Xiang‐Jin Meng

P. Halbur, P. Paul, J. J. Andrews, 1996, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

Origin, Evolution, and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States

Li Fang, Allan W. Dickerman, T. Opriessnig, 2013, mBio.

ISG15 Modulates Type I Interferon Signaling and the Antiviral Response during Hepatitis E Virus Replication

Dianjun Cao, Harini Sooryanarain, M. E. Haac, 2017, Journal of Virology.

An SH3 binding motif within the nucleocapsid protein of porcine reproductive and respiratory syndrome virus interacts with the host cellular signaling proteins STAMI, TXK, Fyn, Hck, and cortactin.

X. Meng, S. Kenney, Scott P. Kenney, 2015, Virus research.

Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+CD8+ T, CD8+ T, and γδ T cell responses.

T. Opriessnig, D. Tian, Qian M Cao, 2019, Virology.

Differences in susceptibility of Duroc, Hampshire, and Meishan pigs to infection with a high virulence strain (VR2385) of porcine reproductive and respiratory syndrome virus (PRRSV)

P. Halbur, M. Rothschild, Xiang‐Jin Meng, 1998 .

Porcine circovirus type 2 (PCV2): pathogenesis and interaction with the immune system.

X. Meng, Xiang‐Jin Meng, 2013, Annual review of animal biosciences.

Porcine Circovirus Type 2–Associated Disease: Update on Current Terminology, Clinical Manifestations, Pathogenesis, Diagnosis, and Intervention Strategies

T. Opriessnig, P. Halbur, X. Meng, 2007, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

Ten years of PCV2 vaccines and vaccination: Is eradication a possibility?

Z. Afghah, S. Ramamoorthy, B. Webb, 2017, Veterinary microbiology.

A commercial porcine circovirus (PCV) type 2a-based vaccine reduces PCV2d viremia and shedding and prevents PCV2d transmission to naïve pigs under experimental conditions

T. Opriessnig, P. Halbur, P. Gerber, 2017, Vaccine.

Mutant USA strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarean-derived, colostrum-deprived pigs

T. Opriessnig, P. Halbur, P. Gerber, 2014, The Journal of general virology.

Commercial PCV2a-based vaccines are effective in protecting naturally PCV2b-infected finisher pigs against experimental challenge with a 2012 mutant PCV2.

T. Opriessnig, P. Halbur, P. Gerber, 2014, Vaccine.

A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection.

T. Opriessnig, P. Halbur, P. Gerber, 2013, Vaccine.

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2).

N. M. Beach, X. Meng, Xiang‐Jin Meng, 2012, Virus research.

Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtypes in pigs.

T. Opriessnig, S. Wu, N. M. Beach, 2010, Vaccine.

Comparison of the effectiveness of passive (dam) versus active (piglet) immunization against porcine circovirus type 2 (PCV2) and impact of passively derived PCV2 vaccine-induced immunity on vaccination.

T. Opriessnig, P. Halbur, D. Madson, 2010, Veterinary microbiology.

Effect of Porcine Circovirus Type 2 (PCV2) Vaccination of the Dam on PCV2 Replication In Utero

T. Opriessnig, D. Madson, X. Meng, 2009, Clinical and Vaccine Immunology.

Infectivity of porcine circovirus type 2 DNA in semen from experimentally-infected boars

T. Opriessnig, P. Halbur, D. Madson, 2008, Veterinary research.

Influence of Maternal Antibodies on Efficacy of Porcine Circovirus Type 2 (PCV2) Vaccination To Protect Pigs from Experimental Infection with PCV2

T. Opriessnig, P. Halbur, X. Meng, 2007, Clinical and Vaccine Immunology.

A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV Type 2 (PCV2) Cloned into the Genomic Backbone of the Nonpathogenic PCV1 Induces Protective Immunity against PCV2 Infection in Pigs

T. Opriessnig, P. Halbur, M. Fenaux, 2004, Journal of Virology.

A live-attenuated and an inactivated chimeric porcine circovirus (PCV)1-2 vaccine are both effective at inducing a humoral immune response and reducing PCV2 viremia and intrauterine infection in female swine of breeding age.

T. Opriessnig, P. Halbur, Chong Wang, 2014, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

Comparison of Three Enzyme-Linked Immunosorbent Assays to Detect Porcine Circovirus-2 (PCV-2)—Specific Antibodies after Vaccination or Inoculation of Pigs with Distinct PCV-1 or PCV-2 Isolates

T. Opriessnig, P. Halbur, S. Ramamoorthy, 2008, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

The PD-L1/CD86 ratio is increased in dendritic cells co-infected with porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus, and the PD-L1/PD-1 axis is associated with anergy, apoptosis, and the induction of regulatory T-cells in porcine lymphocytes.

S. Todd, T. Cecere, O. Richmond, 2015, Veterinary microbiology.

Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer.

D. A. Stein, T. Opriessnig, P. Halbur, 2011, Antiviral research.

Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity

Dianjun Cao, D. Tian, C. Overend, 2017, Proceedings of the National Academy of Sciences.

Zoonotic origin of hepatitis E.

Xiang‐Jin Meng, N. Pavio, V. Doceul, 2015, Current opinion in virology.

