Nadine Becker

发表

iPS細胞由来心筋細胞(hiPSC‐CMS)を使用したソフォスブビル・アミオダロン同時投与による細胞電気生理,Ca2+調節および興奮収縮連関障害のin vivoでの再現

Daniel C. Millard, Niels Fertig, Coby B. Carlson, 2016 .

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

James Kramer, David G Strauss, Liudmila Polonchuk, 2020, Toxicology and applied pharmacology.

Complementary automated patch clamp, extracellular field potential and impedance recordings of iPSCs: Safety screening tool box for the future

Michael George, Daniel C. Millard, Niels Fertig, 2016 .

Minimized cell usage for stem cell-derived and primary cells on an automated patch clamp system.

Ralf Kettenhofen, Heribert Bohlen, Michael George, 2013, Journal of pharmacological and toxicological methods.

A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.

James Kramer, David G Strauss, George Okeyo, 2020, Journal of pharmacological and toxicological methods.

Unattended screening workflow in a 384-well automated patch clamp system

Claudia Haarmann, Niels Fertig, Sonja Stoelzle-Feix, 2021, Journal of Pharmacological and Toxicological Methods.

Unattended Drug Discovery Screening Workflow in a 384-Well Automated Patch Clamp System

James Costantin, Claudia Haarmann, Niels Fertig, 2021 .

Reliable identification of heart disease in drug discovery using automated patch clamps: Benchmarking best practices and calibration criteria for improved proarrhythmic assessment

Søren Friis, Niels Fertig, Sonja Stoelzle-Feix, 2021, Journal of Pharmacological and Toxicological Methods.

Safety pharmacology studies using EFP and impedance.

Michael George, Niels Fertig, Nadine Becker, 2016, Journal of pharmacological and toxicological methods.

Automated Patch Clamp Recordings of Human Stem Cell-Derived Cardiomyocytes

Michael George, Andrea Brüggemann, Claudia Haarmann, 2017 .

Automated Patch Clamp Meets High-Throughput Screening

Michael George, Andrea Brüggemann, Claudia Haarmann, 2016, Journal of laboratory automation.

Novel screening techniques for ion channel targeting drugs

Andrea Brüggemann, Niels Fertig, Nadine Becker, 2015, Channels.

An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery

Michael George, Søren Friis, Andrea Brüggemann, 2018, Expert opinion on drug discovery.