein inhibitor JTT-705, on cholesteryl ester accumulation induced by acetylated low density lipoprotein in J774 macrophage.

H. Okamoto, J. Kobayashi, H. Bujo, 2002, Atherosclerosis.

Mammalian Polycomb complexes are required for Peyer's patch development by regulating lymphoid cell proliferation.

H. Koseki, M. Endoh, K. Isono, 2006, Gene.

Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs.

S. Nishikawa, Hiroshi Sato, M. Taniguchi, 2003, Developmental biology.

Characteristic Features of Long‐Living Patients with Familial Hypercholesterolemia in Japan

M. Shinomiya, K. Shirai, Y. Saito, 1993, Journal of the American Geriatrics Society.

Moderate oxidation of hypertriglyceridemic low-density lipoprotein causes apolipoprotein B epitope change and enhances its uptake by macrophages.

H. Inadera, K. Shirai, Y. Saito, 1992, Biochimica et biophysica acta.

N. Morisaki, S. Mori, S. Yoshida, 1988, Mechanisms of Ageing and Development.

Incorporation of [1‐14C]Palmitic Acid into Neutral Lipids and Phospholipids of Rat Cerebral Cortex In Vitro

N. Morisaki, A. Kumagai, N. Matsuoka, 1982, Journal of neurochemistry.

A Clinical Feature of Diabetes Insipidus Hyperlipid emia in Patients with Central

J. Kobayashi, N. Morisaki, H. Bujo, 2006 .

Effect of High Density Lipoproteins Modified with Dilinoleoylphosphatidylcholine Vesicles on [3H]Cholesterol Release from Macrophages

K. Shirai, Yasushi Saito, S. Yoshida, 1987 .

Identification and characterization of high glucose and glucosamine responsive element in the rat osteopontin promoter.

H. Kawamura, K. Yokote, M. Takemoto, 2003, Journal of diabetes and its complications.

Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells.

N. Morisaki, Y. Saito, S. Yoshida, 1992, The Journal of biological chemistry.

Eicosapentaenoic acid (EPA) reduces cardiovascular events: relationship with the EPA/arachidonic acid ratio.

Yasushi Saito, H. Ohnishi, Y. Saito, 2013, Journal of atherosclerosis and thrombosis.

Increased Circulating Malondialdehyde-Modified LDL Levels in Patients With Coronary Artery Diseases and Their Association With Peak Sizes of LDL Particles

Yasushi Saito, H. Bujo, T. Kanno, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Clostridium butyricum TO-A Culture Supernatant Downregulates TLR4 in Human Colonic Epithelial Cells

T. Katsuno, Yasuo Suzuki, T. Nakagawa, 2007, Digestive Diseases and Sciences.

A potent activator of PPARα and γ reduces the vascular cell recruitment and inhibits the intimal thickning in hypercholesterolemic rabbits

M. Shibasaki, H. Bujo, Kazuo Takahashi, 2005 .

NK-104: a novel synthetic HMG-CoA reductase inhibitor

H. Mabuchi, K. Kajinami, Y. Saito, 2000, Expert opinion on investigational drugs.

An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice

K. Yokote, M. Takemoto, Ryoichi Ishibashi, 2012, Experimental diabetes research.

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2007, The Lancet.

Restricted Oligo-Clonal Usage of Monoclonal Immunoglobulin λ Light Chain Germline in POEMS Syndrome.

C. Nakaseko, S. Kuwabara, S. Misawa, 2007 .

Association of cytosine-adenine repeat polymorphism of the estrogen receptor-beta gene with menopausal symptoms.

Yasushi Saito, I. Tatsuno, K. Ueno, 2005, Gender medicine.

Pitavastatin: an overview.

Y. Saito, Y. Saito, 2011, Atherosclerosis. Supplements.

Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.

K. Kajinami, N. Takekoshi, Yasushi Saito, 2006, Cardiovascular drug reviews.

Treatment Options for Hypercholesterolemia and Combined Dyslipidemia: Focus on Pitavastatin

Y. Saito, Y. Saito, 2011 .

Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese adults.

S. Yamashita, J. Sasaki, N. Yamada, 2002, Journal of atherosclerosis and thrombosis.

Prevalence of metabolic syndrome in the general Japanese population in 2000.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2006, Journal of atherosclerosis and thrombosis.

Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers.

