Berthold Göttgens

发表

BloodExpress: a database of gene expression in mouse haematopoiesis

Subhajyoti De, Diego Miranda-Saavedra, Matthew W. Trotter, 2008, Nucleic Acids Res..

Modeling Reveals Bistability and Low-Pass Filtering in the Network Module Determining Blood Stem Cell Fate

Berthold Göttgens, Jatin Narula, Aileen M. Smith, 2010, PLoS Comput. Biol..

TFBScluster web server for the identification of mammalian composite regulatory elements

Berthold Göttgens, Ian John Donaldson, B. Göttgens, 2006, Nucleic Acids Res..

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

Fabian J. Theis, Berthold Göttgens, Fabian J Theis, 2017, Genome Biology.

CODEX: a next-generation sequencing experiment database for the haematopoietic and embryonic stem cell communities

Patrick Lombard, Berthold Göttgens, Adam C. Wilkinson, 2014, Nucleic Acids Res..

Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data

Berthold Göttgens, Boris Adryan, Daphne Ezer, 2016, PLoS Comput. Biol..

Probabilistic PCA of censored data: accounting for uncertainties in the visualization of high-throughput single-cell qPCR data

Fabian J. Theis, Berthold Göttgens, Florian Buettner, 2014, Bioinform..

SCNS: a graphical tool for reconstructing executable regulatory networks from single-cell genomic data

Berthold Göttgens, Nir Piterman, Jasmin Fisher, 2018, BMC Systems Biology.

BTR: training asynchronous Boolean models using single-cell expression data

Berthold Göttgens, Nir Piterman, Jasmin Fisher, 2016, BMC Bioinformatics.

TFBScluster: a resource for the characterization of transcriptional regulatory networks

Berthold Göttgens, Michael Chapman, Ian John Donaldson, 2005, Bioinform..

A single-cell molecular map of mouse gastrulation and early organogenesis

Berthold Göttgens, John C. Marioni, Richard C. V. Tyser, 2019, Nature.

TRES predicts transcription control in embryonic stem cells

Anagha Joshi, Patrick Lombard, Berthold Göttgens, 2014, Bioinform..

Fast and sensitive multiple alignment of large genomic sequences

Michael Brudno, Berthold Göttgens, Burkhard Morgenstern, 2003, BMC Bioinformatics.

A graphical model approach visualizes regulatory relationships between genome-wide transcription factor binding profiles

Berthold Göttgens, Lorenz Wernisch, David Ruau, 2016, Briefings Bioinform..

Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development.

Berthold Göttgens, Noel Buckley, Anthony R Green, 2004, Human molecular genetics.

Analysis of multiple genomic sequence alignments: a web resource, online tools, and lessons learned from analysis of mammalian SCL loci.

Berthold Göttgens, Jane Rogers, Anthony R Green, 2004, Genome research.

Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits

Berthold Göttgens, Nicole Soranzo, Suthesh Sivapalaratnam, 2011, PLoS genetics.

Reconstructing blood stem cell regulatory network models from single-cell molecular profiles

Berthold Göttgens, David G Kent, F. Hamey, 2017, Proceedings of the National Academy of Sciences.

Characterisation of transcriptional networks in blood stem and progenitor cells using high-throughput single cell gene expression analysis

Fabian J. Theis, Anagha Joshi, Berthold Göttgens, 2013, Nature Cell Biology.

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

Berthold Göttgens, B. Göttgens, M. Bycroft, 2010, Nature Structural &Molecular Biology.

Preview: Published ahead of advance online publication Processing, visualising and reconstructing network models from single cell data

Berthold Göttgens, Jasmin Fisher, Victoria Moignard, 2015 .

Analysis of vertebrate SCL loci identifies conserved enhancers

Berthold Göttgens, Sabine Bahn, D. Grafham, 2000, Nature Biotechnology.

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor

Berthold Göttgens, Isabel Hidalgo, David Bryder, 2017, Cell reports.

CoMoDis: composite motif discovery in mammalian genomes

Berthold Göttgens, B. Göttgens, I. Donaldson, 2006, Nucleic acids research.

Reconstructing blood stem cell regulatory network models from single-cell molecular profiles

Berthold Göttgens, David G. Kent, Fiona K. Hamey, 2017 .

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis

Jens Lichtenberg, Berthold Göttgens, Feng Yue, 2019, bioRxiv.

Dissecting stem cell differentiation using single cell expression profiling.

Berthold Göttgens, Victoria Moignard, B. Göttgens, 2016, Current opinion in cell biology.

Advancing haematopoietic stem and progenitor cell biology through single‐cell profiling

Berthold Göttgens, Nicola K. Wilson, F. Hamey, 2016, FEBS letters.

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes.

Berthold Göttgens, Michael I Sadowski, B. Göttgens, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium

Berthold Göttgens, Adam C. Wilkinson, Benjamin D. Simons, 2015, Cell reports.

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.

Gos Micklem, Berthold Göttgens, George S Vassiliou, 2012, Blood.

