Alan J. Thomas

Alan J. Thomas, J. O'Brien, M. Firbank, 2019, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Cardiac 123I-MIBG planar heart to mediastinum ratios depend on patient size; phantom studies suggest SPECT-CT could improve quantification

Alan J. Thomas, J. O'Brien, J. Lloyd, 2019, Biomedical physics & engineering express.

A comparison of visual and semiquantitative analysis methods for planar cardiac 123I-MIBG scintigraphy in dementia with Lewy bodies

Alan J. Thomas, J. O'Brien, J. Lloyd, 2019, Nuclear medicine communications.

Uniformity of cardiac 123I-MIBG uptake on SPECT images in older adults with normal cognition and patients with dementia

Alan J. Thomas, J. O'Brien, J. Lloyd, 2019, Journal of Nuclear Cardiology.

Revision of assessment toolkits for improving the diagnosis of Lewy body dementia: The DIAMOND Lewy study

Alan J. Thomas, I. McKeith, J. O'Brien, 2018, International journal of geriatric psychiatry.

Depression and cognition in older adults

Alan J. Thomas, J. O'Brien, 2008, Current opinion in psychiatry.

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy

Alan J. Thomas, G. Schellenberg, G. Deuschl, 2022, Movement disorders : official journal of the Movement Disorder Society.

OP-BRAI200337 3763..3775

Alan J. Thomas, J. Mill, K. Morgan, 2021 .

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Timothy A. Miller, Sonja W. Scholz, Jennifer E. Phillips-Cremins, 2020, Neuron.

Smoking, nicotine and dementia.

Alan J. Thomas, Louise Grayson, 2012, Maturitas.

Study of the use of anti-depressants for depression in dementia : the HTA-SADD Trial-a multicentre randomised double-blind , placebo-controlled trial of the clinical effectiveness of sertraline and mirtazapine

Alan J. Thomas, J. Lindesay, G. Livingston, 2011 .

PARIETAL WHITE MATTER LESIONS IN ALZHEIMER’S DISEASE ARE ASSOCIATED WITH CORTICAL NEURODEGENERATIVE PATHOLOGY AND NOT WITH SMALL-VESSEL DISEASE

Alan J. Thomas, C. DeCarli, I. McKeith, 2017, Alzheimer's & Dementia.

Oxford Textbook of Old Age Psychiatry

Alan J. Thomas, T. Dening, R. Jacoby, 2013 .

Cholinergic white matter pathways in dementia with Lewy bodies and Alzheimer’s disease

Nicola J. Ray, Alan J. Thomas, J. O'Brien, 2021, Brain : a journal of neurology.

Coping with dementia in care homes.

Alan J. Thomas, A. Corbett, Kayleigh-Marie Nunez, 2013, Maturitas.

Depression in Older People with Diabetes

Alan J. Thomas, A. Vasudev, 2011 .

Can early phase cardiac [123I]mIBG images be used to diagnose Lewy body disease?

Alan J. Thomas, John-Paul Taylor, M. Firbank, 2022, Nuclear medicine communications.

Slowing on quantitative EEG is associated with transition to dementia in mild cognitive impairment

Alan J. Thomas, John-Paul Taylor, F. Matthews, 2021, International Psychogeriatrics.

Edinburgh Research Explorer Inflammation in Mild Cognitive Impairment due to Parkinson's disease, Lewy Body disease and Alzheimer's disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2019 .

Cytokines and late-life depression.

Alan J. Thomas, Darren Craddock, 2006, Essential psychopharmacology.

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Sonja W. Scholz, Lilah M. Besser, Alan J. Thomas, 2021, Nature Genetics.

DIAGNOSIS OF DEMENTIA IN PARKINSON’S DISEASE IN CLINICAL PRACTICE

Alan J. Thomas, I. McKeith, J. O'Brien, 2017, Alzheimer's & Dementia.

White matter hyperintensities, cortisol levels, brain atrophy and continuing cognitive deficits in late-life depression

Alan J. Thomas, J. O'Brien, R. Barber, 2010, British Journal of Psychiatry.

Computational meta‐analysis of statistical parametric maps in major depression

Osamu Abe, Byung-Joo Ham, Yuqi Cheng, 2016, Human brain mapping.

Quantitative electroencephalography as a marker of cognitive fluctuations in dementia with Lewy bodies and an aid to differential diagnosis

Alan J. Thomas, Fiona E. N. LeBeau, John-Paul Taylor, 2018, Clinical Neurophysiology.