T. Katsuno, Yasuo Suzuki, Aihiro Hoshimoto, 2004, Experimental cell research.

Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2009, Circulation journal : official journal of the Japanese Circulation Society.

Tumor Necrosis Factor-α Mediates Antiapoptotic Signals Partially via p38 MAP Kinase Activation in Human Eosinophils

A. Nakao, Yasushi Saito, I. Iwamoto, 1999, International Archives of Allergy and Immunology.

Involvement of JAK2, but not PI 3‐kinase/Akt and MAP kinase pathways, in anti‐apoptotic signals of GM‐CSF in human eosinophils

A. Nakao, I. Iwamoto, M. Hiraguri, 1999, Journal of leukocyte biology.

Effect of fenofibrate on uric acid metabolism in Japanese hyperlipidemic patients.

I. Tatsuno, Tomohiko Yoshida, M. Fuse, 2004, Journal of atherosclerosis and thrombosis.

The effects of partial use of formula diet on weight reduction and metabolic variables in obese type 2 diabetic patients--multicenter trial.

N. Sakane, N. Yamada, S. Ishibashi, 2013, Obesity research & clinical practice.

Vasopressin responders have a high prevalence of hypertension and insulin resistance in spite of a lower secretion of cortisol in subclinical Cushing's syndrome.

Tomoaki Tanaka, I. Tatsuno, Yasushi Saito, 2008, Molecular medicine reports.

A possible association between aldosterone response to vasopressin and circadian change of aldosterone in the patients with aldosterone-producing adenoma

Tomoaki Tanaka, I. Tatsuno, Tomohiko Yoshida, 2008, Peptides.

Activation‐induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4+ T cells

K. Murphy, Takashi Saito, T. Murphy, 2010, Journal of leukocyte biology.

T-cell recruitment into the tissue Both Stat5a and Stat5b are required for antigen-induced eosinophil and

W. Leonard, Kotaro Suzuki, K. Takatsu, 2013 .

Stat 5 a and Stat 5 b are required for antigen-induced eosinophil and T-cell recruitment into the tissue

W. Leonard, Kotaro Suzuki, K. Takatsu, 2000 .

Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia

T. Nakajima, M. Emi, Y. Ezura, 2005, Journal of Human Genetics.

New indices of ischemic heart disease and aging: studies on the serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and soluble vascular cell adhesion molecule-1 (VCAM-1) in patients with hypercholesterolemia and ischemic heart disease.

S. Watanabe, M. Masuda, N. Morisaki, 1997, Atherosclerosis.

Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals

Y. Saito, Y. Saito, 2009, Vascular health and risk management.

Randomized dose-response study of rosuvastatin in Japanese patients with hypercholesterolemia.

Y. Goto, A. Dane, A. Raza, 2003, Journal of atherosclerosis and thrombosis.

Optimal target of LDL cholesterol level for statin treatment: challenges to monotonic relationship with cardiovascular events

M. Matsuzaki, H. Daida, Y. Ozaki, 2022, BMC Medicine.

Integrated Analysis of Two Probucol Trials for the Secondary Prevention of Atherosclerotic Cardiovascular Events: PROSPECTIVE and IMPACT

S. Yamashita, Y. Matsuzawa, T. Kita, 2021, Journal of atherosclerosis and thrombosis.

The Role of Smad3-Dependent TGF-β Signal in Vascular Response to Injury

K. Yokote, Kazuki Kobayashi, Y. Saito, 2006 .

Caprylic acid and medium‐chain triglycerides inhibit IL‐8 gene transcription in Caco‐2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A

T. Katsuno, Yasuo Suzuki, H. Nakajima, 2002, British journal of pharmacology.

Mast cells produce interleukin-25 upon FcεRI-mediated activation

Kotaro Suzuki, H. Nakajima, K. Ikeda, 2003 .

Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activation.

Kotaro Suzuki, H. Nakajima, K. Ikeda, 2003, Blood.

Effects of gamma-oryzanol on lipid metabolism in rats fed high-cholesterol diet.

M. Shinomiya, N. Morisaki, Y. Saito, 1983, The Tohoku journal of experimental medicine.

IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice.

M. Hatano, P. Puccetti, T. Tokuhisa, 2008, American journal of respiratory and critical care medicine.

Critical Roles of Muscle-Secreted Angiogenic Factors in Therapeutic Neovascularization

I. Komuro, F. Nomura, T. Minamino, 2006, Circulation research.

Rationale and Design of Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy with Pitavastatin in Coronary Artery Disease (REAL-CAD) Trial.

