Karl A. Hassan

发表

TransportDB 2.0: a database for exploring membrane transporters in sequenced genomes from all domains of life

Ian T. Paulsen, Liam D. H. Elbourne, Sasha G. Tetu, 2016, Nucleic Acids Res..

Comparative Genomics of Plant-Associated Pseudomonas spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions

Young Cheol Kim, Edward W. Davis, Karl A. Hassan, 2012, PLoS genetics.

The Effect of Iron Limitation on the Transcriptome and Proteome of Pseudomonas fluorescens Pf-5

Ian T. Paulsen, Sasha G. Tetu, Karl A. Hassan, 2012, PloS one.

From omics to systems biology: exploring the mystery box of microbial life

Ian T. Paulsen, Martin Ostrowski, Sasha G. Tetu, 2011 .

Sequences of Two Related Multiple Antibiotic Resistance Virulence Plasmids Sharing a Unique IS26-Related Molecular Signature Isolated from Different Escherichia coli Pathotypes from Different Hosts

Ian T. Paulsen, Karl A. Hassan, I. Paulsen, 2013, PloS one.

Elucidating Essential Genes in Plant-Associated Pseudomonas protegens Pf-5 Using Transposon Insertion Sequencing

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2020, Journal of Bacteriology.

Crystal Structure of an Integron Gene Cassette-Associated Protein from Vibrio cholerae Identifies a Cationic Drug-Binding Module

Karl A. Hassan, I. Paulsen, Y. Boucher, 2011, PloS one.

The effect of zinc limitation on the transcriptome of Pseudomonas protegens Pf-5.

Karl A. Hassan, Chee Kent Lim, I. Paulsen, 2013, Environmental microbiology.

Disruption of Transporters Affiliated with Enantio-Pyochelin Biosynthesis Gene Cluster of Pseudomonas protegens Pf-5 Has Pleiotropic Effects

Karl A. Hassan, Chee Kent Lim, I. Paulsen, 2016, PloS one.

The putative drug efflux systems of the Bacillus cereus group

Karl A. Hassan, A. Kolstø, I. Paulsen, 2017, PloS one.

The Role of the CopA Copper Efflux System in Acinetobacter baumannii Virulence

Karl A. Hassan, I. Paulsen, C. McDevitt, 2019, International journal of molecular sciences.

A Transcriptomic Approach to Identify Novel Drug Efflux Pumps in Bacteria.

Karl A. Hassan, I. Paulsen, Liping Li, 2018, Methods in molecular biology.

Roles of DHA2 Family Transporters in Drug Resistance and Iron Homeostasis in Acinetobacter spp.

Karl A. Hassan, I. Paulsen, Neil L. Wilson, 2011, Journal of Molecular Microbiology and Biotechnology.

Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA.

Karl A. Hassan, R. Skurray, Melissa H. Brown, 2006, FEMS microbiology letters.

Spermidine and spermine are the natural substrates of the Acinetobacter baumannii AmvA multidrug efflux pump

Karl A. Hassan, I. Paulsen, Liping Li, 2020, bioRxiv.

pA506, a Conjugative Plasmid of the Plant Epiphyte Pseudomonas fluorescens A506

Edward W. Davis, Karl A. Hassan, I. Paulsen, 2013, Applied and Environmental Microbiology.

Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies

Karl A. Hassan, I. Paulsen, T. Rupasinghe, 2019, mBio.

The effect of root exudates on the transcriptome of rhizosphere Pseudomonas spp

Karl A. Hassan, I. Paulsen, D. Gang, 2021, bioRxiv.

Structural and Functional Analysis of the Type III Secretion System from Pseudomonas fluorescens Q8r1-96

Karl A. Hassan, I. Paulsen, L. Thomashow, 2010, Journal of bacteriology.

Physical enrichment of transposon mutants from saturation mutant libraries using the TraDISort approach

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2017, Mobile genetic elements.

Genome of alkaliphilic Bacillus pseudofirmus OF 4 reveals adaptations

D. M. Ivey, Karl A. Hassan, Masahiro Ito, 2011 .

Delving into defence: identifying the Pseudomonas protegens Pf-5 gene suite involved in defence against secreted products of fungal, oomycete and bacterial rhizosphere competitors

Karl A. Hassan, I. Paulsen, S. Tetu, 2021, Microbial genomics.

pA 506 , a Conjugative Plasmid of the Plant Epiphyte Pseudomonas fluorescens A 506

Edward W. Davis, Karl A. Hassan, I. Paulsen, 2013 .

Quantitative PCR for detection of mRNA and gDNA in environmental isolates.