The Dementias Platform UK (DPUK) Data Portal

Ronan A Lyons, Matthew South, Paul M. Matthews, 2019, bioRxiv.

Pharmacotherapy for bipolar disorder in older people

Alan J. Thomas, H. Grunze, A. Vasudev, 2013, Cochrane Database of Systematic Reviews.

Dementia with Lewy bodies: an update and outlook

Alan J. Thomas, I. McKeith, D. Erskine, 2019, Molecular Neurodegeneration.

Neurons from individual early Alzheimer’s disease patients reflect their clinical vulnerability

Alan J. Thomas, D. Ffytche, P. Malhotra, 2021, bioRxiv.

Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment

Alan J. Thomas, T. Hortobágyi, J. O'Brien, 2014, Neurobiology of Aging.

TDP‐43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing

Alan J. Thomas, I. McKeith, D. Erskine, 2017, Brain pathology.

Epigenetic regulation in the pathophysiology of Lewy body dementia

Alan J. Thomas, J. O'Brien, K. Lunnon, 2020, Progress in Neurobiology.

Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes

Nick C Fox, Alan J. Thomas, D. Hernandez, 2021, Biological Psychiatry.

Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease

Alan J. Thomas, C. DeCarli, I. McKeith, 2019, Brain pathology.

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia

Alan J. Thomas, J. O'Brien, R. Akinyemi, 2015, Brain : a journal of neurology.

Sleep in dementia and caregiving – assessment and treatment implications: a review

Alan J. Thomas, David R Lee, 2010, International Psychogeriatrics.

A morphometric examination of neuronal and glial cell pathology in the orbitofrontal cortex in late-life depression

Alan J. Thomas, A. Khundakar, C. Morris, 2010, International Psychogeriatrics.

Utility of the pareidolia test in mild cognitive impairment with Lewy bodies and Alzheimer's disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, International journal of geriatric psychiatry.

Prospective longitudinal evaluation of cytokines in mild cognitive impairment due to AD and Lewy body disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2020, International journal of geriatric psychiatry.

Inflammation in dementia with Lewy bodies

Alan J. Thomas, I. McKeith, D. Erskine, 2022, Neurobiology of Disease.

Dementia with Lewy bodies: an update and outlook

Alan J. Thomas, I. McKeith, D. Erskine, 2019, Molecular Neurodegeneration.

What Can Quantitative Gait Analysis Tell Us about Dementia and Its Subtypes? A Structured Review.

Lynn Rochester, Brook Galna, Alan J. Thomas, 2017, Journal of Alzheimer's disease : JAD.

Increase in interleukin-1 beta in late-life depression

Alan J. Thomas, J. O'Brien, C. Morris, 2005 .

Depression and dementia: cause, consequence or coincidence?

Alan J. Thomas, S. Bennett, 2014, Maturitas.

A systematic review comparing clinical features in early age at onset and late age at onset late-life depression.

Alan J. Thomas, Louise Grayson, 2013, Journal of affective disorders.

Frontotemporal dementia and its subtypes: a genome-wide association study

Alexander Gerhard, Adrian Danek, Luigi Ferrucci, 2014, The Lancet Neurology.

Cell adhesion molecule expression in the dorsolateral prefrontal cortex and anterior cingulate cortex in major depression in the elderly

Alan J. Thomas, I. Ferrier, J. O'Brien, 2002, British Journal of Psychiatry.

Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies

Alan J. Thomas, I. McKeith, A. Khundakar, 2015, Neuropathology and applied neurobiology.

Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology

Alan J. Thomas, Roy W Jones, I. McKeith, 2011, Journal of psychopharmacology.

Functional connectivity in mild cognitive impairment with Lewy bodies

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, Journal of Neurology.

Research criteria for the diagnosis of prodromal dementia with Lewy bodies

Alan J. Thomas, K. Marder, D. Salmon, 2020, Neurology.

Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial

Alan Thomas, Simon Douglas, Clive Ballard, 2005, BMJ : British Medical Journal.

Functional connectivity in dementia with Lewy bodies: A within‐ and between‐network analysis

Andrew M Blamire, Marcus Kaiser, Alan J. Thomas, 2017, Human brain mapping.

