Sandeep Kumar

发表

AggreRATE-Pred: a mathematical model for the prediction of change in aggregation rate upon point mutation

M Michael Gromiha, Puneet Rawat, R Prabakaran, 2019, Bioinform..

Computational approaches to therapeutic antibody design: established methods and emerging trends

Sebastian Kelm, Alexandre M J J Bonvin, Lucy J. Colwell, 2019, Briefings Bioinform..

Sandeep Kumar, Sandeep Kumar, S. Singh, 2012, Drug discovery today.

Consequences of glycan truncation on Fc structural integrity

Sandeep Kumar, Patrick M Buck, P. M. Buck, 2013, mAbs.

Thermodynamic and kinetic determinants of Thermotoga maritima cold shock protein stability: A structural and dynamic analysis

Chie Motono, M Michael Gromiha, Sandeep Kumar, 2008, Proteins.

Insights into the potential aggregation liabilities of the b12 Fab fragment via elevated temperature molecular dynamics.

Sandeep Kumar, Patrick M Buck, P. M. Buck, 2013, Protein engineering, design & selection : PEDS.

Relationship between potential aggregation-prone regions and HLA-DR-binding T-cell immune epitopes: implications for rational design of novel and follow-on therapeutic antibodies.

Sandeep Kumar, Sandeep Kumar, S. Singh, 2012, Journal of pharmaceutical sciences.

Highly viscous antibody solutions are a consequence of network formation caused by domain-domain electrostatic complementarities: insights from coarse-grained simulations.

Anuj Chaudhri, Sandeep Kumar, Patrick M Buck, 2015, Molecular pharmaceutics.

CPAD, Curated Protein Aggregation Database: A Repository of Manually Curated Experimental Data on Protein and Peptide Aggregation

A. Mary Thangakani, D. Velmurugan, Sandeep Kumar, 2016, PloS one.

Potential Aggregation-Prone Regions in Complementarity-Determining Regions of Antibodies and Their Contribution Towards Antigen Recognition: A Computational Analysis

Sandeep Kumar, Satish K. Singh, Sandeep Kumar, 2010, Pharmaceutical Research.

The Dual Role of Lipids of the Lipoproteins in Trumenba, a Self-Adjuvanting Vaccine Against Meningococcal Meningitis B Disease

Jason C. Rouse, Lakshmi Khandke, Sandeep Kumar, 2016, The AAPS Journal.

Concentration Dependent Viscosity of Monoclonal Antibody Solutions: Explaining Experimental Behavior in Terms of Molecular Properties

Li Li, Patrick M. Buck, Sandeep Kumar, 2014, Pharmaceutical Research.

In Silico Prediction of Diffusion Interaction Parameter (kD), a Key Indicator of Antibody Solution Behaviors

Li Li, Sandeep Kumar, Matthew P. Broulidakis, 2018, Pharmaceutical Research.

How do thermophilic proteins resist aggregation?

Devadasan Velmurugan, Anthony Mary Thangakani, Sandeep Kumar, 2012, Proteins.

Potential aggregation prone regions in biotherapeutics

Sandeep Kumar, Sandeep Kumar, S. Singh, 2009, mAbs.

Metal ion leachates and the physico-chemical stability of biotherapeutic drug products.

Sandeep Kumar, Sandeep Kumar, S. Singh, 2014, Current pharmaceutical design.

Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development

Li Li, Sumit Goswami, Sandeep Kumar, 2016, mAbs.

Computational methods to predict therapeutic protein aggregation.

Bernhardt L Trout, Sandeep Kumar, Neeraj J Agrawal, 2012, Methods in molecular biology.

In-silico prediction of concentration-dependent viscosity curves for monoclonal antibody solutions

Li Li, Sandeep Kumar, Matthew P. Broulidakis, 2017, mAbs.

Autoimmune Responses to Soluble Aggregates of Amyloidogenic Proteins Involved in Neurodegenerative Diseases: Overlapping Aggregation Prone and Autoimmunogenic regions

Sandeep Kumar, D Velmurugan, D. Velmurugan, 2016, Scientific Reports.

Identification and Impact of Aggregation‐Prone Regions in Proteins and Therapeutic Monoclonal Antibodies

Sandeep Kumar, Satish K. Singh, Sandeep Kumar, 2010 .

Trimerization Dictates Solution Opalescence of a Monoclonal Antibody.

Wei Wang, Sandeep Kumar, Sandeep Kumar, 2016, Journal of pharmaceutical sciences.

Rational design of viscosity reducing mutants of a monoclonal antibody: Hydrophobic versus electrostatic inter-molecular interactions

Li Li, Sumit Goswami, Sandeep Kumar, 2015, mAbs.

Assessment of Physical Stability of an Antibody Drug Conjugate by Higher Order Structure Analysis: Impact of Thiol- Maleimide Chemistry

Sandeep Kumar, Jianxin Guo, Satish K. Singh, 2014, Pharmaceutical Research.

Aggregation prone regions in human proteome: Insights from large‐scale data analyses

Dhruv Goel, Sandeep Kumar, R Prabakaran, 2017, Proteins.

Coupling of Aggregation and Immunogenicity in Biotherapeutics: T- and B-Cell Immune Epitopes May Contain Aggregation-Prone Regions

Sandeep Kumar, Satish K. Singh, Sandeep Kumar, 2011, Pharmaceutical Research.

Aggregation in protein-based biotherapeutics: computational studies and tools to identify aggregation-prone regions.

Bernhardt L Trout, Sandeep Kumar, Neeraj J Agrawal, 2011, Journal of pharmaceutical sciences.