David V. Schaffer

发表

Figure 3, Sequential soluble factors specify differentiation programs.

Shawdee Eshghi, David V. Schaffer, 2008 .

HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency

Adam P. Arkin, David V. Schaffer, Ron Skupsky, 2010, PLoS Comput. Biol..

Genetic Approaches to Tissue Engineering

Savio L. C. Woo, David V. Schaffer, Jeffrey Bonadio, 2002 .

Genetic Selection for Context-Dependent Stochastic Phenotypes: Sp1 and TATA Mutations Increase Phenotypic Noise in HIV-1 Gene Expression

Adam P. Arkin, David V. Schaffer, Ron Skupsky, 2013, PLoS Comput. Biol..

Protocol to Fabricate Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics

Nicole A. Repina, David V. Schaffer, Ravi S. Kane, 2020, STAR protocols.

Molecular Engineering of Stem Cell and Gene Therapies

David V. Schaffer, 2009 .

Figure 1, Schematic overview view of niche components.

Shawdee Eshghi, David V. Schaffer, 2008 .

Computational Models of the Notch Network Elucidate Mechanisms of Context-dependent Signaling

Smita Agrawal, David V. Schaffer, Colin Archer, 2009, PLoS Comput. Biol..

The delivery challenge: fulfilling the promise of therapeutic genome editing

David V. Schaffer, Jie Li, Joost van Haasteren, 2020, Nature Biotechnology.

Computational Models of HIV-1 Resistance to Gene Therapy Elucidate Therapy Design Principles

Adam P. Arkin, Sharon Aviran, David V. Schaffer, 2010, PLoS Comput. Biol..

Single-cell western blotting

Amy E. Herr, David V. Schaffer, Alex J. Hughes, 2014, Nature Methods.

Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics

Nicole A. Repina, David V. Schaffer, Ravi S. Kane, 2019, bioRxiv.

119. Engineering a Self-Inactivating CRISPR System for AAV Vectors

David V. Schaffer, Benjamin E. Epstein, 2016 .

eScholarship Title Supplemental Data : Stochastic Gene Expression in a Lentiviral Positive Feedback Loop : HIV-1 Tat Fluctuations Drive Phenotypic Diversity Permalink

Adam P. Arkin, Leor S. Weinberger, Jared E. Toettcher, 2005 .

Expansion of human pluripotent stem cells

David V. Schaffer, D. Schaffer, Maroof M. Adil, 2017 .

Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: A model system to study neurotoxicity in Alzheimer's disease

Mu-ming Poo, Teresa Head-Gordon, David V. Schaffer, 2014, Neurobiology of Disease.

Engineering Biomaterials for Synthetic Neural Stem Cell Microenvironments

Kevin E. Healy, David V. Schaffer, D. Schaffer, 2008 .

Antiviral RNAi: Translating Science Towards Therapeutic Success

David V. Schaffer, Priya S. Shah, D. Schaffer, 2011, Pharmaceutical Research.

Development of a Low Bias Method for Characterizing Viral Populations Using Next Generation Sequencing Technology

Lior Pachter, Adam P. Arkin, Stephanie M. Willerth, 2010, PloS one.

High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform

Jonathan S. Dordick, David V. Schaffer, Douglas S. Clark, 2016, Stem cell reports.

Colloids as Mobile Substrates for the Implantation and Integration of Differentiated Neurons into the Mammalian Brain

Jae-Hyung Jang, Sophie Pautot, David V. Schaffer, 2012, PloS one.

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

Fred H. Gage, Brian K. Kaspar, David V. Schaffer, 2003, Nature Neuroscience.

Gene therapy and gene delivery systems

David V. Schaffer, Weichang Zhou, D. Schaffer, 2005 .

Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery

Jennifer A. Doudna, David V. Schaffer, Thomas Gaj, 2017, Nucleic acids research.

Engineering adeno-associated viruses for clinical gene therapy

David V. Schaffer, D. Schaffer, M. Kotterman, 2014, Nature Reviews Genetics.

Biogenic Gas Nanostructures as Ultrasonic Molecular Reporters

F. Stuart Foster, Arkosnato Neogy, Melissa Yin, 2014, Nature nanotechnology.

Designer Gene Delivery Vectors: Molecular Engineering and Evolution of Adeno-Associated Viral Vectors for Enhanced Gene Transfer

David V. Schaffer, D. Schaffer, Inchan Kwon, 2007, Pharmaceutical Research.

Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants

Adam P. Arkin, David V. Schaffer, John C. Burnett, 2010, Journal of Virology.

CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington’s Disease Mouse Model

David V. Schaffer, Thomas Gaj, D. Schaffer, 2019, Molecular therapy. Nucleic acids.

Network News: Innovations in 21st Century Systems Biology

Adam P. Arkin, David V. Schaffer, A. Arkin, 2011, Cell.

A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

John G. Flannery, Deniz Dalkara, David V. Schaffer, 2009, PloS one.

Computational Design of Antiviral RNA Interference Strategies That Resist Human Immunodeficiency Virus Escape

Joshua N. Leonard, David V. Schaffer, D. Schaffer, 2005, Journal of Virology.

Mastering their own fates through the matrix

David V. Schaffer, Sanjay Kumar, Eric L. Qiao, 2019, Nature Materials.

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

John E. Dueber, David V. Schaffer, D. Schaffer, 2018, Nature.

A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation

David V. Schaffer, Yuguo Lei, D. Schaffer, 2013, Proceedings of the National Academy of Sciences.

Theoretical Design of a Gene Therapy To Prevent AIDS but Not Human Immunodeficiency Virus Type 1 Infection

Adam P. Arkin, Leor S. Weinberger, David V. Schaffer, 2003, Journal of Virology.