Cognitive impairment in depression is not associated with neuropathologic evidence of increased vascular or Alzheimer-type pathology

Alan J. Thomas, J. O'Brien, E. Jaros, 2001, Biological Psychiatry.

Ischemic basis for deep white matter hyperintensities in major depression: a neuropathological study.

Robert Barber, Alan J. Thomas, J. O'Brien, 2002, Archives of general psychiatry.

Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex

Alan J. Thomas, J. Mill, K. Morgan, 2020, bioRxiv.

Clinical usefulness of dopamine transporter SPECT imaging with 123I-FP-CIT in patients with possible dementia with Lewy bodies: randomised study.

Alan J. Thomas, A. Padovani, G. Pizzolato, 2015, The British journal of psychiatry : the journal of mental science.

Genome-wide association findings from the brains for dementia research cohort

Alan J. Thomas, K. Morgan, K. Brookes, 2021, Neurobiology of Aging.

Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology

Alan J. Thomas, J. Mill, S. Love, 2021, Nature Communications.

Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial

Alan J. Thomas, M. Orrell, J. Lindesay, 2011, The Lancet.

Neuropathology of depression in Alzheimer's disease: current knowledge and the potential for new treatments.

Alan J. Thomas, A. Khundakar, 2015, Journal of Alzheimer's disease : JAD.

Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease

Alan J. Thomas, P. Hanson, J. Attems, 2014, Acta Neuropathologica.

Diagnostic accuracy of dopaminergic imaging in prodromal dementia with Lewy bodies

Alan J. Thomas, I. McKeith, J. O'Brien, 2018, Psychological Medicine.

Autopsy validation of 123I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB

Alan J. Thomas, I. McKeith, J. O'Brien, 2017, Neurology.

Systemic Inflammation in Lewy Body Diseases: A Systematic Review

Alan J. Thomas, Eleanor King, 2017, Alzheimer disease and associated disorders.

METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research

Klaus P. Ebmeier, Eric E. Smith, Alan J. Thomas, 2016, Alzheimer's & Dementia.

Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors

Alan J. Thomas, J. O'Brien, M. Firbank, 2011, Brain : a journal of neurology.

Neuropsychological Impairments and Their Cognitive Architecture in Mild Cognitive Impairment (MCI) with Lewy Bodies and MCI-Alzheimer’s Disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, Journal of the International Neuropsychological Society.

Olfactory impairment in mild cognitive impairment with Lewy bodies and Alzheimer's disease.

Alan J. Thomas, John-Paul Taylor, M. Firbank, 2021, International psychogeriatrics.

The Neuropsychological Profile of Mild Cognitive Impairment in Lewy Body Dementias

Alan J. Thomas, P. Gallagher, Bethany Little, 2019, Journal of the International Neuropsychological Society.

Is depression different in older adults

Alan J. Thomas, E. Teper, 2006 .

Depression and vascular disease: what is the relationship?

Alan J. Thomas, J. O'Brien, R. Kalaria, 2004, Journal of affective disorders.

Dynamin1 concentration in the prefrontal cortex is associated with cognitive impairment in Lewy body dementia

Alan J. Thomas, T. Hortobágyi, J. O'Brien, 2014, F1000Research.

Clinical and imaging correlates of amyloid deposition in dementia with Lewy bodies

Alan J. Thomas, J. O'Brien, M. Firbank, 2018, Movement disorders : official journal of the Movement Disorder Society.

A study of orthostatic hypotension in late-life depression.

Alan J. Thomas, J. O'Brien, R. Kenny, 2009, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

DETERMinants of quality of life, care and costs, and consequences of INequalities in people with Dementia and their carers (DETERMIND): A protocol paper

Alan J. Thomas, J. Rusted, C. Brayne, 2019, International journal of geriatric psychiatry.

Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology

Alan J. Thomas, J. Attems, S. Colloby, 2021, Acta Neuropathologica.

Clinical prevalence of Lewy body dementia

Alan J. Thomas, I. McKeith, J. O'Brien, 2018, Alzheimer's Research & Therapy.

Neuropsychiatric symptoms in limbic-predominant age-related TDP-43 encephalopathy and Alzheimer’s disease

Alan J. Thomas, S. Reeves, J. Attems, 2020, Brain : a journal of neurology.

Concomitant LATE‐NC in Alzheimer's disease is not associated with increased tau or amyloid‐β pathological burden

Alan J. Thomas, D. Erskine, J. Attems, 2020, Neuropathology and applied neurobiology.

Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia

Alan J. Thomas, J. Attems, S. Colloby, 2021, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Cognitive Decline in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease: A Prospective Cohort Study.

Alan J. Thomas, I. McKeith, J. O'Brien, 2020, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Relationship between cognition, magnetic resonance white matter hyperintensities, and cardiovascular autonomic changes in late-life depression.

Alan J. Thomas, S. Colloby, M. Firbank, 2012, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Peripheral inflammation in prodromal Alzheimer’s and Lewy body dementias

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2017, Journal of Neurology, Neurosurgery, and Psychiatry.

Genetic variants in glutamate-, Aβ−, and tau-related pathways determine polygenic risk for Alzheimer's disease

Alan J. Thomas, J. Hardy, K. Morgan, 2020, Neurobiology of Aging.

Dynamin 1 concentration in the prefrontal cortex is associated with cognitive impairment in Lewy body dementia

Alan J. Thomas, T. Hortobágyi, J. O'Brien, 2015 .

A prospectively studied clinicopathological case of ‘vascular depression’

Alan J. Thomas, P. English, E. Jaros, 2003, International Journal of Geriatric Psychiatry.

Revisiting DLB Diagnosis

Alan J. Thomas, I. McKeith, John-Paul Taylor, 2016, Journal of geriatric psychiatry and neurology.

Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis.

Alan J. Thomas, I. McKeith, J. O'Brien, 2015, The American journal of psychiatry.

Progression to Dementia in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease

Alan J. Thomas, I. McKeith, J. O'Brien, 2021, Neurology.

Accuracy of dopaminergic imaging as a biomarker for mild cognitive impairment with Lewy bodies

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2020, The British Journal of Psychiatry.

Mild cognitive impairment with Lewy bodies: neuropsychiatric supportive symptoms and cognitive profile

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2020, Psychological Medicine.

Neuropsychiatric symptoms and cognitive profile in mild cognitive impairment with Lewy bodies

Alan J. Thomas, I. McKeith, J. O'Brien, 2018, Psychological Medicine.

Development of assessment toolkits for improving the diagnosis of the Lewy body dementias: feasibility study within the DIAMOND Lewy study

Alan J. Thomas, I. McKeith, J. O'Brien, 2016, International journal of geriatric psychiatry.

Clinical diagnosis of Lewy body dementia

Alan J. Thomas, I. McKeith, J. O'Brien, 2020, BJPsych Open.

In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, NeuroImage: Clinical.

Neuropathological correlates of late-life depression in older people

Alan J. Thomas, R. Stewart, C. Brayne, 2011, British Journal of Psychiatry.

Functional connectivity in late-life depression using resting-state functional magnetic resonance imaging.

Andrew M Blamire, Alan J. Thomas, J. O'Brien, 2010, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias.

Alan J. Thomas, A. Khundakar, L. Allan, 2014, Brain : a journal of neurology.

Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial

Nick C Fox, Alan J. Thomas, N. J. Thai, 2021, The Lancet Neurology.

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.

Nick C Fox, Alan J. Thomas, D. Hernandez, 2018, Nature Medicine.

Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer’s disease

Imre Lengyel, Lynn Rochester, Iracema Leroi, 2019, BMJ Open.

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

Nick C Fox, Alan J. Thomas, D. Hernandez, 2018, Brain : a journal of neurology.

Increase in interleukin-1beta in late-life depression.

Alan J. Thomas, J. O'Brien, C. Morris, 2005, The American journal of psychiatry.

Morphometric analysis of neuronal and glial cell pathology in the caudate nucleus in late-life depression.

Alan J. Thomas, A. Khundakar, C. Morris, 2011, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

A neuropathological study of periventricular white matter hyperintensities in major depression.

Robert Barber, Alan J. Thomas, Robert Perry, 2003, Journal of affective disorders.

Decreased Levels of VAMP2 and Monomeric Alpha-Synuclein Correlate with Duration of Dementia.

Alan J. Thomas, T. Hortobágyi, J. O'Brien, 2015, Journal of Alzheimer's disease : JAD.

Balance Impairments as Differential Markers of Dementia Disease Subtype

Alan J. Thomas, B. Galna, L. Rochester, 2021, Frontiers in Bioengineering and Biotechnology.

Cellular morphometry in late-life depression: a review of postmortem studies.

