Sarah E. Ewald

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Automated Spatially Targeted Optical Micro Proteomics (autoSTOMP) to determine protein complexity of subcellular structures

Bocheng Yin, Roberto C Mendez, Xiaoyu Zhao, 2019, bioRxiv.

Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.

Sarah E. Ewald, G. Barton, Nicholas Arpaia, 2011, Immunity.

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

Sarah E. Ewald, G. Barton, H. Chapman, 2008, Nature.

Immunoregulatory Role of NK Cells in Tissue Inflammation and Regeneration

Sarah E. Ewald, A. Tosello-Trampont, Fionna A. Surette, 2017, Front. Immunol..

Myeloid-mediated IL-1R signaling in immuno-responsive Thy-1 negative fibroblasts is critical for pulmonary fibrosis

Sarah E. Ewald, T. Barker, Chiuan-Ren Yeh, 2021, bioRxiv.

Disease Tolerance in Toxoplasma Infection

Sarah E. Ewald, S. Melchor, 2019, Front. Cell. Infect. Microbiol..

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase

Sarah E. Ewald, M. Bogyo, Jiyoun Lee, 2011, The Journal of experimental medicine.

Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice

Sarah E. Ewald, J. Boothroyd, D. Bouley, 2018, bioRxiv.

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Sarah E. Ewald, 2010 .

The Myeloid Receptor PILRβ Mediates the Balance of Inflammatory Responses through Regulation of IL-27 Production

Sarah E. Ewald, T. Mcclanahan, C. Tato, 2012, PloS one.

The molecular biology and immune control of chronic Toxoplasma gondii infection.

Sarah E. Ewald, Xiao-Yu Zhao, 2020, The Journal of clinical investigation.

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

Sarah E. Ewald, J. Boothroyd, J. Boyle, 2014, PLoS biology.

Nucleic acid recognition by the innate immune system.

Sarah E. Ewald, G. Barton, Maria L. Mouchess, 2011, Annual review of immunology.

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia

Sarah E. Ewald, T. Fox, S. Melchor, 2022, bioRxiv.

T. gondii infection induces IL-1R dependent chronic cachexia and perivascular fibrosis in the liver and skeletal muscle

Sarah E. Ewald, T. Barker, K. Byrnes, 2020, Scientific Reports.

IL-1R Regulates Disease Tolerance and Cachexia in Toxoplasma gondii Infection

Sarah E. Ewald, K. Byrnes, S. Coutermarsh-Ott, 2020, The Journal of Immunology.

NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii

Sarah E. Ewald, J. Boothroyd, Joseph Chavarria-Smith, 2013, Infection and Immunity.

Automated Spatially Targeted Optical Microproteomics Investigates Inflammatory Lesions In Situ

Sarah E. Ewald, J. Holmes, E. McGowan, 2021, Journal of proteome research.

Automated Spatially Targeted Optical Micro Proteomics (AutoSTOMP) 2.0 identifies proteins enriched within inflammatory lesions in tissue sections and human clinical biopsies

Sarah E. Ewald, E. McGowan, Rung‐chi Li, 2021, bioRxiv.

Nucleic acid sensing Toll-like receptors in autoimmunity.

Sarah E. Ewald, G. Barton, 2011, Current opinion in immunology.

Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization

Sarah E. Ewald, L. Game, Calvin Tiengwe, 2022, bioRxiv.

Cachexia and fibrosis are costs of chronic IL-1R-mediated disease tolerance in T. gondii infection

Sarah E. Ewald, T. Barker, K. Byrnes, 2019, bioRxiv.

Automated Spatially Targeted Optical Micro Proteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures.

Sarah E. Ewald, Rishi Rakhit, Bocheng Yin, 2019, Analytical chemistry.

Microbial Pathogenesis in the Era of Spatial Omics

Sarah E. Ewald, D. May, S. Lempke, 2023, Infection and immunity.

Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated T. gondii restriction in murine macrophages via vacuole nitration and intravacuolar network collapse

Sarah E. Ewald, Bocheng Yin, Xiaoyu Zhao, 2023, bioRxiv.

Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging

Sarah E. Ewald, Pankaj Kumar, Philip V Seegren, 2023, Nature Aging.

Immunoglobulin G4 in eosinophilic esophagitis: Immune complex formation and correlation with disease activity

Jeffrey M. Wilson, Sarah E. Ewald, T. Platts-Mills, 2023, Allergy.

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase

Sarah E. Ewald, M. Bogyo, Jiyoun Lee, 2011, The Journal of experimental medicine.

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase

Sarah E. Ewald, M. Bogyo, Jiyoun Lee, 2011, Journal of Experimental Medicine.

Tricarboxylic acid (TCA) cycle, sphingolipid, phosphatidylcholine metabolism is dysregulated in T. gondii infection-induced cachexia

Sarah E. Ewald, S. Melchor, M. Kester, 2022 .

Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.

Sarah E. Ewald, G. Barton, Nicholas Arpaia, 2011, Immunity.

Phosphorylation of Toxoplasma gondii Secreted Proteins during Acute and Chronic Stages of Infection

Sarah E. Ewald, L. Collinson, A. Snijders, 2020, mSphere.

Differential protein phosphorylation affects the localisation of two secreted Toxoplasma proteins and is widespread during stage conversion

Sarah E. Ewald, L. Collinson, V. Carruthers, 2020, bioRxiv.