Patrick R. Cushing

发表

Design of Protein-Protein Interactions with a Novel Ensemble-Based Scoring Algorithm

Bruce Randall Donald, Prisca Boisguerin, Kyle E. Roberts, 2011, RECOMB.

Computational Design of a PDZ Domain Peptide Inhibitor that Rescues CFTR Activity

Bruce Randall Donald, Prisca Boisguerin, Kyle E. Roberts, 2012, PLoS Comput. Biol..

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant‐negative, or hypomorphic alleles

Patrick R. Cushing, Caroline L. Speck, S. Griffey, 2007, The EMBO journal.

Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses.

Patrick R. Cushing, J. F. Amacher, D. Madden, 2014, Structure.

The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling.

Patrick R. Cushing, D. Madden, P. Boisguérin, 2008, Biochemistry.

Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor.

Patrick R. Cushing, J. Weiner, D. Madden, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Hybrid organic-inorganic inhibitors of a PDZ interaction that regulates the endocytic fate of CFTR.

Patrick R. Cushing, D. Madden, Rituparna Kundu, 2012, Angewandte Chemie.

Engineering peptide inhibitors to overcome PDZ binding promiscuity.

Prisca Boisguerin, Rudolf Volkmer, Patrick R. Cushing, 2010, Angewandte Chemie.

Small Molecule Inhibition of the Na+/H+ Exchange Regulatory Factor 1 and Parathyroid Hormone 1 Receptor Interaction

Patrick R. Cushing, M. Pellegrini, D. Mierke, 2014, Biochemistry.

A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR.

Patrick R. Cushing, D. Madden, P. Boisguérin, 2010, Angewandte Chemie.

Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain

Patrick R. Cushing, S. Gerber, R. Guy, 2018, Bioscience reports.

Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains

Patrick R. Cushing, C. Bahl, D. Madden, 2012, The Journal of Biological Chemistry.

Stereochemical preferences modulate affinity and selectivity among five PDZ domains that bind CFTR: comparative structural and sequence analyses.

Patrick R. Cushing, D. Madden, P. Boisguérin, 2014, Structure.