Alan J. Thomas, A. Khundakar, 2014, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

BOLD activation of the ventromedial prefrontal cortex in patients with late life depression and comparison participants

Alan J. Thomas, J. Gati, M. Firbank, 2017, International Psychogeriatrics.

Neurodegenerative brain changes are associated with area deprivation in the United Kingdom: findings from the Brains for Dementia Research study

Alan J. Thomas, D. Erskine, J. Attems, 2021, Acta neuropathologica communications.

Mild Cognitive Impairment: the Manchester consensus

Nick C Fox, Alan J. Thomas, J. O'Brien, 2020, Age and ageing.

Neuropathological Changes in Dementia With Lewy Bodies and the Cingulate Island Sign

Alan J. Thomas, J. Attems, C. Morris, 2019, Journal of neuropathology and experimental neurology.

Revisiting DLB Diagnosis: A Consideration of Prodromal DLB and of the Diagnostic Overlap With Alzheimer Disease

Alan J. Thomas, I. McKeith, John-Paul Taylor, 2018 .

The dementia cognitive fluctuation scale, a new psychometric test for clinicians to identify cognitive fluctuations in people with dementia.

Alan J. Thomas, I. McKeith, U. Mosimann, 2014, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Visual complaints and visual hallucinations in Parkinson's disease.

Alan J. Thomas, T. Nef, I. McKeith, 2014, Parkinsonism & related disorders.

Mild cognitive impairment with Lewy bodies: blood perfusion with arterial spin labelling

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2020, Journal of Neurology.

Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies.

Alan J. Thomas, John-Paul Taylor, I. McKeith, 2017, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Functional connectivity of the nucleus basalis of Meynert in Lewy body dementia and Alzheimer’s disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, International Psychogeriatrics.

The segregated connectome of late-life depression: a combined cortical thickness and structural covariance analysis

John T. O'Brien, Elijah Mak, Alan Thomas, 2016, Neurobiology of Aging.

White matter changes in late-life depression: a diffusion tensor imaging study.

Alan J. Thomas, J. O'Brien, S. Colloby, 2011, Journal of affective disorders.

Morphometric analysis of neuronal and glial cell pathology in the dorsolateral prefrontal cortex in late-life depression

Alan J. Thomas, A. Khundakar, C. Morris, 2009, British Journal of Psychiatry.

A 3-month, randomized, placebo-controlled, neuroleptic discontinuation study in 100 people with dementia: the neuropsychiatric inventory median cutoff is a predictor of clinical outcome.

Alan J. Thomas, J. O'Brien, A. Swann, 2004, The Journal of clinical psychiatry.

Microbleeds in dementia with Lewy bodies

Alan J. Thomas, J. O'Brien, M. Firbank, 2020, Journal of Neurology.

Electrophysiological changes in late life depression and their relation to structural brain changes

Alan J. Thomas, J. O'Brien, S. Köhler, 2010, International Psychogeriatrics.

Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein

Alan J. Thomas, Fiona E. N. LeBeau, John-Paul Taylor, 2020, Frontiers in Neuroscience.

Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies

Alan J. Thomas, I. McKeith, D. Collerton, 2019, Neuroscience Bulletin.

Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders

Alan J. Thomas, J. Attems, C. Morris, 2019, Brain pathology.

Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial

Alan J. Thomas, G. Livingston, Sube Banerjee, 2021, The Lancet.

Feasibility of a staff training and support programme to improve pain assessment and management in people with dementia living in care homes

Alan J. Thomas, T. Dening, C. Ballard, 2018, International journal of geriatric psychiatry.

The landscape of pain management in people with dementia living in care homes: a mixed methods study

Alan J. Thomas, A. Corbett, S. Closs, 2016, International journal of geriatric psychiatry.

Structural correlates of attention dysfunction in Lewy body dementia and Alzheimer’s disease: an ex-Gaussian analysis

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2019, Journal of Neurology.

Structural Brain Correlates of Attention Dysfunction in Lewy Body Dementias and Alzheimer’s Disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2018, Front. Aging Neurosci..

Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial

Alan J. Thomas, J. Lindesay, J. O'Brien, 2013, British Journal of Psychiatry.

Peripheral inflammation in mild cognitive impairment with possible and probable Lewy body disease and Alzheimer’s disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2019, International Psychogeriatrics.

Regional cerebral blood flow in late-life depression: arterial spin labelling magnetic resonance study

Alan J. Thomas, J. O'Brien, S. Colloby, 2012, British Journal of Psychiatry.