Consensus proposals for classification of the family Hepeviridae

P. Simmonds, S. Emerson, M. Purdy, 2014, The Journal of general virology.

Association of hepatitis E virus (HEV) and postweaning multisystemic wasting syndrome (PMWS) with lesions of hepatitis in pigs.

J. Segalés, N. de Deus, E. Mateu, 2007, Veterinary microbiology.

Routes of Transmission of Swine Hepatitis E Virus in Pigs

P. Halbur, D. Guenette, C. Kasorndorkbua, 2004, Journal of Clinical Microbiology.

Evidence of Extrahepatic Sites of Replication of the Hepatitis E Virus in a Swine Model

P. Halbur, X. Meng, G. Haqshenas, 2001, Journal of Clinical Microbiology.

Comparative Pathogenesis of Infection of Pigs with Hepatitis E Viruses Recovered from a Pig and a Human

S. Emerson, R. Purcell, P. Halbur, 2001, Journal of Clinical Microbiology.

Proposed reference sequences for hepatitis E virus subtypes.

P. Simmonds, M. Purdy, J. Izopet, 2016, The Journal of general virology.

Recent advances in Hepatitis E Virus

X. Meng, X. Meng, Xiang‐Jin Meng, 2010, Journal of viral hepatitis.

A broadly reactive one-step real-time RT-PCR assay for rapid and sensitive detection of hepatitis E virus.

B. Robertson, V. Hill, X. Meng, 2006, Journal of virological methods.

Hepatitis E virus: reasons for emergence in humans.

Harini Sooryanarain, X. Meng, Xiang‐Jin Meng, 2019, Current opinion in virology.

Update: proposed reference sequences for subtypes of hepatitis E virus (species Orthohepevirus A)

P. Simmonds, M. Purdy, J. Izopet, 2020, The Journal of general virology.

Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model

T. Opriessnig, P. Halbur, N. M. Beach, 2012, Veterinary Research Communications.

Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries

S. Emerson, R. Purcell, B. Wiseman, 2002, Journal of Clinical Microbiology.

Recombinant Porcine Reproductive and Respiratory Syndrome Virus Expressing Membrane-Bound Interleukin-15 as an Immunomodulatory Adjuvant Enhances NK and γδ T Cell Responses and Confers Heterologous Protection

P. Roberts, Dianjun Cao, D. Tian, 2018, Journal of Virology.

Wild boars as sources for infectious diseases in livestock and humans

D. Lindsay, X. Meng, N. Sriranganathan, 2009, Philosophical Transactions of the Royal Society B: Biological Sciences.

Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.

S. Emerson, R. Purcell, F. Pierson, 2004, The Journal of general virology.

The putative capsid protein of the newly identified avian hepatitis E virus shares antigenic epitopes with that of swine and human hepatitis E viruses and chicken big liver and spleen disease virus.

M. Fenaux, F. Pierson, X. Meng, 2002, The Journal of general virology.

Evidence that the Genomic RNA of Hepatitis E Virus Is Capped

S. Emerson, R. Purcell, Y. Kabrane-Lazizi, 1999, Journal of Virology.

Genetic and Experimental Evidence for Cross-Species Infection by Swine Hepatitis E Virus

M. Shapiro, S. Emerson, R. Purcell, 1998, Journal of Virology.

Identification of B-cell epitopes in the capsid protein of avian hepatitis E virus (avian HEV) that are common to human and swine HEVs or unique to avian HEV.

P. Halbur, E. Zhou, X. Meng, 2006, The Journal of general virology.

CD8+ lymphocytes but not B lymphocytes are required for protection against chronic hepatitis E virus infection in chickens

Danielle M. Yugo, Shannon R. Matzinger, C. L. Heffron, 2019, Journal of medical virology.

A trivalent vaccine candidate against hepatitis E virus, norovirus, and astrovirus.

Dianjun Cao, M. Xia, Xi Jiang, 2016, Vaccine.

A dual vaccine candidate against norovirus and hepatitis E virus.

Dianjun Cao, Xi Jiang, M. Tan, 2014, Vaccine.

Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs.

T. Opriessnig, Yao-Wei Huang, C. Cossaboom, 2012, The Journal of general virology.

Molecular biology and replication of hepatitis E virus

Dianjun Cao, X. Meng, Xiang‐Jin Meng, 2012, Emerging Microbes & Infections.

Three Amino Acid Mutations (F51L, T59A, and S390L) in the Capsid Protein of the Hepatitis E Virus Collectively Contribute to Virus Attenuation

S. Emerson, T. Opriessnig, Yao-Wei Huang, 2011, Journal of Virology.

Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs.

S. Emerson, Yao-Wei Huang, T. LeRoith, 2011, Virus research.

Hepatitis E Virus Genome Structure and Replication Strategy.

X. Meng, S. Kenney, Scott P. Kenney, 2019, Cold Spring Harbor perspectives in medicine.

Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population

S. Emerson, R. Purcell, Y. Zhang, 1999, Journal of medical virology.

The PSAP Motif within the ORF3 Protein of an Avian Strain of the Hepatitis E Virus Is Not Critical for Viral Infectivity In Vivo but Plays a Role in Virus Release

Yao-Wei Huang, T. LeRoith, F. Pierson, 2012, Journal of Virology.