Leanne Mackin

Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine.

H. Thomas, T. Kay, A. Luster, 2023, Journal of autoimmunity.

Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice

H. Thomas, T. Kay, K. Graham, 2021, Diabetologia.

Disruption of Serinc1, which facilitates serine‐derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility

K. Gaus, H. Thomas, T. Kay, 2017, Molecular immunology.

Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse.

L. Boon, H. Thomas, T. Kay, 2022, Cell reports.

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon–Dependent Pathway

J. Trapani, P. Bird, Z. Mollah, 2017, Diabetes.

Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes

S. Bröer, C. Elso, T. Brodnicki, 2015, G3: Genes, Genomes, Genetics.

A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility.

T. Speed, G. Smyth, G. Morahan, 2010, Genome research.