Clinicians' ability to diagnose dementia with Lewy bodies is not affected by β-amyloid load

Alan J. Thomas, I. McKeith, D. Lett, 2015, Neurology.

Assessment of cognitive fluctuation in dementia: a systematic review of the literature

Alan J. Thomas, John-Paul Taylor, David R Lee, 2012, International journal of geriatric psychiatry.

Blood mRNA Expression in Alzheimer's Disease and Dementia With Lewy Bodies.

Alan J. Thomas, D. Erskine, S. Cockell, 2022, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Improving the identification of dementia with Lewy bodies in the context of an Alzheimer’s-type dementia

Alan J. Thomas, D. Lett, John-Paul Taylor, 2018, Alzheimer's Research & Therapy.

Imaging in prodromal dementia with Lewy bodies: Where do we stand?

Alan J. Thomas, John-Paul Taylor, P. Donaghy, 2019, International journal of geriatric psychiatry.

123I-FP-CIT striatal binding ratios do not decrease significantly with age in older adults

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2019, Annals of Nuclear Medicine.

Dysfunctional brain dynamics and their origin in Lewy body dementia

Andrew M Blamire, Marcus Kaiser, Alan J. Thomas, 2019, Brain : a journal of neurology.

The Role of EEG in the Diagnosis, Prognosis and Clinical Correlations of Dementia with Lewy Bodies—A Systematic Review

Alan J. Thomas, Fiona E. N. LeBeau, John-Paul Taylor, 2020, Diagnostics.

Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression.

Alan J. Thomas, I. Ferrier, J. O'Brien, 2004, The American journal of psychiatry.

What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia

Alan J. Thomas, I. McKeith, T. Minett, 2003, International journal of geriatric psychiatry.

The revised Addenbrooke's Cognitive Examination can facilitate differentiation of dementia with Lewy bodies from Alzheimer's disease

Alan J. Thomas, J. O'Brien, J. Rowe, 2020, International journal of geriatric psychiatry.

Evolution of clinical features in possible DLB depending on FP-CIT SPECT result

Alan J. Thomas, D. Aarsland, A. Padovani, 2016, Neurology.

Mild cognitive impairment: safe to drive?

Alan J. Thomas, John-Paul Taylor, K. Olsen, 2014, Maturitas.

Accuracy of Cardiac Innervation Scintigraphy for Mild Cognitive Impairment With Lewy Bodies

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, Neurology.

Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT

Alan J. Thomas, I. McKeith, John-Paul Taylor, 2021, Programme Grants for Applied Research.

The challenges of COVID‐19 for people with dementia with Lewy bodies and family caregivers

Alan J. Thomas, I. McKeith, J. O'Brien, 2020, International journal of geriatric psychiatry.

Symptoms associated with Lewy body disease in mild cognitive impairment

Alan J. Thomas, I. McKeith, J. O'Brien, 2017, International journal of geriatric psychiatry.

Inflammation in mild cognitive impairment due to Parkinson's disease, Lewy body disease, and Alzheimer's disease

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2019, International journal of geriatric psychiatry.

Progression of Clinical Features in Lewy Body Dementia Can Be Detected Over 6 Months

Alan J. Thomas, I. McKeith, J. O'Brien, 2021, Neurology.

Diffusion imaging in dementia with Lewy bodies: Associations with amyloid burden, atrophy, vascular factors and clinical features.

Alan J. Thomas, J. O'Brien, M. Firbank, 2020, Parkinsonism & related disorders.

A comparison of the efficacy of donepezil in Parkinson's disease with Dementia and Dementia with Lewy bodies

Alan J. Thomas, I. McKeith, D. Burn, 2005, International journal of geriatric psychiatry.

Introduction of a Management Toolkit for Lewy Body Dementia: A Pilot Cluster‐Randomized Trial

Alan J. Thomas, I. McKeith, J. O'Brien, 2020, Movement disorders : official journal of the Movement Disorder Society.

Clinical symptoms in mild cognitive impairment with Lewy bodies: Frequency, time of onset, and discriminant ability

Alan J. Thomas, I. McKeith, John-Paul Taylor, 2023, European journal of neurology.

A double-blind randomized placebo-controlled withdrawal trial comparing memantine and antipsychotics for the long-term treatment of function and neuropsychiatric symptoms in people with Alzheimer's disease (MAIN-AD).