Karl A. Hassan, Anthony J. Brzoska, 2014, Methods in molecular biology.

protegens Pf-5 of the Soil Bacterium Pseudomonas Effect of Tannic Acid on the Transcriptome

Karl A. Hassan, Chee Kent Lim, I. Paulsen, 2013 .

Short-chain diamines are the physiological substrates of PACE family efflux pumps

Karl A. Hassan, I. Paulsen, Liping Li, 2019, Proceedings of the National Academy of Sciences.

Fluorescence-Based Flow Sorting in Parallel with Transposon Insertion Site Sequencing Identifies Multidrug Efflux Systems in Acinetobacter baumannii

Amy K. Cain, Christine J. Boinett, Karl A. Hassan, 2016, mBio.

Functional analyses reveal an important role for tyrosine residues in the staphylococcal multidrug efflux protein QacA

Karl A. Hassan, R. Skurray, Melissa H. Brown, 2008, BMC Microbiology.

Analysis of Tryptophan Residues in the Staphylococcal Multidrug Transporter QacA Reveals Long-Distance Functional Associations of Residues on Opposite Sides of the Membrane

Karl A. Hassan, R. Skurray, Melissa H. Brown, 2008, Journal of bacteriology.

Rapid multiplexed phenotypic screening identifies drug resistance functions for three novel efflux pumps in Acinetobacter baumannii.

Karl A. Hassan, I. Paulsen, Liping Li, 2016, The Journal of antimicrobial chemotherapy.

The molecular basis of Acinetobacter baumannii cadmium toxicity and 1 resistance 2 3

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2021 .

The Molecular Basis of Acinetobacter baumannii Cadmium Toxicity and Resistance

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2020, bioRxiv.

Zinc stress induces copper depletion in Acinetobacter baumannii

Karl A. Hassan, I. Paulsen, C. McDevitt, 2017, BMC Microbiology.

Transmembrane Helix 12 of the Staphylococcus aureus Multidrug Transporter QacA Lines the Bivalent Cationic Drug Binding Pocket

Karl A. Hassan, R. Skurray, Melissa H. Brown, 2007, Journal of bacteriology.

The Membrane Composition Defines the Spatial Organization and Function of a Major Acinetobacter baumannii Drug Efflux System

Karl A. Hassan, I. Paulsen, Ingo Köper, 2021, mBio.

The Membrane Composition Defines the Spatial Organization and Function of a Major Acinetobacter baumannii Drug Efflux System

Karl A. Hassan, Mara, I. Paulsen, 2021 .

The role of zinc efflux during Acinetobacter baumannii infection.

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2020, ACS infectious diseases.

Genomic fitness profiling of Acinetobacter baumannii reveals modes of action for common biocides and mechanisms of biocide-antibiotic antagonism

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2021 .

Glycine-rich transmembrane helix 10 in the staphylococcal tetracycline transporter TetA(K) lines a solvent-accessible channel.

Karl A. Hassan, K. Robinson, R. Skurray, 2006, Biochemistry.

The Transcriptomic Signature of Tigecycline in Acinetobacter baumannii

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2020, Frontiers in Microbiology.

The Iron-chelator, N,N’-bis (2-hydroxybenzyl) Ethylenediamine-N,N’-diacetic acid is an Effective Colistin Adjunct against Clinical Strains of Biofilm-Dwelling Pseudomonas aeruginosa

Karl A. Hassan, I. Lamont, D. Reid, 2020, Antibiotics.

Complete Genome Sequence of Rhodococcus sp. Strain 9, Isolated from Contaminated Australian Groundwater

Karl A. Hassan, M. Megharaj, S. Subashchandrabose, 2022, Microbiology resource announcements.

Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens

Karl A. Hassan, A. Goldman, I. Paulsen, 2018, Research in microbiology.

Pacing across the membrane: the novel PACE family of ef ﬂ ux pumps is widespread in Gram-negative pathogens Research in Microbiology

Karl A. Hassan, A. Goldman, I. Paulsen, 2018 .

Comparative analysis of surface-exposed virulence factors of Acinetobacter baumannii

Karl A. Hassan, I. Paulsen, U. H. Stroeher, 2014, BMC Genomics.

Transcriptomic and biochemical analyses identify a family of chlorhexidine efflux proteins

Karl A. Hassan, I. Paulsen, P. Henderson, 2013, Proceedings of the National Academy of Sciences.

Adherence and motility characteristics of clinical Acinetobacter baumannii isolates.

Karl A. Hassan, I. Paulsen, U. H. Stroeher, 2011, FEMS microbiology letters.

