Christopher J Schofield

发表

MeLAD: an integrated resource for metalloenzyme-ligand associations

Chen Fu, Cheng Huang, Gen Li, 2019, Bioinform..

The Inhibitor Thiomandelic Acid Binds to Both Metal Ions in Metallo-β-lactamase and Induces Positive Cooperativity in Metal Binding*

Lars Olsen, Gordon C K Roberts, Mikael Jensen, 2003, Journal of Biological Chemistry.

Identification of a pathogenic FTO mutation by next-generation sequencing in a newborn with growth retardation and developmental delay

Hwanho Choi, Michael A McDonough, Christopher J Schofield, 2015, Journal of Medical Genetics.

Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism.

Christopher J Schofield, Stuart C. Wilson, C. Schofield, 2005, Organic & biomolecular chemistry.

Mechanistic Studies on Three 2-Oxoglutarate-dependent Oxygenases of Flavonoid Biosynthesis

Kazuki Saito, Christopher J Schofield, Mami Yamazaki, 2004, Journal of Biological Chemistry.

Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases.

Christopher J Schofield, C. Schofield, T. Leissing, 2016, Current opinion in structural biology.

Glyco- and peptidomimetics from three-component Joullié-Ugi coupling show selective antiviral activity.

Benjamin G Davis, Christopher J Schofield, B. G. Davis, 2005, Journal of the American Chemical Society.

A comparison of 2‐hydroxyglutarate detection at 3 and 7 T with long‐TE semi‐LASER

Peter Jezzard, Stuart Clare, Olaf Ansorge, 2018, NMR in biomedicine.

Crystal Structure of Carbapenem Synthase (CarC)*

Maya Topf, Christopher J Schofield, M. Topf, 2003, Journal of Biological Chemistry.

Expanding chemical biology of 2-oxoglutarate oxygenases.

Christopher J Schofield, C. Schofield, Christoph Loenarz, 2008, Nature chemical biology.

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

David I Stuart, Christopher J Schofield, Michael I. Wilson, 2002, Nature.

On the histone lysine methyltransferase activity of fungal metabolite chaetocin.

Peter A DiMaggio, Peter A. DiMaggio, Christopher J Schofield, 2013, Journal of medicinal chemistry.

Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation.

Tom Brown, Christopher J Schofield, T. Brown, 2011, Chemical communications.

Crystal structure of a clavaminate synthase–Fe(II)–2‐oxoglutarate–substrate–NO complex: evidence for metal centred rearrangements

Christopher J Schofield, Karl Harlos, K. Harlos, 2002, FEBS letters.

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N6-Methyladenosine RNA Demethylation*

Wolfram Tempel, Chao Xu, Christopher J Schofield, 2014, The Journal of Biological Chemistry.

Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors.

Christopher J Schofield, Moreno Galleni, J. Frère, 2008, Journal of medicinal chemistry.

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

Michael A McDonough, Christopher J Schofield, P. Ratcliffe, 2012, Angewandte Chemie.

The unusual bifunctional catalysis of epimerization and desaturation by carbapenem synthase.

Maya Topf, Leo Radom, Christopher J Schofield, 2004, Journal of the American Chemical Society.

Signalling hypoxia by HIF hydroxylases.

Christopher J Schofield, P. Ratcliffe, C. Schofield, 2005, Biochemical and biophysical research communications.

Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family*

Christopher J Schofield, Neil J Oldham, S. Bhattacharya, 2002, The Journal of Biological Chemistry.

Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.

Akane Kawamura, Christopher J Schofield, C. Schofield, 2013, Journal of medicinal chemistry.

Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases.

Michael A McDonough, Christopher J Schofield, C. Schofield, 2012, Current opinion in structural biology.

Structural basis for inhibition of the fat mass and obesity associated protein (FTO).

Michael A McDonough, Christopher J Schofield, Eleanor A. L. Bagg, 2013, Journal of medicinal chemistry.

Biosynthesis of Carbapenem Antibiotics: New Carbapenam Substrates for Carbapenem Synthase (CarC)

Christopher J Schofield, Barrie Kellam, C. Schofield, 2004, Chembiochem : a European journal of chemical biology.

Recent Progress in Histone Demethylase Inhibitors.

Akane Kawamura, Christopher J Schofield, Paul E Brennan, 2016, Journal of medicinal chemistry.

Structural insights into how 5-hydroxymethylation influences transcription factor binding.

Tom Brown, Michael A McDonough, Christopher J Schofield, 2014, Chemical communications.

Fast and forceful refolding of stretched alpha-helical solenoid proteins.

Khadar Abdi, Vann Bennett, Christopher J Schofield, 2010, Biophysical journal.

The enzymes of β-lactam biosynthesis.

Michael A McDonough, Christopher J Schofield, C. Schofield, 2013, Natural product reports.

Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations.

Peter Jezzard, Stuart Clare, Olaf Ansorge, 2016, Cancer research.

Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase.

Michael A McDonough, Christopher J Schofield, Sergey N Krylov, 2012, Journal of medicinal chemistry.