Alan J. Thomas, D. Aarsland, A. Burns, 2015, Journal of the American Medical Directors Association.

Hippocampal and insula volume in mild cognitive impairment with Lewy bodies.

Alan J. Thomas, J. O'Brien, John-Paul Taylor, 2021, Parkinsonism & related disorders.

Genome-wide association study of autopsy-confirmed Multiple System Atrophy identifies common variants near ZIC1 and ZIC4

Alan J. Thomas, A. Peters, G. Schellenberg, 2021, medRxiv.

Dementia with Lewy Bodies and Parkinson’s Disease Dementia Show No differences in Resting State Functional MRI

Alan J. Thomas, I. McKeith, J. O'Brien, 2015 .

Author response: Autopsy validation of 123I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB

Alan J. Thomas, I. McKeith, J. O'Brien, 2017, Neurology.

Aβ42/Aβ40 and Aβ42/Aβ38 Ratios Are Associated with Measures of Gait Variability and Activities of Daily Living in Mild Alzheimer’s Disease: A Pilot Study

Alan J. Thomas, B. Galna, P. Malhotra, 2018, Journal of Alzheimer's disease : JAD.

Cellular pathology within the anterior cingulate cortex of patients with late-life depression: A morphometric study

Alan J. Thomas, A. Khundakar, C. Morris, 2011, Psychiatry Research: Neuroimaging.

Cognitive style and depressive symptoms in elderly people - extending the empirical evidence for the cognitive vulnerability-stress hypothesis.

Alan J. Thomas, D. Collerton, T. Meyer, 2010, Behaviour research and therapy.

Morphometric changes in early- and late-life major depressive disorder: evidence from postmortem studies

Alan J. Thomas, A. Khundakar, 2009, International Psychogeriatrics.

Prevalence and severity of symptoms suggestive of gastroparesis in prodromal dementia with Lewy bodies

Alan J. Thomas, I. McKeith, J. O'Brien, 2019, International journal of geriatric psychiatry.

Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias.

Alan J. Thomas, A. Khundakar, V. Deramecourt, 2014, Journal of neuropathology and experimental neurology.

Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia

Alan J. Thomas, T. Hortobágyi, J. O'Brien, 2017, Journal of Alzheimer's disease : JAD.

Is depression really different in older people?

Alan J. Thomas, 2013, International Psychogeriatrics.

Criteria are needed for research in vascular depression

Alan J. Thomas, 2004, International Psychogeriatrics.

'Bipolar disorder' in the elderly: what's in a name?

Alan J. Thomas, A. Vasudev, 2010, Maturitas.

Long-term incidence of depression and predictors of depressive symptoms in older stroke survivors

Alan J. Thomas, J. O'Brien, L. Allan, 2013, British Journal of Psychiatry.

Soluble cell adhesion molecules in late-life depression

Alan J. Thomas, J. O'Brien, C. Morris, 2007, International Psychogeriatrics.

Neuropsychiatric Co-Morbidity in Dementia With and Without Movement Disorders

Alan J. Thomas, C. Ballard, 2003 .

A study of orthostatic hypotension, heart rate variability and baroreflex sensitivity in late-life depression.

Alan J. Thomas, J. O'Brien, M. Tan, 2011, Journal of affective disorders.

Evaluation of daily walking activity and gait profiles: a novel application of a time series analysis framework

Silvia Del Din, Christopher Buckley, Brook Galna, 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

Depression and Anxiety: Admission and Discharge

Alan J. Thomas, 2016 .

The Possible Applications (And Pitfalls!) Of Stereological Analysis In Postmortem Brain Research

Alan J. Thomas, A. Khundakar, 2013 .

Relationship of orthostatic blood pressure to white matter hyperintensities and subcortical volumes in late-life depression

Alan J. Thomas, J. O'Brien, S. Colloby, 2011, British Journal of Psychiatry.

Translating progress in neuroimaging into clinical practice

Alan J. Thomas, R. Durcan, 2018, International Psychogeriatrics.

The Dementias Platform UK (DPUK) Data Portal

Alan J. Thomas, J. Gallacher, P. Matthews, 2019, bioRxiv.

Pathological Changes to the Subcortical Visual System and its Relationship to Visual Hallucinations in Dementia with Lewy Bodies

Alan J. Thomas, I. McKeith, D. Collerton, 2019, Neuroscience Bulletin.