Francis X Guyette

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Reduced Cleavage of Von Willebrand Factor By ADAMTS13 Exacerbates Acute Kidney Injury Secondary to Traumatic Injury

J. Sperry, M. Neal, B. Zuckerbraun, 2020 .

Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses

Upendra K. Kar, S. Wisniewski, A. Cyr, 2021, Cell reports. Medicine.

A Systemic Storm in Critically Injured Humans Revealed by Longitudinal Multi-Omics

Upendra K. Kar, S. Wisniewski, A. Cyr, 2021 .

Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness

Upendra K. Kar, C. Callaway, A. Cyr, 2021, Nature Communications.

External validation of the Air Medical Prehospital Triage score for identifying trauma patients likely to benefit from scene helicopter transport

A. Peitzman, F. Guyette, M. Rosengart, 2017, The journal of trauma and acute care surgery.

Development and Validation of the Air Medical Prehospital Triage Score for Helicopter Transport of Trauma Patients

A. Peitzman, F. Guyette, M. Rosengart, 2016, Annals of surgery.

Helicopter transport improves survival following injury in the absence of a time-saving advantage.

A. Peitzman, F. Guyette, M. Rosengart, 2016, Surgery.

Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps

A. Peitzman, F. Guyette, J. Sperry, 2015, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

Evaluation of critical care burden following traumatic injury from two randomized controlled trials

F. Guyette, J. Sperry, B. Harbrecht, 2023, Scientific Reports.

Early Prehospital Tranexamic Acid Following Injury Is Associated With a 30-day Survival Benefit

F. Guyette, J. Sperry, Joshua B. Brown, 2021, Annals of surgery.

Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial.

C. Callaway, A. Peitzman, D. Yealy, 2020, JAMA surgery.

Traumatic injury results in prolonged circulation of ultralarge von Willebrand factor and a reduction in ADAMTS13 activity

F. Guyette, J. Sperry, M. Neal, 2020, Transfusion.

FORGOT CALCIUM? ADMISSION IONIZED-CALCIUM IN TWO CIVILIAN RANDOMIZED CONTROLLED TRIALS OF PRE-HOSPITAL PLASMA FOR TRAUMATIC HEMORRHAGIC SHOCK.

A. Sauaia, F. Guyette, J. Sperry, 2020, The journal of trauma and acute care surgery.

Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials.

James G. Chandler, A. Sauaia, F. Guyette, 2019, JAMA surgery.

Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

C. Callaway, A. Peitzman, D. Yealy, 2018, The New England journal of medicine.

Lactate as a mediator of prehospital plasma mortality reduction in hemorrhagic shock

F. Guyette, J. Sperry, B. Harbrecht, 2021, The journal of trauma and acute care surgery.

Identifying patients with time-sensitive injuries: Association of mortality with increasing prehospital time

A. Peitzman, F. Guyette, J. Sperry, 2019, The journal of trauma and acute care surgery.

Pre-trauma center red blood cell transfusion is associated with improved early outcomes in air medical trauma patients.

A. Peitzman, F. Guyette, J. Sperry, 2015, Journal of the American College of Surgeons.

Prehospital lactate improves accuracy of prehospital criteria for designating trauma activation level

E. Lerner, A. Peitzman, F. Guyette, 2016, The journal of trauma and acute care surgery.

Prehospital Lactate is Associated with the Need for Blood in Trauma

Samuel M. Galvagno, F. Guyette, Joshua B. Brown, 2021, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

Early Cold Stored Platelet Transfusion Following Severe Injury

E. Fox, L. Kornblith, Bedda L. Rosario-Rivera, 2024, Annals of surgery.

Taking the Blood Bank to the Field: The Design and Rationale of the Prehospital Air Medical Plasma (PAMPer) Trial

A. Peitzman, F. Guyette, J. Sperry, 2015, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

Prehospital synergy: Tranexamic acid and blood transfusion in patients at risk for hemorrhage

F. Guyette, J. Sperry, Joshua B. Brown, 2022, The journal of trauma and acute care surgery.

Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial.

A. Peitzman, F. Guyette, J. Sperry, 2019, Annals of surgery.

The Effect of Blood Transfusion during Air Medical Transport on Transport Times in Patients with Ruptured Abdominal Aortic Aneurysm

F. Guyette, N. Liang, Nancy Mikati, 2021, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

Massive transfusion and the response to prehospital plasma: It is all in how you define it

F. Guyette, J. Sperry, B. Harbrecht, 2020, The journal of trauma and acute care surgery.

Evaluating the Cost-effectiveness of Prehospital Plasma Transfusion in Unstable Trauma Patients: A Secondary Analysis of the PAMPer Trial.

F. Guyette, J. Sperry, B. Harbrecht, 2021, JAMA surgery.

Developing a National Trauma Research Action Plan: Results from the prehospital and mass casualty research Delphi survey

Pam J Bixby, E. Lerner, N. Mann, 2021, The journal of trauma and acute care surgery.

Prehospital plasma in injured patients is associated with survival principally in blunt injury: Results from two randomized prehospital plasma trials

A. Sauaia, F. Guyette, J. Sperry, 2019, The journal of trauma and acute care surgery.