Y. Ohashi, M. Matsuzaki, T. Hiro, 2018, International heart journal.

Fasciitis and myositis: an analysis of muscle-related complications caused by chronic GVHD after allo-SCT

C. Nakaseko, H. Sakamaki, S. Okamoto, 2009, Bone Marrow Transplantation.

A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro

S. Takasawa, H. Okamoto, H. Makino, 1998, Diabetologia.

Incidence of symptomatic vertebral fracture with high-dose glucocorticoid treatment in the Chiba-Shimoshizu Rheumatic Cohort between 1986 and 2006.

Tomoaki Tanaka, I. Tatsuno, T. Sugiyama, 2009, Endocrine journal.

Age dependence of early symptomatic vertebral fracture with high-dose glucocorticoid treatment for collagen vascular diseases.

Tomoaki Tanaka, I. Tatsuno, T. Sugiyama, 2009, The Journal of clinical endocrinology and metabolism.

Elements of Neural Adhesion Molecules and a Yeast Vacuolar Protein Sorting Receptor Are Present in a Novel Mammalian Low Density Lipoprotein Receptor Family Member*

W. Schneider, T. Kanaki, N. Morisaki, 1996, The Journal of Biological Chemistry.

Enhanced expression of osteopontin in human diabetic artery and analysis of its functional role in accelerated atherogenesis.

T. Shigematsu, K. Yokote, M. Takemoto, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Hyperglycemia-induced alteration of vascular smooth muscle phenotype.

K. Yokote, M. Takemoto, S. Mori, 2002, Journal of diabetes and its complications.

Distinct Roles for CXCR6+ and CXCR6− CD4+ T Cells in the Pathogenesis of Chronic Colitis

O. Yokosuka, K. Hase, Y. Obata, 2013, PloS one.

Abdominal wall fat index, estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen.

R. Suzuki, S. Watanabe, Y. Hirai, 1993, The American journal of medicine.

Serum lipid survey and its recent trend in the general Japanese population in 2000.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2005, Journal of atherosclerosis and thrombosis.

Enhanced Expression of Osteopontin by High Glucose: Involvement of Osteopontin in Diabetic Macroangiopathy a

K. Yokote, M. Takemoto, W. Butler, 2000, Annals of the New York Academy of Sciences.

Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study.

Y. Yamasaki, Y. Ohashi, H. Sone, 2005, Diabetes care.

The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions: additional analysis from the Japan Diabetes Complications Study.

Y. Yamasaki, Y. Ohashi, H. Sone, 2006, Diabetes care.

Platelet-derived Growth Factor Activates p38 Mitogen-activated Protein Kinase through a Ras-dependent Pathway That Is Important for Actin Reorganization and Cell Migration*

H. Ueno, Taro Matsumoto, S. Mori, 1999, The Journal of Biological Chemistry.

Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.

C. Croce, H. Ishii, K. Huebner, 2003, Molecular cancer research : MCR.

Global analysis of RNA expression profile in human vascular cells treated with statins.

T. Kodama, S. Morikawa, T. Hamakubo, 2004, Journal of atherosclerosis and thrombosis.

Lipoprotein(a) Is a Risk Factor for Diabetic Retinopathy in the Elderly

K. Yokote, N. Morisaki, J. Tashiro, 1994, Journal of the American Geriatrics Society.

Prognosis of hypercholesterolemic patients taking pravastatin for five years: the Chiba Lipid Intervention Program (CLIP) Study.

M. Shinomiya, K. Shirai, Yasushi Saito, 2002, Journal of atherosclerosis and thrombosis.

The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells.

T. Kodama, S. Morikawa, T. Kanke, 2002, Journal of atherosclerosis and thrombosis.

Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000.

Y. Ouchi, Y. Matsuzawa, T. Kita, 2005, Journal of atherosclerosis and thrombosis.

The role of the hypoxia-inducible factor 1 binding site in the induction of aquaporin-1 mRNA expression by hypoxia.

K. Sakurai, K. Yokote, K. Yagui, 2011, DNA and cell biology.

Clinical importance of adherence to treatment with eicosapentaenoic acid by patients with hypercholesterolemia.

Y. Matsuzawa, M. Matsuzaki, H. Origasa, 2010, Circulation journal : official journal of the Japanese Circulation Society.

Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia and coronary heart disease: secondary prevention cohort study of the Japan Lipid Intervention Trial (J-LIT).

Y. Matsuzawa, K. Shimamoto, M. Matsuzaki, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-gamma production and the induction of Th1 cell differentiation.

N. Watanabe, H. Nakajima, A. Suto, 2007, Blood.

Technical Advance A New Method for Large Scale Isolation of Kidney Glomeruli from Mice

C. Betsholtz, H. Gerhardt, B. Johansson, 2002 .

Successful control of Epstein–Barr virus (EBV)‐infected cells by allogeneic nonmyeloablative stem cell transplantation in a patient with the lethal form of chronic active EBV infection

C. Nakaseko, S. Hara, M. Nishimura, 2004, American journal of hematology.

Effect of rosuvastatin 5-20mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia.

T. Yanase, J. Sasaki, N. Yamada, 2007, Atherosclerosis.

T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways.

Yasushi Saito, N. Watanabe, H. Nakajima, 2007, The Journal of allergy and clinical immunology.

Preventive effects of eicosapentaenoic acid on coronary artery disease in patients with peripheral artery disease.

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2010, Circulation journal : official journal of the Japanese Circulation Society.

Clinical usefulness of the thickness of preperitoneal and subcutaneous fat layer in the abdomen estimated by ultrasonography for diagnosing abdominal obesity in each type of impaired glucose tolerance in man.

Hiroko Ito, J. Saito, T. Nishikawa, 2005, Endocrine journal.

Eicosapentaenoic Acid and Docosahexaenoic Acid Inhibit DNA Synthesis through Inhibiting cdk2 Kinase in Vascular Smooth Muscle Cells

M. Kitagawa, T. Terano, Y. Tamura, 1997, Annals of the New York Academy of Sciences.

Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3.

K. Yokote, T. Kanaki, N. Morisaki, 2002, Biochemical and biophysical research communications.

Enhanced Expression of the LDL Receptor Family Member LR11 Increases Migration of Smooth Muscle Cells In Vitro

W. Schneider, T. Kanaki, H. Yamazaki, 2002, Circulation.

In Vivo Effect of TGF-β1

N. Morisaki, K. Tamura, M. Ueda, 1995 .

Targeted Disruption of TGF-&bgr;–Smad3 Signaling Leads to Enhanced Neointimal Hyperplasia With Diminished Matrix Deposition in Response to Vascular Injury

T. Tokuhisa, H. Kawamura, K. Yokote, 2005 .

Successful treatment of intravascular malignant lymphomatosis with high-dose chemotherapy and autologous peripheral blood stem cell transplantation

T. Kobayashi, M. Nishimura, A. Yokota, 2001, Bone Marrow Transplantation.

Mechanism of angiogenic effects of saponin from Ginseng Radix rubra in human umbilical vein endothelial cells

N. Morisaki, N. Koyama, T. Kanzaki, 1995, British journal of pharmacology.

Migratory and proliferative effect of platelet‐derived growth factor in rabbit retinal endothelial cells: Evidence of an autocrine pathway of platelet‐derived growth factor

N. Morisaki, S. Yoshida, N. Koyama, 1994, Journal of cellular physiology.

Secretion of a potent new migration factor for smooth muscle cells (SMC) by cultured SMC.

N. Morisaki, Y. Saito, S. Yoshida, 1991, Atherosclerosis.

Bifunctional effects of transforming growth factor-beta on migration of cultured rat aortic smooth muscle cells.

N. Morisaki, Y. Saito, S. Yoshida, 1990, Biochemical and biophysical research communications.

Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).

Y. Matsuzawa, K. Shimada, M. Matsuzaki, 2008, Atherosclerosis.

Effect of glycyrrhizin on lysis of hepatocyte membranes induced by anti‐liver cell membrane antibody

K. Shirai, S. Yoshida, Y. Saito, 1992, Journal of gastroenterology and hepatology.

Involvement of TNF Receptor-Associated Factor 6 in IL-25 Receptor Signaling1

Kotaro Suzuki, J. Inoue, Y. Maezawa, 2006, The Journal of Immunology.

Adipocytes as a vehicle for ex vivo gene therapy: Novel replacement therapy for diabetes and other metabolic diseases

H. Bujo, Masayuki Kuroda, Y. Saito, 2011, Journal of diabetes investigation.

Disturbed apolipoprotein A-I-containing lipoproteins in fish-eye disease are improved by the lecithin:cholesterol acyltransferase produced by gene-transduced adipocytes in vitro.