Active Export Proteins Mediating Drug Resistance in Staphylococci

Karl A. Hassan, R. Skurray, Melissa H. Brown, 2007, Journal of Molecular Microbiology and Biotechnology.

Breaching the Barrier: Genome-Wide Investigation into the Role of a Primary Amine in Promoting E. coli Outer-Membrane Passage and Growth Inhibition by Ampicillin

Amy K. Cain, Karl A. Hassan, R. Maharjan, 2022, Microbiology spectrum.

Under the Microscope Pumping out biocides – cause for concern ?

Karl A. Hassan, I. Paulsen, Melissa H. Brown, 2012 .

Pumping out biocides – cause for concern

Karl A. Hassan, I. Paulsen, Melissa H. Brown, 2010 .

SecDF as Part of the Sec-Translocase Facilitates Efficient Secretion of Bacillus cereus Toxins and Cell Wall-Associated Proteins

Karl A. Hassan, A. Kolstø, I. Paulsen, 2014, PloS one.

Resistance to pentamidine is mediated by AdeAB, regulated by AdeRS, and influenced by growth conditions in Acinetobacter baumannii ATCC 17978

Karl A. Hassan, U. H. Stroeher, Shashikanth Marri, 2018, bioRxiv.

Evolution of RND efflux pumps in the development of a successful pathogen.

Karl A. Hassan, I. Paulsen, L. Elbourne, 2022, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Cross-protection and cross-feeding between Klebsiella pneumoniae and Acinetobacter baumannii promotes their co-existence

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2023, Nature Communications.

Bacillus cereus eﬄux protein BC3310 – a multidrug transporter of the unknown major facilitator family, UMF-2

Karl A. Hassan, A. Kolstø, I. Paulsen, 2015, Front. Microbiol..

Root Exudates Alter the Expression of Diverse Metabolic, Transport, Regulatory, and Stress Response Genes in Rhizosphere Pseudomonas

Karl A. Hassan, I. Paulsen, D. Gang, 2021, Frontiers in Microbiology.

TransAAP: an automated annotation pipeline for membrane transporter prediction in bacterial genomes

Karl A. Hassan, I. Paulsen, L. Elbourne, 2023, Microbial genomics.

The Complete Genome and Phenome of a Community-Acquired Acinetobacter baumannii

Karl A. Hassan, I. Paulsen, L. Elbourne, 2013, PloS one.

Insights on virulence from the complete genome of Staphylococcus capitis

Karl A. Hassan, I. Paulsen, A. Peleg, 2015, Front. Microbiol..

Optimized production and analysis of the staphylococcal multidrug efflux protein QacA.

Karl A. Hassan, R. Brennan, R. Skurray, 2009, Protein expression and purification.

H-NS Plays a Role in Expression of Acinetobacter baumannii Virulence Features

Karl A. Hassan, I. Paulsen, U. H. Stroeher, 2013, Infection and Immunity.

Genome‐based evolutionary history of Pseudomonas spp

Karl A. Hassan, N. Kyrpides, N. Shapiro, 2018, Environmental microbiology.

Comparative genomics between human and animal associated subspecies of the Mycobacterium avium complex: a basis for pathogenicity

Karl A. Hassan, B. Neilan, H. Mitchell, 2015, BMC Genomics.

Physiological Functions of Bacterial "Multidrug" Efflux Pumps.

Karl A. Hassan, I. Paulsen, P. Henderson, 2021, Chemical reviews.

Genome Degradation in Brucella ovis Corresponds with Narrowing of Its Host Range and Tissue Tropism

Jeffrey R. Robinson, Karl A. Hassan, I. Paulsen, 2009, PloS one.

Genomic analyses of Clostridium perfringens isolates from five toxinotypes.

Karl A. Hassan, I. Paulsen, L. Elbourne, 2015, Research in microbiology.

Molecular evolution of VH9 germline genes isolated from DBA, BALB, 129 and C57BL mouse strains and sublines

Karl A. Hassan, A. Franklin, E. Steele, 2003, Immunogenetics.

Homologs of the Acinetobacter baumannii AceI Transporter Represent a New Family of Bacterial Multidrug Efflux Systems

Karl A. Hassan, I. Paulsen, P. Henderson, 2015, mBio.

The Rsm regulon of plant growth-promoting Pseudomonas fluorescens SS101: role of small RNAs in regulation of lipopeptide biosynthesis

Karl A. Hassan, I. Paulsen, Judith E. van de Mortel, 2014, Microbial biotechnology.

Characterizing the Mechanism of Action of an Ancient Antimicrobial, Manuka Honey, against Pseudomonas aeruginosa Using Modern Transcriptomics

Karl A. Hassan, I. Paulsen, C. Whitchurch, 2020, mSystems.

