K. G. Jensen

发表

HLW Deep Borehole Design and Assessment: Notes on Technical Performance

Michael J. Driscoll, K. G. Jensen, 2010 .

A Framework for Performance Assessment and Licensing of Deep Borehole Repositories

Michael J. Driscoll, K. G. Jensen, 2010 .

Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co‐administration of L‐tryptophan

K. G. Jensen, R. Holm, B. Brodin, 2009, British journal of pharmacology.

Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

Ursula Klingmüller, Bob van de Water, K. G. Jensen, 2019, Nature Reviews Drug Discovery.

Metabolism of phenacetin in V79 Chinese hamster cell cultures expressing rat liver cytochrome P4501A2 compared to isolated rat hepatocytes.

K. G. Jensen, S. Loft, J. Doehmer, 1993, Biochemical pharmacology.

Spindle‐inhibiting effects of organotin compounds. II. Induction of chromosomal supercontraction by di‐ and tri‐alkyl and ‐aryl compounds

K. G. Jensen, M. Rønne, O. Andersen, 1989 .

Kinetics and inhibition by fluvoxamine of phenacetin O-deethylation in V79 cells expressing human CYP1A2.

K. G. Jensen, S. Loft, J. Doehmer, 1995, Pharmacology & toxicology.

Antihypertensive activity in a series of 1-piperazino-3-phenylindans with potent 5-HT2-antagonistic activity.

K. G. Jensen, K. Bogeso, J. Hyttel, 1988, Journal of medicinal chemistry.

5-Hydroxy-L-tryptophan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination.

K. G. Jensen, R. Holm, B. Brodin, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Lack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro Methods

K. G. Jensen, C. Bundgaard, G. Chandrasena, 2017, Drug Metabolism and Disposition.

Direct and Indirect Assessment of the Aneuploidy-inducing Potency of Organotin Compounds

K. G. Jensen, M. Rønne, O. Andersen, 1991 .

Spindle-Inhibiting Effects of Organotin Compounds: Effects of Trimethyltin on Chromosome Length

K. G. Jensen, M. Rønne, O. Andersen, 1990 .

Induction of aberrant mitosis with PCBs: particular efficiency of 2, 3,3',4,4'-pentachlorobiphenyl and synergism with triphenyltin.

K. G. Jensen, E. Klasson-Wehler, A. Onfelt, 2000, Mutagenesis.

Organotin compounds induce aneuploidy in human peripheral lymphocytes in vitro.

K. G. Jensen, M. Rønne, O. Andersen, 1991, Mutation research.

Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.

Thomas Ruhland, K. G. Jensen, Morten Jørgensen, 2011, Journal of medicinal chemistry.

Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential.

K. G. Jensen, C. Christoffersen, B. Bang-Andersen, 2012, Bioorganic & medicinal chemistry letters.

Effects of organotin compounds on mitosis, spindle structure, toxicity and in vitro microtubule assembly.

K. G. Jensen, O. Andersen, M. Wallin, 1991, Mutagenesis.

Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

K. G. Jensen, Amy E. Chadwick, Dominic P. Williams, 2019, Nature Reviews Drug Discovery.

The detection and evaluation of aneugenic chemicals.

K. G. Jensen, M. Kirsch‐Volders, S. Ellard, 1996, Mutation research.

Differential effects of γ‐secretase and BACE1 inhibition on brain Aβ levels in vitro and in vivo

K. G. Jensen, L. Pedersen, C. Volbracht, 2009, Journal of neurochemistry.

Paracetamol-induced spindle disturbances in V79 cells with and without expression of human CYP1A2.

K. G. Jensen, S. Loft, J. Doehmer, 1996, Pharmacology & toxicology.

Identification of a new series of non-peptidic NK3 receptor antagonists.

K. G. Jensen, J. Kehler, N. Khanzhin, 2011, Bioorganic & medicinal chemistry letters.

SHORT COMMUNICATION: Effect of ascorbate and 5-aminosalicylic acid on light-induced 8-hydroxydeoxyguanosine formation in V79 Chinese hamster cells

K. G. Jensen, S. Loft, A. Fischer-Nielsen, 1993 .

In vitro metabolism of the M1-muscarinic agonist 5-(2-ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetrahydropyridine by human hepatic cytochromes P-450 determined at pH 7.4 and 8.5.

K. G. Jensen, L. Dalgaard, L Dalgaard, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Metabolites of [14C]-5-(2-Ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetrahydropyridine in Mice, Rats, Dogs, and Humans

K. G. Jensen, H. Pedersen, L. Dalgaard, 1999 .

Metabolites of [(14)C]-5-(2-ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3, 6-tetrahydropyridine in mice, rats, dogs, and humans.

K. G. Jensen, H. Pedersen, L. Dalgaard, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Identification of Cytochrome P450 Isoforms Involved in the Metabolism of Paroxetine and Estimation of Their Importance for Human Paroxetine Metabolism Using a Population-Based Simulator

K. G. Jensen, Kristian Linnet, Jakob Jornil, 2010, Drug Metabolism and Disposition.

Effects of benzo[a]pyrene and (+-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2.

K. G. Jensen, S. Loft, J. Doehmer, 1993, Carcinogenesis.

Discovery of novel α₁-adrenoceptor ligands based on the antipsychotic sertindole suitable for labeling as PET ligands.

K. G. Jensen, C. Christoffersen, B. Bang-Andersen, 2013, Bioorganic & medicinal chemistry.

Risk assessment of accidental nortriptyline poisoning: the importance of cytochrome P450 for nortriptyline elimination investigated using a population-based pharmacokinetic simulator.

K. G. Jensen, K. Linnet, F. Larsen, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis and SAR study of a novel series of dopamine receptor agonists.

K. G. Jensen, C. Christoffersen, B. Bang-Andersen, 2014, Bioorganic & medicinal chemistry.

Effect of ascorbate and 5-aminosalicylic acid on light-induced 8-hydroxydeoxyguanosine formation in V79 Chinese hamster cells.

K. G. Jensen, S. Loft, A. Fischer-Nielsen, 1993, Carcinogenesis.

Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.

K. G. Jensen, A. Mørk, B. Bang-Andersen, 2011, Journal of medicinal chemistry.

Synthesis and SAR study of a novel series of dopamine receptor agonists.

K. G. Jensen, C. Christoffersen, B. Bang-Andersen, 2014, Bioorganic & medicinal chemistry.