Huda Y. Zoghbi

发表

Beta-Binomial Modeling of CRISPR Pooled Screen Data Identifies Target Genes with Greater Sensitivity and fewer False Negatives

Zhandong Liu, Hyun-Hwan Jeong, Seon Young Kim, 2019, BCB.

Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10

Takanori Yamagata, Huda Y. Zoghbi, Caleb F. Davis, 2000, Nature Genetics.

The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless Proteins

Juan Botas, Hugo J. Bellen, Huda Y. Zoghbi, 2005, Cell.

Merkel Cells Are Essential for Light-Touch Responses

Gregory J. Gerling, Ellen A. Lumpkin, G. J. Gerling, 2009, Science.

Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome

Christina Thaller, Huda Y. Zoghbi, C. Thaller, 2006, Proceedings of the National Academy of Sciences.

Diseases of Unstable Repeat Expansion: Mechanisms and Common Principles

Huda Y. Zoghbi, H. Zoghbi, J. Gatchel, 2005, Nature Reviews Genetics.

Serine 776 of Ataxin-1 Is Critical for Polyglutamine-Induced Disease in SCA1 Transgenic Mice

Effat S. Emamian, Huda Y. Zoghbi, Harry T. Orr, 2003, Neuron.

Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells

Stephen T. C. Wong, Huda Y. Zoghbi, Xiaobo Zhou, 2022 .

CHIP Protects from the Neurotoxicity of Expanded and Wild-type Ataxin-1 and Promotes Their Ubiquitination and Degradation*

Ismael Al-Ramahi, Juan Botas, Huda Y. Zoghbi, 2006, Journal of Biological Chemistry.

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the α1A-voltage-dependent calcium channel

William B. Dobyns, Huda Y. Zoghbi, Tetsuo Ashizawa, 1997, Nature Genetics.

MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome

Wei Li, Huda Y. Zoghbi, Chad A. Shaw, 2015, Proceedings of the National Academy of Sciences.

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1

Huda Y. Zoghbi, Arthur L. Beaudet, Harry T. Orr, 1993, Nature Genetics.

Increased Expression of α1A Ca2+Channel Currents Arising from Expanded Trinucleotide Repeats in Spinocerebellar Ataxia Type 6

Huda Y. Zoghbi, Olga Zhuchenko, R. Tsien, 2001, The Journal of Neuroscience.

SCA1-like Disease in Mice Expressing Wild-Type Ataxin-1 with a Serine to Aspartic Acid Replacement at Residue 776

Huda Y. Zoghbi, Harry T. Orr, Janghoo Lim, 2010, Neuron.

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1

Michael A. Mancini, Huda Y. Zoghbi, Harry T. Orr, 1998, Nature Genetics.

Calcium Dynamics and Electrophysiological Properties of Cerebellar Purkinje Cells in SCA1 Transgenic Mice

William N. Ross, Takafumi Inoue, Huda Y. Zoghbi, 2001 .

Genetic regulation of cerebellar development

Huda Y. Zoghbi, H. Zoghbi, Vincent Y. Wang, 2001, Nature Reviews Neuroscience.

Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1

Huda Y. Zoghbi, Harry T. Orr, H. Zoghbi, 2000, Nature Neuroscience.

Amino acids in a region of ataxin-1 outside of the polyglutamine tract influence the course of disease in SCA1 transgenic mice

Huda Y. Zoghbi, Harry T. Orr, H. Zoghbi, 2002, NeuroMolecular Medicine.