Building an ENCODE-style data compendium on a shoestring

Berthold Göttgens, Rebecca Hannah, David Ruau, 2013, Nature Methods.

Deciphering transcriptional control mechanisms in hematopoiesis:the impact of high-throughput sequencing technologies.

Berthold Göttgens, Nicola K. Wilson, Marloes R. Tijssen, 2011, Experimental hematology.

A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms.

Anagha Joshi, Berthold Göttgens, Rebecca Hannah, 2011, Experimental hematology.

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

Anagha Joshi, Berthold Göttgens, Rebecca Hannah, 2012, Cell stem cell.

A Single Cell Haematopoietic Landscape Resolves Eight Lineage Trajectories and Defects in Kit Mutant Mice

Fabian J. Theis, Berthold Göttgens, Fabian J Theis, 2018, Experimental Hematology.

Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine

Berthold Göttgens, Frank Reimann, Wajid Jawaid, 2017, Molecular metabolism.

Erratum: DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias (Cancer Cell (2016) 29(6) (922–934) (S1535610816302082) (10.1016/j.ccell.2016.05.003))

Berthold Göttgens, David Ruau, Xueqiu Lin, 2016 .

Transcriptional network control of normal and leukaemic haematopoiesis

Berthold Göttgens, B. Göttgens, J. Sive, 2014, Experimental cell research.

The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.

Mark A. Dawson, Diego Miranda-Saavedra, Sarah A. Teichmann, 2009, Blood.

Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions.

Berthold Göttgens, Joshua M. Stuart, Daniel E. Carlin, 2015, Cell stem cell.

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Fabian J. Theis, Berthold Göttgens, Chris P. Ponting, 2015, Cell stem cell.

Function-based Identification of Mammalian Enhancers Using Site-Specific Integration

Berthold Göttgens, Axel Visel, Len A Pennacchio, 2014, Nature Methods.

Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors

Berthold Göttgens, Elisa Laurenti, Evangelia Diamanti, 2018, Nature Communications.

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

Berthold Göttgens, John E. Pimanda, Nicola K. Wilson, 2007, Proceedings of the National Academy of Sciences.

Maximum parsimony analysis of gene expression profiles permits the reconstruction of developmental cell lineage trees.

Anagha Joshi, Berthold Göttgens, B. Göttgens, 2011, Developmental biology.

The Epidermis Comprises Autonomous Compartments Maintained by Distinct Stem Cell Populations

Berthold Göttgens, Felicia S. L. Ng, B. Göttgens, 2013, Cell stem cell.

Genome-wide analysis of transcriptional regulators in human hscs reveals a densely interconnected network of coding and non-coding genes

Berthold Göttgens, Dominik Beck, Dilmi Perera, 2013 .

Transcriptional regulation of haematopoietic transcription factors

Berthold Göttgens, Nicola K. Wilson, B. Göttgens, 2011, Stem Cell Research & Therapy.

ConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sites

Jaap Heringa, Berthold Göttgens, Maurits J. J. Dijkstra, 2015, Nucleic acids research.

Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprinting.

Berthold Göttgens, Frank Grützner, Jane Rogers, 2003, Genomics.

Assessing the reliability of spike-in normalization for analyses of single-cell RNA sequencing data

Berthold Göttgens, John C Marioni, Aaron T L Lun, 2017, bioRxiv.

Decoding the development of the blood and immune systems during human fetal liver haematopoiesis

Jaume Bacardit, Sarah A. Teichmann, Berthold Göttgens, 2019, bioRxiv.

The Human Cell Atlas

Roland Eils, Alexander van Oudenaarden, Hans Clevers, 2017, bioRxiv.

Motif-blind, genome-wide discovery of cis-regulatory modules in Drosophila and mouse.

Diego Miranda-Saavedra, Berthold Göttgens, Marc S. Halfon, 2009, Developmental cell.

Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis

Sarah A. Teichmann, Berthold Göttgens, Aleksandra A. Kolodziejczyk, 2014, Cell reports.

ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.

Berthold Göttgens, Shai Izraeli, Yoram Groner, 2011, Blood.

Transcriptional regulation of haematopoietic stem cells.

Berthold Göttgens, B. Göttgens, A. Wilkinson, 2013, Advances in experimental medicine and biology.

Gene set control analysis predicts hematopoietic control mechanisms from genome-wide transcription factor binding data

Anagha Joshi, Berthold Göttgens, Rebecca Hannah, 2013, Experimental hematology.

Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci.

Berthold Göttgens, Bjarne Knudsen, Jane Rogers, 2002, Genome research.

Gene regulatory networks governing haematopoietic stem cell development and identity.

Berthold Göttgens, B. Göttgens, J. Pimanda, 2010, The International journal of developmental biology.

Regulation of the stem cell leukemia (SCL) gene: A tale of two fishes

Berthold Göttgens, James G. R. Gilbert, Roger Patient, 2001, Proceedings of the National Academy of Sciences of the United States of America.