Vijay T. Ahuja

发表

Vijay T. Ahuja, 1996 .

Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation

Vijay T. Ahuja, Yue-Zhong Shu, Harvey Wong, 2010, Drug Metabolism and Disposition.

Effect of repeated dosing on rifampin exposure in BALB/c mice.

Vijay T. Ahuja, S. Ganguly, J. Reddy, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.

Alan G. E. Wilson, Vijay T. Ahuja, Y. Liu, 2015, Bioorganic & medicinal chemistry letters.

In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists.

Vijay T. Ahuja, J. Macor, H. Wong, 2009, Journal of medicinal chemistry.

Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.

Vijay T. Ahuja, Derek J. Norris, J. Tokarski, 2021, Journal of medicinal chemistry.

Synthesis and evaluation of carbamate and aryl ether substituted pyrazinones as corticotropin releasing factor-1 (CRF₁) receptor antagonists.

Vijay T. Ahuja, J. Macor, T. Molski, 2016, Bioorganic & medicinal chemistry letters.

Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.

Alan S. Futran, Vijay T. Ahuja, Shana L. Posy, 2022, Journal of medicinal chemistry.

A strategy to minimize reactive metabolite formation: discovery of (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a potent, orally bioavailable corticotropin-releasing factor-1 receptor antagonist.

Vijay T. Ahuja, J. Macor, Y. Shu, 2009, Journal of medicinal chemistry.

Synthesis and evaluation of prodrugs of corticotropin-releasing factor-1 (CRF1) receptor antagonist BMS-665053 leading to improved oral bioavailability.

Vijay T. Ahuja, J. Macor, N. Lodge, 2017, Bioorganic & medicinal chemistry letters.

An Efficient, Direct Bis-ortho-chlorination of 4-(Difluoromethoxy)aniline and Its Application to the Synthesis of BMS-665053, a Potent and Selective Pyrazinone-Containing Corticotropin-Releasing Factor-1 Receptor Antagonist

Vijay T. Ahuja, J. Barrish, A. Mathur, 2012 .

Discovery of Pyridazinone and Pyrazolo[1,5-a]pyridine Inhibitors of C-Terminal Src Kinase.

Vijay T. Ahuja, J. Tokarski, D. Xie, 2019, ACS medicinal chemistry letters.

Design, Synthesis, and Biological Evaluation of 1,2,3,7-Tetrahydro-6H-purin-6-one and 3,7-Dihydro-1H-purine-2,6-dione Derivatives as Corticotropin-Releasing Factor1 Receptor Antagonists

Vijay T. Ahuja, K. K. Nanda, G. Trainor, 2004 .

Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors.

Vijay T. Ahuja, J. Macor, S. E. Kiefer, 2022, Journal of medicinal chemistry.

Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.

Vijay T. Ahuja, D. Ogg, P. Boriack-Sjodin, 2014, Bioorganic & medicinal chemistry letters.

Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.

Vijay T. Ahuja, D. Ogg, J. Tucker, 2013, Journal of medicinal chemistry.

Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.

Vijay T. Ahuja, A. Srivastava, A. Narayan, 2013, Journal of medicinal chemistry.

In Vitro and In Vivo Efficacy of β-Lactams against Replicating and Slowly Growing/Nonreplicating Mycobacterium tuberculosis

Vijay T. Ahuja, V. Ramachandran, R. Shandil, 2013, Antimicrobial Agents and Chemotherapy.

Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.

Vijay T. Ahuja, J. Macor, L. Bristow, 2021, Journal of medicinal chemistry.

Design, Structure-Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2-b]pyridazines as Glycogen Synthase Kinase-3β (GSK-3β) Inhibitors.

Vijay T. Ahuja, J. Macor, K. Kish, 2023, Journal of medicinal chemistry.

Identification and mitigation of a reactive metabolite liability associated with aminoimidazoles.

Vijay T. Ahuja, A. Srivastava, V. Hosagrahara, 2014, Chemical research in toxicology.

Potential CRF1R PET imaging agents: 1-fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones.

Vijay T. Ahuja, J. Macor, D. Zuev, 2013, Bioorganic & medicinal chemistry letters.

[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: introduction of N3-phenylpyrazinones as potential CRF-R1 PET imaging agents.

Vijay T. Ahuja, J. Macor, T. Molski, 2012, Bioorganic & medicinal chemistry letters.

Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors.

Vijay T. Ahuja, J. Tokarski, J. Macor, 2023, Journal of medicinal chemistry.

Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation

Vijay T. Ahuja, J. Macor, J. Leet, 2010, Drug Metabolism and Disposition.

Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists.

Joseph Payne, Vijay T. Ahuja, Yue-Zhong Shu, 2009, Journal of medicinal chemistry.

COMPARATIVE BIOTRANSFORMATION OF PYRAZINONE-CONTAINING CORTICOTROPIN-RELEASING FACTOR RECEPTOR-1 (CRF-R1) ANTAGONISTS: MINIMIZING THE REACTIVE METABOLITE FORMATION

Vijay T. Ahuja, J. Macor, Stella Huang, 2009 .

In vitro and in vivo efficacy of beta-lactams against replicating and slowly 1 growing/non replicating M. tuberculosis 2

Vijay T. Ahuja, V. Ramachandran, R. Shandil, 2013 .

Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.

Alan G. E. Wilson, Vijay T. Ahuja, Y. Liu, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists.

Vijay T. Ahuja, J. Macor, T. Molski, 2010, Bioorganic & medicinal chemistry letters.