Maik Pietzner

发表

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes

Christoph Bock, Maik Pietzner, Albert Koulman, 2020, bioRxiv.

Extreme phenotypes define epigenetic and metabolic signatures in cardiometabolic syndrome.

Paul D. W. Kirk, Matthew C. Sims, K. Downes, 2020 .

A Neanderthal OAS1 isoform Protects Against COVID-19 Susceptibility and Severity: Results from Mendelian Randomization and Case-Control Studies

C. Greenwood, J. Richards, V. Mooser, 2020 .

ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19

C. Conrad, F. Heppner, N. Wareham, 2022, Nature Communications.

The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals

Benjamin S. Glicksberg, Chen-Yang Su, Gyu Ho Lee, 2022, Clinical Proteomics.

Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations

J. Danesh, M. Schulze, E. Riboli, 2020, Diabetes care.

Systemic proteome adaptions to 7-day complete caloric restriction in humans

C. Langenberg, Ø. Skattebo, P. Jeppesen, 2024, Nature metabolism.

Plasma Metabolomics to Identify and Stratify Patients with Impaired Glucose Tolerance.

W. Rathmann, H. Völzke, N. Friedrich, 2019, The Journal of clinical endocrinology and metabolism.

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

C. Greenwood, J. Richards, V. Mooser, 2021, Nature Medicine.

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

M. P. Concas, S. Bandinelli, C. Gieger, 2024, Nature communications.

Integrating Genetics and the Plasma Proteome to Predict the Risk of Type 2 Diabetes

C. Langenberg, M. Pietzner, Julia Carrasco Zanini, 2020, Current Diabetes Reports.

A cross-platform approach identifies genetic regulators of human metabolism and health

J. Danesh, A. Wood, V. Zuber, 2021, Nature Genetics.

Synergistic insights into human health from aptamer- and antibody-based proteomic profiling

A. Hingorani, N. Wareham, J. Luan, 2021, Nature Communications.

Multi-omic prediction of incident type 2 diabetes

C. Langenberg, E. Wheeler, N. Kerrison, 2023, Diabetologia.

Proteomic signatures for identification of impaired glucose tolerance

Matthew J. Westacott, N. Wareham, C. Langenberg, 2022, Nature Medicine.

Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19

Grant D. Huang, Yan V. Sun, J. Danesh, 2020, Nature Medicine.

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region

Christopher N. Foley, N. Wareham, C. Langenberg, 2021, Diabetes.

Identi ﬁ cation of circulating proteins associated with general cognitive function among middle-aged and older adults

V. Emilsson, C. Sitlani, A. Beiser, 2022 .

Complex patterns of multimorbidity associated with severe COVID-19 and long COVID

G. Kastenmüller, M. Arnold, T. Nakanishi, 2024, Communications medicine.

A predictive atlas of disease onset from retinal fundus photographs

Lukas Loock, S. Künzel, J. Steinfeldt, 2024, medRxiv.

ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon

M. Caulfield, E. Gamazon, M. Pirmohamed, 2023, Nature communications.

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure

María P. Magariños, Steffen E. Petersen, P. Munroe, 2023, Nature communications.

Proteogenomic links to human metabolic diseases

N. Wareham, C. Langenberg, E. Wheeler, 2023, Nature Metabolism.

Rare and common genetic determinants of metabolic individuality and their effects on human health

Spiros C. Denaxas, J. Danesh, T. Spector, 2022, Nature Medicine.

Detection and characterization of male sex chromosome abnormalities in the UK Biobank study.

Samuel E. Jones, J. Tyrrell, T. Frayling, 2022, Genetics in medicine : official journal of the American College of Medical Genetics.

GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health

Po-Ru Loh, N. Wareham, K. Ong, 2021, Nature Communications.

Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases

C. Gieger, F. Kronenberg, E. Boerwinkle, 2022, JCI insight.

Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases

C. Gieger, F. Kronenberg, E. Boerwinkle, 2022 .

Metabolic signature associated with parameters of the complete blood count in apparently healthy individuals

H. Völzke, M. Nauck, J. Adamski, 2019, Journal of cellular and molecular medicine.

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

J. Danesh, A. Wood, V. Zuber, 2020, bioRxiv.

Insights into genetic variants associated with NASH-fibrosis from metabolite profiling

E. Fauman, N. Wareham, M. Allison, 2020, Human molecular genetics.

Urine Metabolomics by 1H-NMR Spectroscopy Indicates Associations between Serum 3,5-T2 Concentrations and Intermediary Metabolism in Euthyroid Humans

H. Völzke, G. Homuth, U. Völker, 2015, European Thyroid Journal.

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

Ronan M. T. Fleming, R. Fleming, R. Krüger, 2019, Cell reports.

Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health

A. Mörseburg, K. Kentistou, D. Rimmington, 2024, Nature metabolism.

Damaging mutations in Liver X Receptor-alpha (LXRa) are hepatotoxic and implicate cholesterol sensing in liver health

A. Mörseburg, K. Kentistou, D. Rimmington, 2022 .