Y. Aoyagi, H. Bujo, I. Ishii, 2011, Molecular genetics and metabolism.

Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study).

H. Onuma, H. Makino, H. Osawa, 2002, Diabetes care.

Long-term safety and efficacy of TAK-085 in Japanese subjects with hypertriglyceridemia undergoing lifestyle modification: the omega-3 fatty acids randomized long-term (ORL) study.

I. Tatsuno, K. Kudou, Y. Saito, 2013, Journal of clinical lipidology.

Analysis of genes dominantly expressed in rat cerebral endothelial cells using suppression subtractive hybridization.

N. Misawa, I. Tatsuno, Takahisa Shibata, 2005, Journal of atherosclerosis and thrombosis.

LR11, an LDL Receptor Gene Family Member, Is a Novel Regulator of Smooth Muscle Cell Migration

W. Schneider, T. Kanaki, H. Yamazaki, 2004, Circulation research.

Modulation of smooth muscle cell migration by members of the low-density lipoprotein receptor family.

H. Bujo, Y. Saito, Y. Saito, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy.

A. Roberts, H. Kawamura, K. Yokote, 2003, Biochemical and biophysical research communications.

Development and characterization of IL-21–producing CD4+ T cells

T. Nakayama, N. Watanabe, H. Nakajima, 2008, The Journal of experimental medicine.

Indispensable Role of Stat5a in Stat6-Independent Th2 Cell Differentiation and Allergic Airway Inflammation1

Kotaro Suzuki, H. Nakajima, H. Takatori, 2005, The Journal of Immunology.

Role of common cytokine receptor γ chain (γc)– and Jak3-dependent signaling in the proliferation and survival of murine mast cells

Kotaro Suzuki, Takashi Saito, N. Watanabe, 2000 .

and Allergic Airway Inflammation Stat6-Independent Th2 Cell Differentiation Indispensable Role of Stat5a in

H. Nakajima, A. Suto, T. Tamachi, 2013 .

Fc receptor-independent development of autoimmune glomerulonephritis in lupus-prone MRL/lpr mice.

Takashi Saito, N. Watanabe, I. Iwamoto, 2003, Arthritis and rheumatism.

Characteristics of T-cell receptor Vα24JαQ T cells, a human counterpart of murine NK1+ T cells, from normal subjects

I. Iwamoto, A. Sakamoto, Y. Kita, 1999 .

High Glucose-Induced Upregulation of Osteopontin Is Mediated via Rho/Rho Kinase Pathway in Cultured Rat Aortic Smooth Muscle Cells

H. Kawamura, K. Yokote, Kazuki Kobayashi, 2004, Arteriosclerosis, thrombosis, and vascular biology.

METABOLIC IMPROVEMENT AND ABDOMINAL FAT REDISTRIBUTION IN WERNER SYNDROME BY PIOGLITAZONE

H. Kawamura, K. Yokote, Kazuki Kobayashi, 2004, Journal of the American Geriatrics Society.

Toward the realization of a better aged society: Messages from gerontology and geriatrics

Hidenao Fukuyama, Toru Kita, Yasushi Saito, 2012, Geriatrics & gerontology international.

Effect of PPARalpha activation of macrophages on the secretion of inflammatory cytokines in cultured adipocytes.

H. Bujo, K. Murakami, H. Unoki, 2007, European journal of pharmacology.

Triglyceride-lowering effect of pitvastatin in a rat model of postprandial lipemia

M. Kitahara, T. Tamaki, Yasushi Saito, 2002 .

Stat5a Inhibits IL-12-Induced Th1 Cell Differentiation through the Induction of Suppressor of Cytokine Signaling 3 Expression1

M. Kubo, A. Yoshimura, Kotaro Suzuki, 2005, The Journal of Immunology.

Genetic association of low-density lipoprotein receptor-related protein 2 (LRP2) with plasma lipid levels.

T. Nakajima, M. Emi, H. Bujo, 2007, Journal of atherosclerosis and thrombosis.

Hypercholesterolemia associated with splice-junction variation of inter-α-trypsin inhibitor heavy chain 4 (ITIH4) gene

M. Emi, Y. Ezura, H. Bujo, 2004, Journal of Human Genetics.

In vivo overexpression of CTLA‐4 suppresses lymphoproliferative diseases and thymic negative selection

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