Elizabeth Iorns

发表

PI3K independent activation of mTORC1 as a target in lapatinib-resistant ERBB2+ breast cancer cells

R. Landgraf, E. Iorns, M. Pegram, 2012, Breast Cancer Research and Treatment.

An open investigation of the reproducibility of cancer biology research

Brian A. Nosek, Elizabeth Iorns, Timothy M Errington, 2014, eLife.

A New Mouse Model for the Study of Human Breast Cancer Metastasis

Elizabeth Iorns, Jennifer Clarke, M. Lippman, 2012, PloS one.

FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer.

A. Ashworth, A. Tutt, J. Reis-Filho, 2010, Cancer research.

Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.

A. Ashworth, A. Tutt, T. Crook, 2008, Cancer cell.

Replication Study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Timothy M. Errington, J. Fallowfield, E. Iorns, 2018, eLife.

Rescue of tropomyosin deficiency in Drosophila and human cancer cells by synaptopodin reveals a role of tropomyosin α in RhoA stabilization

M. Lippman, E. Iorns, C. Faul, 2012, The EMBO journal.

Investigating the replicability of preclinical cancer biology

Timothy M. Errington, T. Errington, C. Soderberg, 2021, eLife.

Utilizing RNA interference to enhance cancer drug discovery

A. Ashworth, C. Lord, N. Turner, 2007, Nature Reviews Drug Discovery.

Tumor and Stem Cell Biology Cancer Research FGFR 1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

A. Ashworth, A. Tutt, J. Reis-Filho, 2010 .

Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology

Timothy M. Errington, Lynette R. Bower, T. Errington, 2021, eLife.

Challenges for assessing replicability in preclinical cancer biology

Timothy M. Errington, T. Errington, E. Iorns, 2021, eLife.

Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors

Timothy M. Errington, T. Errington, E. Iorns, 2014, eLife.

A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor

Elizabeth Iorns, Alan Ashworth, A. Ashworth, 2008, The EMBO journal.

Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets

Elizabeth Iorns, Jorge S. Reis-Filho, Alan Ashworth, 2009, PloS one.

Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization.

Elizabeth Iorns, Alan Ashworth, A. Ashworth, 2009, The Biochemical journal.

Identifying Modifiers of Tamoxifen Sensitivity Using High-Throughput Genetic and Chemical Screens

A. Ashworth, C. Lord, E. Iorns, 2009 .

Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor

A. Ashworth, M. Zvelebil, Dafydd G. Thomas, 2012, Breast Cancer Research and Treatment.

Proceedings of the 4th World Conference on Research Integrity

Logan L. Watts, James F. Johnson, Sophia Jui-An Pan, 2016, Research Integrity and Peer Review.

Replication Study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Timothy M. Errington, T. Errington, Jeewon Kim, 2018, eLife.

The role of SATB1 in breast cancer pathogenesis.

M. Lippman, E. Iorns, J. Clarke, 2010, Journal of the National Cancer Institute.

t he r ole of SAt B1 in Breast cancer Pathogenesis

M. Lippman, E. Iorns, J. Clarke, 2010 .

Next-Generation Sequencing for High-Throughput RNA Interference Screens

E. Iorns, T. Ward, A. Jegg, 2013 .

Registered report: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

Timothy M. Errington, T. Errington, E. Iorns, 2014, eLife.

Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Timothy M. Errington, T. Errington, H. Xin, 2019, eLife.

Distributed under Creative Commons Cc-by 4.0 Registered Report: Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

J. Fung, E. Iorns, A. Kosaka, 2022 .

Infiltrating S100A8+ myeloid cells promote metastatic spread of human breast cancer and predict poor clinical outcome

Dafydd G. Thomas, J. Reis-Filho, M. Lippman, 2014, Breast Cancer Research and Treatment.

Simultaneous analysis of tumor and stromal gene expression profiles from xenograft models

M. Lippman, E. Iorns, J. Clarke, 2011, Breast Cancer Research and Treatment.

Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

Timothy M. Errington, E. Iorns, N. Perfito, 2019, eLife.

Replication study: androgen receptor splice variants determine taxane sensitivity in prostate cancer

E. Iorns, Xiaochuan Shan, F. Aird, 2018, PeerJ.

Reproducibility Project: Cancer Biology

Tim Errington, Brian A. Nosek, Elizabeth Iorns, 2013 .