Xiaoli Meng

发表

Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine

M. Pirmohamed, A. Marson, B. K. Park, 2020, British journal of clinical pharmacology.

The importance of hapten–protein complex formation in the development of drug allergy

B. K. Park, D. Naisbitt, L. Faulkner, 2014, Current opinion in allergy and clinical immunology.

In-Vitro Approaches to Predict and Study T-Cell Mediated Hypersensitivity to Drugs

D. Naisbitt, X. Meng, Sean L. Hammond, 2021, Frontiers in Immunology.

Drug hapten‐specific T‐cell activation: Current status and unanswered questions

D. Naisbitt, X. Meng, Kareena Adair, 2021, Proteomics.

Identification of flucloxacillin-haptenated HLA-B*57:01 ligands: evidence of antigen processing and presentation.

A. Purcell, D. Naisbitt, R. Jenkins, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis

M. Pirmohamed, B. K. Park, D. Naisbitt, 2011, The Journal of Immunology.

HLA Class II-restricted CD8+ T cells contribute to the promiscuous immune response in dapsone hypersensitive patients.

M. Pirmohamed, Jianjun Liu, Hong Liu, 2021, The Journal of investigative dermatology.

Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B*13:01

Andrew Gibson, Jianjun Liu, Hong Liu, 2019, Allergy.

Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors.

D. Naisbitt, M. Ogese, J. Maggs, 2017, Chemical research in toxicology.

What’s been Hapten-ing over the last 88 years?

D. Naisbitt, X. Meng, Sean Hammond, 2023, Medicinal Chemistry Research.

Characterization of amoxicillin and clavulanic acid specific T‐cell clones from patients with immediate drug hypersensitivity

D. Naisbitt, M. Ogese, M. Torres, 2020, Allergy.

Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients

M. Pirmohamed, B. K. Park, D. Naisbitt, 2011, Journal of Pharmacology and Experimental Therapeutics.

Characterisation of flucloxacillin and 5‐hydroxymethyl flucloxacillin haptenated HSA in vitro and in vivo

M. Pirmohamed, N. Kitteringham, B. K. Park, 2009, Proteomics. Clinical applications.

Patients with naproxen‐induced liver injury display T‐cell memory responses toward an oxidative (S)‐O‐desmethyl naproxen metabolite but not the acyl glucuronide

M. Pirmohamed, A. Odermatt, G. Aithal, 2023, Allergy.

Detection of Hepatic Drug Metabolite-Specific T-Cell Responses Using a Human Hepatocyte, Immune Cell Coculture System

Hong Liu, Yonghu Sun, Furen Zhang, 2023, Chemical research in toxicology.

Activation of human CD8+ T-cells with nitroso dapsone-modified HLA-B*13:01-binding peptides

M. Pirmohamed, Hong Liu, Yonghu Sun, 2023, Journal of immunology.

Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01

M. Pirmohamed, A. Lister, B. K. Park, 2021, Toxicological sciences : an official journal of the Society of Toxicology.

Cell Membrane Transporters Facilitate the Accumulation of Hepatocellular Flucloxacillin Protein Adducts: Implication in Flucloxacillin-Induced Liver Injury.

Amy E. Chadwick, B. K. Park, D. Naisbitt, 2020, Chemical research in toxicology.

Drug‐specific T‐cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat

D. Naisbitt, L. Leclercq, A. de Bondt, 2020, Allergy.

Characterization of Clozapine-Responsive Human T Cells

M. Pirmohamed, B. K. Park, D. Naisbitt, 2020, The Journal of Immunology.

HLA DRB1*15:01-DQB1*06:02-restricted human CD4+ T-cells are selectively activated with amoxicillin-peptide adducts.

M. Pirmohamed, B. K. Park, D. Naisbitt, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Definition of the Chemical and Immunological Signals Involved in Drug-induced Liver Injury.

B. K. Park, X. Meng, Kevin B. Park, 2020, Chemical research in toxicology.

Immune dysregulation increases the incidence of delayed‐type drug hypersensitivity reactions

Andrew Gibson, D. Naisbitt, M. Ogese, 2019, Allergy.

Exosomal Transport of Hepatocyte‐Derived Drug‐Modified Proteins to the Immune System

N. Kitteringham, B. K. Park, C. Goldring, 2019, Hepatology.

Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers

M. Monshouwer, B. K. Park, Andrew Gibson, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Mechanisms leading to T-cell activation in drug hypersensitivity

D. Naisbitt, X. Meng, D. Yerly, 2018, Current opinion in allergy and clinical immunology.

Immune drug-induced liver disease and drugs

B. K. Park, D. Naisbitt, X. Meng, 2017, Current Opinion in Toxicology.

Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients

B. K. Park, D. Naisbitt, R. Jenkins, 2017, The Journal of Immunology.

Promiscuous T-cell responses to drugs and drug-haptens.

M. Pirmohamed, B. K. Park, D. Naisbitt, 2015, The Journal of allergy and clinical immunology.

Characterization of the Antigen Specificity of T-Cell Clones from Piperacillin-Hypersensitive Patients with Cystic Fibrosis

M. Pirmohamed, B. K. Park, D. Naisbitt, 2012, Journal of Pharmacology and Experimental Therapeutics.

Detection of drug bioactivation in vivo: mechanism of nevirapine-albumin conjugate formation in patients.

B. K. Park, D. Naisbitt, R. Jenkins, 2013, Chemical research in toxicology.