Graeme Milligan

发表

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

George Khelashvili, Kevin C. Dorff, Jufang Shan, 2010, Bioinform..

The First 50 Years of Molecular Pharmacology

Graeme Milligan, Joan Heller Brown, William A Catterall, 2015, Molecular Pharmacology.

Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base

Michel Bouvier, Susan R. George, Jonathan A. Javitch, 2007, BMC Bioinformatics.

Reconfigurable hardware for control applications

Graeme Milligan, 2008 .

Functional coupling of receptor G-protein fusions to the cloned G-protein-gated K+ channel

Graeme Milligan, Andrew Tinker, Joanne L. Leaney, 2001 .

High-content assays for ligand regulation of G-protein-coupled receptors.

Graeme Milligan, G. Milligan, 2003, Drug discovery today.

G protein-coupled receptors : structure, signaling, and physiology

Graeme Milligan, G. Milligan, Sandra Siehler, 2010 .

Techniques: promiscuous Galpha proteins in basic research and drug discovery.

Graeme Milligan, Evi Kostenis, Magali Waelbroeck, 2005, Trends in pharmacological sciences.

Agonist occupancy of a single monomeric element is sufficient to cause internalization of the dimeric beta2-adrenoceptor.

Graeme Milligan, G. Milligan, J. Pediani, 2007, Cellular signalling.

Techniques: promiscuous Galpha proteins in basic research and drug discovery.

Graeme Milligan, Evi Kostenis, G. Milligan, 2005, Trends in pharmacological sciences.

The specificity and molecular basis of α1-adrenoceptor and CXCR chemokine receptor dimerization

Graeme Milligan, G. Milligan, Shirley Wilson, 2007, Journal of Molecular Neuroscience.

G protein‐coupled receptor hetero‐dimerization: contribution to pharmacology and function

Graeme Milligan, G. Milligan, 2009, British journal of pharmacology.

The other side of opioid receptor signalling: regulation by protein-protein interaction.

Graeme Milligan, G. Milligan, Z. Georgoussi, 2012, Current drug targets.

The CXCR1 and CXCR2 Receptors Form Constitutive Homo- and Heterodimers Selectively and with Equal Apparent Affinities*

Graeme Milligan, G. Milligan, Shirley Wilson, 2005, Journal of Biological Chemistry.

The role of dimerisation in the cellular trafficking of G-protein-coupled receptors.

Graeme Milligan, G. Milligan, 2010, Current opinion in pharmacology.

High-Throughput Identification and Characterization of Novel, Species-selective GPR35 Agonists

Graeme Milligan, G. Milligan, A. Mackenzie, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Homo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between less closely related sequences.

Graeme Milligan, S. Rees, G. Milligan, 2002, The Biochemical journal.

The chemokine receptor CCX‐CKR mediates effective scavenging of CCL19 in vitro

Graeme Milligan, G. Milligan, S. Milasta, 2006, European journal of immunology.

Identification of a serotonin/glutamate receptor complex implicated in psychosis

Graeme Milligan, Marta Filizola, Tony Yuen, 2008, Nature.

G protein-coupled receptor dimerisation: molecular basis and relevance to function.

Graeme Milligan, G. Milligan, 2007, Biochimica et biophysica acta.

International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers

Michel Bouvier, Lakshmi Devi, Jonathan A. Javitch, 2007, Pharmacological Reviews.

The α1b-Adrenoceptor Exists as a Higher-Order Oligomer: Effective Oligomerization Is Required for Receptor Maturation, Surface Delivery, and Function

Graeme Milligan, Meritxell Canals, G. Milligan, 2007, Molecular Pharmacology.

Constitutive Activity of the Cannabinoid CB1 Receptor Regulates the Function of Co-expressed Mu Opioid Receptors*

Graeme Milligan, Meritxell Canals, G. Milligan, 2008, Journal of Biological Chemistry.

Applications of bioluminescence- and fluorescence resonance energy transfer to drug discovery at G protein-coupled receptors.

Graeme Milligan, G. Milligan, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor*

Graeme Milligan, Trond Ulven, Irina G. Tikhonova, 2013, The Journal of Biological Chemistry.

Methods to monitor the quaternary structure of G protein‐coupled receptors

Michel Bouvier, Graeme Milligan, G. Milligan, 2005, The FEBS journal.

Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes

Graeme Milligan, G. Milligan, N. J. Smith, 2010, Pharmacological Reviews.

Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

Graeme Milligan, Francisco Ciruela, Meritxell Canals, 2006, The Journal of Neuroscience.

G Protein-Coupled Receptor Dimerization: Function and Ligand Pharmacology

Graeme Milligan, G. Milligan, 2004, Molecular Pharmacology.

Domain Swapping in the Human Histamine H1 Receptor

Graeme Milligan, Rob Leurs, R. Leurs, 2004, Journal of Pharmacology and Experimental Therapeutics.

Building a new conceptual framework for receptor heteromers.

Michel Bouvier, Graeme Milligan, Jonathan A Javitch, 2009, Nature chemical biology.

G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

Martin J. Lohse, Graeme Milligan, Marta Filizola, 2014, Pharmacological Reviews.

G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery.

Graeme Milligan, G. Milligan, 2006, Drug discovery today.

Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells.

Graeme Milligan, Andrew H Baker, Joanne C Mountford, 2010, Biochemical Society transactions.

Dimers of Class A G Protein-coupled Receptors Function via Agonist-mediated Trans-activation of Associated G Proteins*

Graeme Milligan, G. Milligan, J. Pediani, 2003, Journal of Biological Chemistry.

G Protein Coupling and Ligand Selectivity of the D2L and D3 Dopamine Receptors

Graeme Milligan, Alan Wise, S. Rees, 2008, Journal of Pharmacology and Experimental Therapeutics.

G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets

Graeme Milligan, Trond Ulven, B. Hudson, 2014, British Journal of Nutrition.