Annette Kopp-Schneider

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Power gains by using external information in clinical trials are typically not possible when requiring strict type I error control

Annette Kopp-Schneider, Silvia Calderazzo, Manuel Wiesenfarth, 2019, Biometrical journal. Biometrische Zeitschrift.

Comparative validation of multi-instance instrument segmentation in endoscopy: Results of the ROBUST-MIS 2019 challenge

Klaus H. Maier-Hein, Pheng-Ann Heng, Lena Maier-Hein, 2020, Medical Image Anal..

Can Biologically Based Models of Carcinogenesis Be Used for Risk Assessment

Annette Kopp-Schneider, A. Kopp-Schneider, 2002 .

Why rankings of biomedical image analysis competitions should be interpreted with care

Alejandro F. Frangi, Peter F. Neher, Aaron Carass, 2018, Nature Communications.

Optimal experimental designs for estimating the drug combination index in toxicology

Annette Kopp-Schneider, T. Holland-Letz, T. Holland-Letz, 2018, Comput. Stat. Data Anal..

Design of a testing strategy using non-animal based test methods: lessons learnt from the ACuteTox project.

Annette Kopp-Schneider, Pilar Prieto, Agnieszka Kinsner-Ovaskainen, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Statistical strategies for averaging EC50 from multiple dose–response experiments

Annette Kopp-Schneider, Xiaoqi Jiang, 2014, Archives of Toxicology.

COMPARING METHODS FOR ASSESSING AGREEMENT IN RADIOLOGICAL STUDIES WITH CONTINUOUS OUTCOME

Annette Kopp-Schneider, Michael Fabel, Marc Weimer, 2008 .

Summarizing EC50 estimates from multiple dose‐response experiments: A comparison of a meta‐analysis strategy to a mixed‐effects model approach

Annette Kopp-Schneider, Xiaoqi Jiang, A. Kopp-Schneider, 2014, Biometrical journal. Biometrische Zeitschrift.

Exploratory identification of predictive biomarkers in randomized trials with normal endpoints

Axel Benner, Annette Kopp-Schneider, Julia Krzykalla, 2019, Statistics in medicine.

Clustering of samples and variables with mixed-type data

Annette Kopp-Schneider, Manuela Hummel, Dominic Edelmann, 2017, PloS one.

Biomedical Image Analysis Challenges (BIAS) Reporting Guideline

Lena Maier-Hein, Annika Reinke, Matthias Eisenmann, 2020 .

Methods and open-source toolkit for analyzing and visualizing challenge results pdf

Lena Maier-Hein, Annika Reinke, Manuel Jorge Cardoso, 2019, Scientific reports.

Robust Medical Instrument Segmentation Challenge 2019 pdf

Klaus H. Maier-Hein, Lena Maier-Hein, Martin Wagner, 2020, ArXiv.

Addressing small sample size bias in multiple-biomarker trials: Inclusion of biomarker-negative patients and Firth correction.

Axel Benner, Annette Kopp-Schneider, Christina Habermehl, 2018, Biometrical journal. Biometrische Zeitschrift.

The design heatmap: A simple visualization of D ‐optimality design problems

Annette Kopp-Schneider, Tim Holland-Letz, T. Holland-Letz, 2020, Biometrical journal. Biometrische Zeitschrift.

Robust biclustering by sparse singular value decomposition incorporating stability selection

Martin Sill, Axel Benner, Annette Kopp-Schneider, 2011, Bioinform..

"ToxRTool", a new tool to assess the reliability of toxicological data.

Thomas Hartung, Klaus Schneider, Annette Kopp-Schneider, 2009, Toxicology letters.

Is the winner really the best? A critical analysis of common research practice in biomedical image analysis competitions pdf

Alejandro F. Frangi, Peter F. Neher, Klaus H. Maier-Hein, 2018, ArXiv.

A large annotated medical image dataset for the development and evaluation of segmentation algorithms pdf

Ronald M. Summers, M. Jorge Cardoso, Lena Maier-Hein, 2019, ArXiv.

Functional analysis of high-content high-throughput imaging data

Annette Kopp-Schneider, Bob van de Water, Xiaoqi Jiang, 2017 .

Prediction accuracy and variable selection for penalized cause‐specific hazards models

Axel Benner, Annette Kopp-Schneider, Maral Saadati, 2018, Biometrical journal. Biometrische Zeitschrift.

Why rankings of biomedical image analysis competitions should be interpreted with care

Aaron Carass, Keno März, Lena Maier-Hein, 2018, Nature Communications.

Report of the EPAA–ECVAM Workshop on the Validation of Integrated Testing Strategies (ITS)

Valérie Zuang, Andrew Worth, Silvia Casati, 2012, Alternatives to laboratory animals : ATLA.

How to Exploit Weaknesses in Biomedical Challenge Design and Organization

Lena Maier-Hein, Annika Reinke, Patrick Scholz, 2018, MICCAI.

A decision-theoretic approach to Bayesian clinical trial design and evaluation of robustness to prior-data conflict

Annette Kopp-Schneider, Silvia Calderazzo, Manuel Wiesenfarth, 2020, Biostatistics.

Data management in large-scale collaborative toxicity studies: how to file experimental data for automated statistical analysis.

Annette Kopp-Schneider, Sven Stanzel, Marc Weimer, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Optimal experimental designs for dose–response studies with continuous endpoints

Annette Kopp-Schneider, Tim Holland-Letz, T. Holland-Letz, 2014, Archives of Toxicology.

Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions—A calibration approach

Annette Kopp-Schneider, Manuel Wiesenfarth, Ulrich Abel, 2018, Biometrical journal. Biometrische Zeitschrift.

