Pier Paolo Pandolfi

发表

Nuclear dynamics of PML for c-Jun transcriptional regulation in response to DNA damage.

Paolo Salomoni, Rosa Bernardi, A Changuo, 2002 .

PML is required for the ability of DAXX to regulate programmed cell death.

Paolo Salomoni, Pier Paolo Pandolfi, Ailan Guo, 1999 .

The Mouse Hospital and Its Integration in Ultra-Precision Approaches to Cancer Care

Pier Paolo Pandolfi, John G. Clohessy, J. Clohessy, 2018, Front. Oncol..

PML modulates p73-dependent transcription and apoptosis.

Pier Paolo Pandolfi, Francesca Bernassola, Paolo Salomoni, 2001 .

PML enhances p73 transcriptional activity and biological functions by preventing its proteasome-dependent degradation

Pier Paolo Pandolfi, Francesca Bernassola, Paolo Salomoni, 2002 .

A Dialog on the First 20 Years of PML Research and the Next 20 Ahead

Rosa Bernardi, Pier Paolo Pandolfi, P. Pandolfi, 2014, Front. Oncol..

PML targeting eradicates quiescent leukaemia-initiating cells

Yasuo Ikeda, Rosa Bernardi, Pier Paolo Pandolfi, 2008, Nature.

The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice.

Pier Paolo Pandolfi, Michel Cohen-Tannoudji, P. Pandolfi, 2005, Developmental cell.

Role of Promyelocytic Leukemia (Pml) Sumolation in Nuclear Body Formation, 11s Proteasome Recruitment, and as2O3-Induced Pml or Pml/Retinoic Acid Receptor α Degradation

Paul Freemont, Pier Paolo Pandolfi, P. Pandolfi, 2001, The Journal of experimental medicine.

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

Pier Paolo Pandolfi, Arkaitz Carracedo, P. Pandolfi, 2008, Nature.

The mechanisms of PML-nuclear body formation.

Pier Paolo Pandolfi, Hui-Kuan Lin, P. Pandolfi, 2006, Molecular cell.

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.

Rosa Bernardi, Pier Paolo Pandolfi, Carlos Cordon-Cardo, 2006, Nature.

TSPYL5 suppresses p53 levels and function by physical interaction with USP7

René Bernards, Pier Paolo Pandolfi, Oscar Krijgsman, 2011, Nature Cell Biology.

Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

Ferdinando Di Cunto, Judy Lieberman, Ugo Ala, 2011, Cell.

Tenets of PTEN Tumor Suppression

Pier Paolo Pandolfi, Arkaitz Carracedo, P. Pandolfi, 2008, Cell.

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Pier Paolo Pandolfi, Pier Giuseppe Pelicci, Ettore Appella, 2000, Nature.

Subtle variations in Pten dose determine cancer susceptibility

Pier Paolo Pandolfi, Arkaitz Carracedo, Edi Brogi, 2010, Nature Genetics.

Nucleophosmin and cancer

Pier Paolo Pandolfi, Brunangelo Falini, P. Pandolfi, 2006, Nature Reviews Cancer.

Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development

Pier Paolo Pandolfi, Lee Niswander, Maria Barna, 2005, Nature.

Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain

Pier Paolo Pandolfi, Annalisa Canta, Annamaria Vezzani, 2004, Development.

The Promyelocytic Leukemia Protein Protects p53 from Mdm2-mediated Inhibition and Degradation*

Pier Paolo Pandolfi, P. Pandolfi, Ronit Vogt Sionov, 2003, Journal of Biological Chemistry.

PTEN and p53: who will get the upper hand?

Pier Paolo Pandolfi, P. Pandolfi, L. Trotman, 2003, Cancer cell.

Cytoplasmic PML function in TGF-beta signalling.

Pier Paolo Pandolfi, Hui-Kuan Lin, P. Pandolfi, 2004, Nature.

Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach

Kourosh Zarringhalam, Rahul V. Kulkarni, Pier Paolo Pandolfi, 2017, Scientific Reports.

The Multiple Roles of PTEN in Tumor Suppression

Pier Paolo Pandolfi, P. Pandolfi, Antonio Di Cristofano, 2000, Cell.

Mitochondrial Basis for Immune Deficiency: Evidence from Purine Nucleoside Phosphorylase–Deficient Mice

Pier Paolo Pandolfi, P. Pandolfi, M. Hershfield, 2000 .

The transcriptional role of PML and the nuclear body

Pier Paolo Pandolfi, Sue Zhong, Paolo Salomoni, 2000, Nature Cell Biology.

From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition

Cristian Loretelli, Pier Paolo Pandolfi, P. Pandolfi, 2013, Nature Structural &Molecular Biology.

The APL paradigm and the "co-clinical trial" project.

Lewis C Cantley, Pier Paolo Pandolfi, Caterina Nardella, 2011, Cancer discovery.

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

Andrew L. Kung, Matthew D. Wilkerson, Michael D. Cameron, 2012, Nature.

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

Ugo Ala, Pier Paolo Pandolfi, Andrea L. Richardson, 2013, Cell.

The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.

Brian Seed, Pier Paolo Pandolfi, R. Xavier, 2016, Cell reports.

Identification of a tumour suppressor network opposing nuclear Akt function

Jason A. Koutcher, Pier Paolo Pandolfi, Carlos Cordon-Cardo, 2006, Nature.

