Christian Gassner

发表

Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies

Guy Georges, Werner Scheuer, Wolfgang Schaefer, 2011, Proceedings of the National Academy of Sciences.

Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain

C. Klein, Markus Thomas, H. Kettenberger, 2013, PloS one.

Oxidative Protein Folding Is Driven by the Electron Transport System

M. Bader, J. Bardwell, D. Ballou, 1999, Cell.

Ang-2-VEGF-A CrossMab, a Novel Bispecific Human IgG1 Antibody Blocking VEGF-A and Ang-2 Functions Simultaneously, Mediates Potent Antitumor, Antiangiogenic, and Antimetastatic Efficacy

Y. Kienast, Markus Thomas, H. Augustin, 2013, Clinical Cancer Research.

A Novel Angiopoietin-2 Selective Fully Human Antibody with Potent Anti-Tumoral and Anti-Angiogenic Efficacy and Superior Side Effect Profile Compared to Pan-Angiopoietin-1/-2 Inhibitors

Y. Kienast, C. Klein, Markus Thomas, 2013, PloS one.

Cancer Therapy : Preclinical Ang-2-VEGF-A CrossMab , a Novel Bispeci fi c Human IgG 1 Antibody Blocking VEGF-A and Ang-2 Functions Simultaneously , Mediates Potent Antitumor , Antiangiogenic , and Antimetastatic Ef fi cacy

Y. Kienast, C. Klein, Markus Thomas, 2013 .

Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC specific T-cell bispecific antibody.

C. Klein, B. Vick, I. Jeremias, 2021, Blood.

Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition.

C. Klein, U. Brinkmann, C. Ries, 2012, Archives of biochemistry and biophysics.

Bispecific antibody derivatives with restricted binding functionalities that are activated by proteolytic processing

U. Brinkmann, B. Bossenmaier, Wilma Lau, 2012, Protein engineering, design & selection : PEDS.

Ang-2-vegf-a Crossmab, a Novel Bispecific Human Igg1 Antibody Blocking Vegf-a and Ang-2 Functions Simultaneously, Mediates Potent Anti-tumor, Anti-angiogenic, and Anti-metastatic Efficacy Financial Disclosure Translational Relevance on Lc06, an Ang-2 Selective Human Igg1 Antibody. the Potency of Ang

Y. Kienast, Markus Thomas, H. Augustin, 2022 .

GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecific IgG1 antibodies

M. Mølhøj, O. Tyshchuk, C. Gassner, 2017, mAbs.

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

C. Klein, U. Brinkmann, A. Graff-Meyer, 2019, mAbs.