Søren L Pedersen

发表

Automated ‘X‐Y’ robot for peptide synthesis with microwave heating: application to difficult peptide sequences and protein domains

Leila Malik, A Pernille Tofteng, Søren L Pedersen, 2010, Journal of peptide science : an official publication of the European Peptide Society.

Instruments for automated peptide synthesis.

Søren L Pedersen, Knud J Jensen, K. Jensen, 2013, Methods in molecular biology.

Microwave heating in solid-phase peptide synthesis.

Søren L Pedersen, A. P. Tofteng, Leila Malik, 2012, Chemical Society reviews.

Modifying the conserved C‐terminal tyrosine of the peptide hormone PYY3‐36 to improve Y2 receptor selectivity

Søren L Pedersen, B. Holst, N. Vrang, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Half‐Life Extension of Biopharmaceuticals using Chemical Methods: Alternatives to PEGylation

Søren L Pedersen, Knud J Jensen, K. Jensen, 2016, ChemMedChem.

Peptide Architecture: Adding an α‐Helix to the PYY Lysine Side Chain Provides Nanomolar Binding and Body‐Weight‐Lowering Effects

Søren L Pedersen, N. Vrang, K. Jensen, 2010, ChemMedChem.

Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control

Søren L Pedersen, P. J. Larsen, P. Vilmann, 2018, Peptides.

Peptide hormone isoforms: N‐terminally branched PYY3–36 isoforms give improved lipid and fat‐cell metabolism in diet‐induced obese mice

Søren L Pedersen, B. Holst, N. Vrang, 2010, Journal of peptide science : an official publication of the European Peptide Society.

Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases.

Søren L Pedersen, N. Hatzakis, L. Iversen, 2015, Nature chemical biology.

Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy.

Søren L Pedersen, J. Jelsing, N. Vrang, 2017, Molecular pharmaceutics.

GUB06‐046, a novel secretin/glucagon‐like peptide 1 co‐agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice

Søren L Pedersen, J. Jelsing, N. Vrang, 2017, Journal of peptide science : an official publication of the European Peptide Society.

Novel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice

Søren L Pedersen, J. Jelsing, N. Vrang, 2018, Physiology & Behavior.

Adrenomedullin and glucagon-like peptide-1 have additive effects on food intake in mice.

Søren L Pedersen, J. Jelsing, L. Rudkjær, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization.

Søren L Pedersen, N. Hatzakis, S. Nielsen, 2019, Molecular pharmaceutics.

Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues.

Søren L Pedersen, J. Jelsing, N. Vrang, 2017, Journal of medicinal chemistry.

Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect

Søren L Pedersen, J. Jelsing, N. Vrang, 2022, Scientific Reports.

Microwave Heating in the Solid‐Phase Synthesis of N‐Methylated Peptides: When Is Room Temperature Better?

Søren L Pedersen, Renée Roodbeen, K. Jensen, 2012 .

Peptide Synthesis and Applications

Søren L Pedersen, K. Jensen, Pernille Tofteng Shelton, 2013, Methods in Molecular Biology.

Peptide release, side-chain deprotection, work-up, and isolation.

Søren L Pedersen, K. Jensen, 2013, Methods in molecular biology.

Effect of residual water and microwave heating on the half-life of the reagents and reactive intermediates in peptide synthesis.

Søren L Pedersen, D. Staerk, A. P. Tofteng, 2012, Chemistry.

Membrane Curvature Sensing by Amphipathic Helices

Søren L Pedersen, J. E. Rasmussen, M. B. Jensen, 2011, The Journal of Biological Chemistry.

Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment.

Søren L Pedersen, N. Hatzakis, D. Stamou, 2017, Biophysical journal.

Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells.

Søren L Pedersen, A. Callan-Jones, L. Oddershede, 2017, Nature chemical biology.

Semi‐automated microwave‐assisted SPPS: Optimization of protocols and synthesis of difficult sequences

Søren L Pedersen, K. Jensen, K. K. Sørensen, 2010, Biopolymers.

Neuromedin U inhibits food intake partly by inhibiting gastric emptying

Søren L Pedersen, J. Jelsing, B. Holst, 2015, Peptides.

Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its Alternatives.

Søren L Pedersen, K. Jensen, Esben M. Bech, 2018, ACS medicinal chemistry letters.

Synthesis and evaluation of novel lipidated neuromedin U analogs with increased stability and effects on food intake

Søren L Pedersen, J. E. Rasmussen, J. Jelsing, 2015, Journal of peptide science : an official publication of the European Peptide Society.

How Membrane Geometry Regulates Protein Sorting Independently of Mean Curvature

Søren L Pedersen, N. Hatzakis, K. Weninger, 2020, ACS central science.

Improving membrane binding as a design strategy for amphipathic peptide hormones: 2‐helix variants of PYY3‐36

Søren L Pedersen, B. Holst, N. Vrang, 2012, Journal of peptide science : an official publication of the European Peptide Society.

Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling

Søren L Pedersen, N. Vrang, K. Strømgaard, 2023, Peptides.