Phosphorylation and Functional Inactivation of TSC2 by Erk Implications for Tuberous Sclerosisand Cancer Pathogenesis

Paul Tempst, Pier Paolo Pandolfi, Hediye Erdjument-Bromage, 2005, Cell.

The Role of PML in Tumor Suppression

Pier Paolo Pandolfi, Paolo Salomoni, P. Pandolfi, 2002, Cell.

NPM mutations in acute myelogenous leukemia.

Pier Paolo Pandolfi, P. Pandolfi, Silvia Grisendi, 2005, The New England journal of medicine.

PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts

Pier Paolo Pandolfi, Paolo Salomoni, P. Pandolfi, 2005, Oncogene.

Signaling control of mRNA translation in cancer pathogenesis

Nahum Sonenberg, Pier Paolo Pandolfi, George Thomas, 2004, Oncogene.

Assessing the construct validity of the Italian version of the EQ-5D: preliminary results from a cross-sectional study in North Italy

Maria Pia Fantini, Pier Paolo Pandolfi, Elena Savoia, 2006, Health and quality of life outcomes.

The p66shc adaptor protein controls oxidative stress response and life span in mammals

Pier Paolo Pandolfi, Pier Giuseppe Pelicci, Marco Giorgio, 1999, Nature.

ceRNA cross-talk in cancer: when ce-bling rivalries go awry.

Pier Paolo Pandolfi, P. Pandolfi, F. Karreth, 2013, Cancer discovery.

PML regulates p53 stability by sequestering Mdm2 to the nucleolus

Rosa Bernardi, Pier Paolo Pandolfi, Karen H. Vousden, 2004, Nature Cell Biology.

Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression

Tom Misteli, Paul Tempst, Xuejun Jiang, 2007, Cell.

Aberrant mRNA translation in cancer pathogenesis: an old concept revisited comes finally of age

Pier Paolo Pandolfi, P. Pandolfi, 2004, Oncogene.

Dyskeratosis Congenita and Cancer in Mice Deficient in Ribosomal RNA Modification

Francesco Piazza, Pier Paolo Pandolfi, Davide Ruggero, 2003, Science.

Role of LRF/Pokemon in lineage fate decisions.

Pier Paolo Pandolfi, P. Pandolfi, A. Lunardi, 2013, Blood.

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

Pier Paolo Pandolfi, Mark J. Walport, H. Terence Cook, 1998, Nature Genetics.

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

James Douglas Engel, Pier Paolo Pandolfi, J. D. Engel, 1995, Nature Genetics.

The PTEN–PI3K pathway: of feedbacks and cross-talks

Pier Paolo Pandolfi, Arkaitz Carracedo, P. Pandolfi, 2008, Oncogene.

Cancer metabolism: fatty acid oxidation in the limelight

Pier Paolo Pandolfi, Arkaitz Carracedo, Lewis C. Cantley, 2013, Nature Reviews Cancer.

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Jason A. Koutcher, Howard I. Scher, Pier Paolo Pandolfi, 2005, Nature.

The TLX1 oncogene drives aneuploidy in T-cell transformation

Andrea Califano, Frank Speleman, Susana Raimondi, 2010, Nature Medicine.

Tsc2-Rheb Signaling Regulates EphA-Mediated Axon Guidance

Mustafa Sahin, Pier Paolo Pandolfi, Elena B. Pasquale, 2009, Nature Neuroscience.

Characterization of dual PTEN and p53-targeting microRNAs identifies microRNA-638/Dnm2 as a two-hit oncogenic locus.

Judy Lieberman, Pier Paolo Pandolfi, J. Lieberman, 2014, Cell reports.

PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR

Rosa Bernardi, Pier Paolo Pandolfi, Carlos Cordon-Cardo, 2006, Nature.

Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1.

Seiji Fukuda, Pier Paolo Pandolfi, P. Pandolfi, 2005, Blood.

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

Laurence A. Turka, Paolo Pinton, Pier Paolo Pandolfi, 2014, Cell.

The function of PML in p53-dependent apoptosis

Ailan Guo, Alan Shih, Pier Paolo Pandolfi, 2000, Nature Cell Biology.

PML Activates Transcription by Protecting HIPK2 and p300 from SCFFbx3-Mediated Degradation

Tomoki Chiba, Pier Paolo Pandolfi, Tatsuro Irimura, 2008, Molecular and Cellular Biology.

Mitochondrial Basis for Immune Deficiency

Pier Paolo Pandolfi, Michael Hershfield, P. Pandolfi, 2000, The Journal of experimental medicine.

Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation

Pier Paolo Pandolfi, P. Pandolfi, L. Salmena, 2007, Nature Reviews Cancer.

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

Jing Wang, Chia-Hsin Chan, Pier Paolo Pandolfi, 2010, Nature.

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

Rosa Bernardi, Pier Paolo Pandolfi, P. Pandolfi, 2007, Nature Reviews Molecular Cell Biology.

The mechanisms of PML-nuclear body formation.

Pier Paolo Pandolfi, Hui-Kuan Lin, P. Pandolfi, 2006, Molecular cell.

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

Pier Paolo Pandolfi, Carlos Cordon-Cardo, Arkaitz Carracedo, 2009, Nature Genetics.

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

Pier Paolo Pandolfi, Arkaitz Carracedo, Su Jung Song, 2011, Cell.