On the identification of predictive biomarkers: Detecting treatment-by-gene interaction in high-dimensional data

Axel Benner, Annette Kopp-Schneider, Wiebke Werft, 2012, Comput. Stat. Data Anal..

Author Correction: Why rankings of biomedical image analysis competitions should be interpreted with care

Aaron Carass, Keno März, Lena Maier-Hein, 2019, Nature Communications.

Visualization of Parametric Carcinogenesis Models

Annette Kopp-Schneider, Jutta Groos, 2004 .

BIAS: Transparent reporting of biomedical image analysis challenges

Lena Maier-Hein, Annika Reinke, Matthias Eisenmann, 2019, Medical Image Analysis.

How can we learn (more) from challenges? A statistical approach to driving future algorithm development pdf

Lena Maier-Hein, Annika Reinke, Pierangela Bruno, 2021, ArXiv.

Common Limitations of Image Processing Metrics: A Picture Story pdf

Ronald M. Summers, Sotirios A. Tsaftaris, Lena Maier-Hein, 2021, ArXiv.

Machine learning-based analysis of hyperspectral images for automated sepsis diagnosis pdf

Lena Maier-Hein, Silvia Seidlitz, Beat P. Müller-Stich, 2021, ArXiv.

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

Barbara Hero, Annette Kopp-Schneider, Andreas von Deimling, 2009, Clinical Cancer Research.

Absolute number of new lesions on 18F-FDG PET/CT is more predictive of clinical response than SUV changes in metastatic melanoma patients receiving ipilimumab

Annette Kopp-Schneider, Uwe Haberkorn, Antonia Dimitrakopoulou-Strauss, 2018, European Journal of Nuclear Medicine and Molecular Imaging.

Quantitative in vitro to in vivo extrapolation of tissues toxicity.

Annette Kopp-Schneider, Arno Lukas, Masoud Jamei, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Changes of prostate gland volume with and without androgen deprivation after intensity modulated radiotherapy - A follow-up study.

Annette Kopp-Schneider, Stefan Delorme, Christian Thieke, 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

CluMix : Clustering and Visualization of Mixed-Type Data

Annette Kopp-Schneider, Manuela Hummel, Dominic Edelmann, 2017 .

Stochastic Carcinogenesis Models

Annette Kopp-Schneider, Iris Burkholder, Jutta Groos, 2006 .

Optimization and prevalidation of the in vitro ERalpha CALUX method to test estrogenic and antiestrogenic activity of compounds.

Juliette Legler, Hilda Witters, Annette Kopp-Schneider, 2010, Reproductive toxicology.

Validation of Fourier decomposition MRI with dynamic contrast-enhanced MRI using visual and automated scoring of pulmonary perfusion in young cystic fibrosis patients.

Annette Kopp-Schneider, Tobias Heimann, Grzegorz Bauman, 2013, European journal of radiology.

Intrinsic Gating for Small-Animal Computed Tomography: A Robust ECG-Less Paradigm for Deriving Cardiac Phase Information and Functional Imaging

Wolfhard Semmler, Fabian Kiessling, Annette Kopp-Schneider, 2008, Circulation. Cardiovascular imaging.

Multimodal hypoxia imaging and intensity modulated radiation therapy for unresectable non-small-cell lung cancer: the HIL trial

Gregor Sommer, Bram Stieltjes, Annette Kopp-Schneider, 2012, Radiation oncology.

The impact of data transformations on concentration-response modeling.

Annette Kopp-Schneider, Marc Weimer, Xiaoqi Jiang, 2012, Toxicology letters.

The role of interim 18F-FDG PET/CT in prediction of response to ipilimumab treatment in metastatic melanoma

Annette Kopp-Schneider, Uwe Haberkorn, Antonia Dimitrakopoulou-Strauss, 2018, European Journal of Nuclear Medicine and Molecular Imaging.

Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology

Tim Holland-Letz, Annette Kopp-Schneider, T. Holland-Letz, 2018, Journal of biopharmaceutical statistics.

Longitudinal studies of the 18F-FDG kinetics after ipilimumab treatment in metastatic melanoma patients based on dynamic FDG PET/CT

Annette Kopp-Schneider, Uwe Haberkorn, Antonia Dimitrakopoulou-Strauss, 2018, Cancer Immunology, Immunotherapy.

Morphologic and functional scoring of cystic fibrosis lung disease using MRI.

Annette Kopp-Schneider, Jürgen Biederer, Christian Hintze, 2012, European journal of radiology.

Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures

Annette Kopp-Schneider, Arno Lukas, Philip G Hewitt, 2013, Drug Metabolism and Disposition.

Comparison of software tools to improve the detection of carcinogen induced changes in the rat liver proteome by analyzing SELDI-TOF-MS spectra.

Annette Kopp-Schneider, Carina Ittrich, Juergen Hellmann, 2006, Journal of proteome research.

Dose-Response Modeling

Annette Kopp-Schneider, Lutz Edler, Harald Heinzl, 2006 .

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.

Annette Kopp-Schneider, Paul Jennings, Alice Limonciel, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Assessment of thoracic aortic conformational changes by four-dimensional computed tomography angiography in patients with chronic aortic dissection type b

Annette Kopp-Schneider, Hans-Ulrich Kauczor, Dittmar Böckler, 2008, European Radiology.

Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study.

Annette Kopp-Schneider, Paul Jennings, Alice Limonciel, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies

Michael Platten, Annette Kopp-Schneider, Stefan M. Pfister, 2020, BMC Cancer.

4D-CT-based target volume definition in stereotactic radiotherapy of lung tumours: comparison with a conventional technique using individual margins.

Annette Kopp-Schneider, Jürgen Debus, Bernhard Rhein, 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.