Longqin Hu

发表

Discovery of mobocertinib, a new irreversible tyrosine kinase inhibitor indicated for the treatment of non-small-cell lung cancer harboring EGFR exon 20 insertion mutations

Daniel Lam, Longqin Hu, Jun Wang, 2022, Medicinal Chemistry Research.

Nrf2 activation through the inhibition of Keap1–Nrf2 protein–protein interaction

Longqin Hu, S. Lee, Longqin Hu, 2020, Medicinal Chemistry Research.

Discovery of direct inhibitors of Keap1–Nrf2 protein–protein interaction as potential therapeutic and preventive agents

Longqin Hu, Haifa Albanyan, Dhulfiqar Ali Abed, 2015, Acta pharmaceutica Sinica. B.

Immunomodulators targeting the PD‐1/PD‐L1 protein‐protein interaction: From antibodies to small molecules

Longqin Hu, Jeffrey Yang, Longqin Hu, 2018, Medicinal research reviews.

Targeted Prodrug Approaches for Hormone Refractory Prostate Cancer

Longqin Hu, Herve Aloysius, Longqin Hu, 2015, Medicinal research reviews.

Design, synthesis, and structure–activity relationships of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as inhibitors of the programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) immune checkpoint pathway

Longqin Hu, Jeffrey Yang, S. Basu, 2022, Medicinal Chemistry Research.

Design, synthesis, evaluation and structural studies of C2-symmetric small molecule inhibitors of the programmed cell death-1/programmed death-ligand 1 (PD-1/PD-L1) protein-protein interaction.

T. Holak, L. Skalniak, B. Musielak, 2019, Journal of medicinal chemistry.

Structure-activity relationships of 1,4-bis(arylsulfonamido)-benzene or naphthalene-N,N'-diacetic acids with varying C2-substituents as inhibitors of Keap1-Nrf2 protein-protein interaction.

Longqin Hu, M. Verzi, Sumi Lee, 2022, European journal of medicinal chemistry.

Insects: an underrepresented resource for the discovery of biologically active natural products

Longqin Hu, L. Seabrooks, Longqin Hu, 2017, Acta pharmaceutica Sinica. B.

Synthesis and evaluation of new peptide-linked doxorubicin conjugates as prodrugs activated by prostate-specific antigen

Longqin Hu, Herve Aloysius, Longqin Hu, 2020, Medicinal Chemistry Research.

Synthesis and evaluation of new 4-peptidamido-2-fluorobenzyl phosphoramide mustard conjugates as prodrugs activated by prostate-specific antigen

Longqin Hu, Herve Aloysius, Longqin Hu, 2020, Medicinal Chemistry Research.

Kinetic Analyses of Keap1–Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance

A. Kong, Longqin Hu, L. Beamer, 2011, Chemical biology & drug design.