Luann Zerefa

Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects

C. Paweletz, M. Ficial, B. Piel, 2024, Molecular cancer.

Abstract 886: Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects

C. Paweletz, Catherine J. Wu, S. Signoretti, 2023, Cancer Research.

Abstract 2814: Anti-CAIX Immune Restoring (IR) CAR-T cells display superior antitumor activity and reverse immunosuppressive TME in a humanized ccRCC orthotopic mouse model

Kristen L Jones, C. Paweletz, S. Signoretti, 2022, Cancer Research.