Karina Orlowska

发表

Dioxin-elicited decrease in cobalamin redirects propionyl-CoA metabolism to the β–oxidation-like pathway resulting in acrylyl-CoA conjugate buildup

Anthony L. Schilmiller, T. Zacharewski, A. Schilmiller, 2022, The Journal of biological chemistry.

Dioxin-elicited decrease in cobalamin redirects hepatic propionyl-CoA metabolism to the β–oxidation-like pathway resulting in acrylyl-CoA conjugate accumulation

Anthony L. Schilmiller, T. Zacharewski, A. Schilmiller, 2022, bioRxiv.

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells

A. Sadowska, A. Nynca, K. Orlowska, 2020, PeerJ.

Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver

T. Zacharewski, R. Nault, K. Orlowska, 2023, Scientific Reports.

Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer

I. Otrocka-Domagała, A. Sadowska, A. Nynca, 2023, BMC Genomics.

Cystine/Glutamate Xc– Antiporter Induction Compensates for Transsulfuration Pathway Repression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) to Ensure Cysteine for Hepatic Glutathione Biosynthesis

Anthony L. Schilmiller, T. Zacharewski, A. Schilmiller, 2023, Chemical research in toxicology.

2,3,7,8-Tetrachlorodibenzo-p-dioxin elicited decreases in cobalamin inhibits methylmalonyl-CoA mutase activity redirecting propionyl-CoA metabolism to the β–oxidation-like pathway resulting in hepatic accumulation of the toxic intermediate acrylyl-CoA

T. Zacharewski, R. Nault, K. Orlowska, 2021 .

Identification and characterization of long non-coding RNAs in porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

A. Sadowska, A. Nynca, K. Orlowska, 2018, Journal of Animal Science and Biotechnology.

Is CYP1B1 involved in the metabolism of dioxins in the pig?

A. Sadowska, A. Nynca, K. Orlowska, 2019, Biochimica et biophysica acta. General subjects.

Structural-functional adaptations of porcine CYP1A1 to metabolize polychlorinated dibenzo-p-dioxins.

A. Sadowska, Tomasz Molcan, Sylwia Swigonska, 2017, Chemosphere.

The tertiary structures of porcine AhR and ARNT proteins and molecular interactions within the TCDD/AhR/ARNT complex.

A. Sadowska, A. Nynca, R. Ciereszko, 2016, Journal of molecular graphics & modelling.