Characterising the mechanism of action of an ancient antimicrobial, honey, using modern transcriptomics

Karl A. Hassan, I. Paulsen, C. Whitchurch, 2020, bioRxiv.

Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4.

D. M. Ivey, Karl A. Hassan, A. Kolstø, 2011, Environmental microbiology.

The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump

Karl A. Hassan, I. Paulsen, Liping Li, 2021, Communications Biology.

Single-Step Selection of Drug Resistant Acinetobacter baylyi ADP1 Mutants Reveals a Functional Redundancy in the Recruitment of Multidrug Efflux Systems

Karl A. Hassan, I. Paulsen, Anthony J. Brzoska, 2013, PloS one.

The Impact of Omega-3 Fatty Acids on the Evolution of Acinetobacter baumannii Drug Resistance

Karl A. Hassan, B. Eijkelkamp, Felise G. Adams, 2021, Microbiology spectrum.

Identification of a Novel Ciprofloxacin Tolerance Gene, aciT, Which Contributes to Filamentation in Acinetobacter baumannii

Karl A. Hassan, I. Paulsen, M. Molloy, 2021, Antimicrobial Agents and Chemotherapy.

Investigation of the human pathogen Acinetobacter baumannii under iron limiting conditions

Karl A. Hassan, I. Paulsen, B. Eijkelkamp, 2011, BMC Genomics.

An ace up their sleeve: a transcriptomic approach exposes the AceI eﬄux protein of Acinetobacter baumannii and reveals the drug eﬄux potential hidden in many microbial pathogens

Karl A. Hassan, A. Kolstø, I. Paulsen, 2015, Front. Microbiol..

Genome Sequence of Vibrio rotiferianus Strain DAT722

Karl A. Hassan, I. Paulsen, Y. Boucher, 2011, Journal of bacteriology.

Identification of a novel LysR family transcriptional regulator controlling acquisition of sulfur sources in Acinetobacter baumannii.

Amy K. Cain, Karl A. Hassan, I. Paulsen, 2023, Microbial Physiology.

Effect of Tannic Acid on the Transcriptome of the Soil Bacterium Pseudomonas protegens Pf-5

Karl A. Hassan, Chee Kent Lim, I. Paulsen, 2013, Applied and Environmental Microbiology.

Inactivation of the GacA response regulator in Pseudomonas fluorescens Pf-5 has far-reaching transcriptomic consequences.

Karl A. Hassan, I. Paulsen, Q. Ren, 2010, Environmental microbiology.

Impact of DNA damaging agents on genome-wide transcriptional profiles in two marine Synechococcus species

Karl A. Hassan, Katherine H. Phillippy, I. Paulsen, 2013, Front. Microbiol..

Development of a High-Throughput Cloning Strategy for Characterization of Acinetobacter baumannii Drug Transporter Proteins

Karl A. Hassan, I. Paulsen, B. Eijkelkamp, 2011, Journal of Molecular Microbiology and Biotechnology.

Regulation of the aceI multidrug efflux pump gene in Acinetobacter baumannii

Karl A. Hassan, I. Paulsen, Liping Li, 2018, The Journal of antimicrobial chemotherapy.

Featuresbaumannii Virulence H-NS Plays a Role in Expression of

Karl A. Hassan, I. Paulsen, U. H. Stroeher, 2013 .

The Acinetobacter baumannii virulence factor Omp33 is important for tolerance to benzalkonium chloride

Karl A. Hassan, I. Paulsen, B. Shah, 2023, bioRxiv.

Comparative Genomics of Plant-Associated Pseudomonas spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions

Young Cheol Kim, Edward W. Davis, Karl A. Hassan, 2012, PLoS genetics.

Molecular evolution of VH9 germline genes isolated from DBA, BALB, 129 and C57BL mouse strains and sublines

Karl A. Hassan, A. Franklin, E. Steele, 2003, Immunogenetics.

Effect of Tannic Acid on the Transcriptome of the Soil Bacterium Pseudomonas protegens Pf-5

Karl A. Hassan, Chee Kent Lim, I. Paulsen, 2013, Applied and Environmental Microbiology.

Genome Sequence of the Neurotoxigenic Clostridium butyricum Strain 5521

Karl A. Hassan, I. Paulsen, Eric A. Johnson, 2014, Genome Announcements.

Genome Sequence of the Group III Clostridium botulinum Strain Eklund-C

Karl A. Hassan, I. Paulsen, Eric A. Johnson, 2013, Genome Announcements.