Onur Cil

发表

Benzopyrimido‐pyrrolo‐oxazine‐dione CFTR inhibitor (R)‐BPO‐27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins

A. Verkman, M. Donowitz, Jianyi Yin, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Repurposing calcium-sensing receptor activator drug cinacalcet for ADPKD treatment.

Parth D. Chhetri, P. Yottasan, T. Chu, 2023, Translational research : the journal of laboratory and clinical medicine.

Calcium-sensing receptor activator cinacalcet for treatment of cyclic nucleotide-mediated secretory diarrheas.

M. Donowitz, R. Lin, M. Tse, 2023, Translational research : the journal of laboratory and clinical medicine.

Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas

A. Verkman, O. Cil, Amber A. Rivera, 2021, JCI insight.

Magnesium for disease treatment and prevention: emerging mechanisms and opportunities.

Onur Cil, Qi Gao, 2024, Trends in pharmacological sciences.

Calcium-Sensing Receptor (CaSR) Modulates Ocular Surface Chloride Transport and Its Inhibition Promotes Ocular Surface Hydration.

A. Verkman, Neel D. Pasricha, P. Yottasan, 2024, The ocular surface.

Lubiprostone is a Non-Selective Activator of cAMP-Gated Ion Channels and Chloride Channel Protein 2 (Clc-2) Has a Minor Role in its Prosecretory Effect in Intestinal Epithelial Cells

J. Du Bois, O. Cil, Parth D. Chhetri, 2022, Molecular Pharmacology.

Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells

Parth D. Chhetri, Qianwen Chu, Onur Cil, 2023, The Journal of clinical investigation.

Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar‐potency inhibitor of calcium‐activated chloride channel TMEM16A

Youngho Seo, A. Verkman, J. Turner, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation

L. Galietta, A. Verkman, M. Donowitz, 2017, Translational research : the journal of laboratory and clinical medicine.

CFTR Activator Increases Intestinal Fluid Secretion and Normalizes Stool Output in a Mouse Model of Constipation

T. Ma, A. Verkman, J. Thiagarajah, 2016, Cellular and molecular gastroenterology and hepatology.

Lubiprostone is non-selective activator of cAMP-gated ion channels and Clc-2 has a minor role in its prosecretory effect in intestinal epithelial cells

J. D. Bois, Parth D. Chhetri, P. Yottasan, 2022 .

Diuresis and reduced urinary osmolality in rats produced by small‐molecule UT‐A‐selective urea transport inhibitors

A. Verkman, C. Esteva‐Font, Marc O. Anderson, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Small-molecule inhibitors of urea transporters.

A. Verkman, Baoxue Yang, Tian-luo Lei, 2014, Sub-cellular biochemistry.

Ocular Surface Ion Transport and Dry Eye Disease

A. Verkman, Neel D. Pasricha, O. Cil, 2022, Current Ophthalmology Reports.

Substituted 4-methylcoumarin inhibitors of SLC26A3 (DRA) for treatment of constipation and hyperoxaluria.

A. Verkman, Marc O Anderson, Onur Cil, 2024, RSC medicinal chemistry.

SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation.

A. Verkman, P. Haggie, Sujin Lee, 2018, JCI insight.

Cystinuria: An Overview of Diagnosis and Medical Management

O. Cil, Sanober Sadiq, Onur Cil, 2022, Turkish archives of pediatrics.

A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats.

A. Verkman, P. Haggie, Marc O. Anderson, 2021, Kidney international.

Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A).

A. Verkman, Marc O. Anderson, L. Ferrera, 2017, Journal of medicinal chemistry.

DRA involvement in linaclotide-stimulated bicarbonate secretion during loss of CFTR function

Shayda M. Abazari, J. Sarthi, A. Trumbull, 2024, JCI insight.

Key role of down-regulated in adenoma (SLC26A3) chloride/bicarbonate exchanger in linaclotide-stimulated intestinal bicarbonate secretion upon loss of CFTR function

C. Kuo, Yanfen Jiang, J. Chan, 2023, bioRxiv.

Inhibition of CFTR‐mediated intestinal chloride secretion as potential therapy for bile acid diarrhea

A. Verkman, M. Donowitz, C. Tse, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Monogenic Causes of Proteinuria in Children

Farzana Perwad, O. Cil, Onur Cil, 2018, Front. Med..

α-Lipoic Acid (ALA) Improves Cystine Solubility in Cystinuria: Report of 2 Cases

Farzana Perwad, O. Cil, Onur Cil, 2020, Pediatrics.