Pascal Poignard

发表

IDEPI: Rapid Prediction of HIV-1 Antibody Epitopes and Other Phenotypic Features from Sequence Data Using a Flexible Machine Learning Platform

Ben Murrell, Sergei L. Kosakovsky Pond, Konrad Scheffler, 2014, PLoS Comput. Biol..

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Baoshan Zhang, Peter D. Kwong, Michael S. Seaman, 2015, Nature.

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Ron Diskin, Beatrix Ueberheide, Michael S. Seaman, 2011, Science.

Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

Dennis R. Burton, Pascal Poignard, D. Burton, 2014, Scientific Reports.

Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

Ben Murrell, William R. Schief, Thomas Vollbrecht, 2019, Immunity.

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Yan Liu, William R. Schief, Ryan McBride, 2011, Science.

Highly Potent RANTES Analogues either Prevent CCR5-Using Human Immunodeficiency Virus Type 1 Infection In Vivo or Rapidly Select for CXCR4-Using Variants

Pascal Poignard, Donald E. Mosier, Jill Wilken, 1999, Journal of Virology.

Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120

Paul W. H. I. Parren, Dennis R. Burton, Pascal Poignard, 2003, Journal of Virology.

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.

Wayne C Koff, Chung-Yi Wu, Chi-Huey Wong, 2014, Immunity.

Broad neutralization coverage of HIV by multiple highly potent antibodies

Pham Phung, Terri Wrin, Chi-Huey Wong, 2011, Nature.

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Ryan McBride, Robyn L. Stanfield, Andrew B. Ward, 2013, PLoS pathogens.

Rapid Sequencing of Complete env Genes from Primary HIV-1 Samples.

Yan Guo, Ben Murrell, Pham Phung, 2016, Virus evolution.

A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

Dennis R. Burton, Pascal Poignard, D. Burton, 2010, PLoS pathogens.

Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

Pascal Poignard, Dennis R Burton, D. Burton, 2009, Nature Medicine.

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

Ben Murrell, Jianming Tang, Adam Godzik, 2016, PLoS pathogens.

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2016, Immunity.

Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1

Christoph Grundner, Christos J. Petropoulos, Terri Wrin, 2003, Journal of Virology.

Profiling human antibody responses by integrated single-cell analysis.

Douglas S Kwon, J Christopher Love, Navin Varadarajan, 2014, Vaccine.

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

Lynn Morris, Yan Liu, Michael S. Seaman, 2012, The Journal of experimental medicine.

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.

James C Paulson, Pascal Poignard, Ian A Wilson, 2014, Immunity.

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Pham Phung, Terri Wrin, Dennis R. Burton, 2009, Science.

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2017, Immunity.

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses.

Alessandro Sette, Mark M Davis, Mark M. Davis, 2013, Immunity.

Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV

William R. Schief, Michael S. Seaman, Dennis R. Burton, 2014, Science Translational Medicine.

Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm

Terri Wrin, Josephine Birungi, Dennis R. Burton, 2009, Journal of Virology.

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

Daphne Koller, George M. Church, Jonathan Laserson, 2013, PLoS pathogens.

Therapeutic Efficacy of Potent Neutralizing HIV-1-Specific Monoclonal Antibodies in SHIV-Infected Rhesus Monkeys

Michael S. Seaman, Florian Klein, Arup K. Chakraborty, 2013, Nature.

PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4

Tongqing Zhou, Terri Wrin, Peter D. Kwong, 2012, Journal of Virology.