S. Hughes

Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1

P. Boyer, S. Hughes, Stephen H. Hughes, 1995, Antimicrobial agents and chemotherapy.

The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.

S. Sarafianos, P. Boyer, S. Hughes, 2000, Journal of molecular biology.

Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site.

S. Sarafianos, P. Boyer, S. Hughes, 1999, Chemistry & biology.

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

P. Boyer, S. Hughes, E. Arnold, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.

A. D. Clark, Jianping Ding, S. Sarafianos, 1998, Journal of molecular biology.

Site-directed mutagenic analysis of viral polymerases and related proteins.

P. Boyer, S. Hughes, Stephen H. Hughes, 1996, Methods in enzymology.