Irene M. Kaplow

发表

A Classifier-based approach to identify genetic similarities between diseases

Atul J. Butte, Serafim Batzoglou, Marc A. Schaub, 2009, Bioinform..

RNAiCut: automated detection of significant genes from functional genomic screens

Bonnie Berger, Norbert Perrimon, Irene M. Kaplow, 2009, Nature Methods.

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

Eran Segal, David van Dijk, Irene M. Kaplow, 2013, Genome research.

Predicting lineage-specific differences in open chromatin across dozens of mammalian genomes 2 3

Andreas R. Pfenning, Irene M. Kaplow, Morgan E. Wirthlin, 2020 .

Addiction-Associated Genetic Variants Implicate Brain Cell Type- and Region-Specific Cis-Regulatory Elements in Addiction Neurobiology

Andreas R. Pfenning, BaDoi N. Phan, Irene M. Kaplow, 2020, The Journal of Neuroscience.

The Regulatory Evolution of the Primate Fine-Motor System

Andreas R. Pfenning, William R. Stauffer, BaDoi N. Phan, 2020, bioRxiv.

A pooling-based approach to mapping genetic variants associated with DNA methylation

Irene M. Kaplow, H. Fraser, M. Kobor, 2015, bioRxiv.

Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements

Michael Wainberg, Anshul Kundaje, Oana Ursu, 2019, bioRxiv.

Fine-mapping cis-regulatory variants in diverse human populations

Peter A. Combs, Irene M. Kaplow, Hunter B. Fraser, 2018, bioRxiv.

Fine-mapping cis-regulatory variants in diverse human populations

Irene M. Kaplow, H. Fraser, B. Hie, 2018, bioRxiv.

Machine learning sequence prioritization for cell type-specific enhancer design.

Andreas R. Pfenning, BaDoi N. Phan, Irene M. Kaplow, 2022, eLife.

Relating enhancer genetic variation across mammals to complex phenotypes using machine learning

Andreas R. Pfenning, BaDoi N. Phan, Irene M. Kaplow, 2022, bioRxiv.

An in vivo massively parallel platform for deciphering tissue-specific regulatory function

Andreas R. Pfenning, BaDoi N. Phan, Irene M. Kaplow, 2022, bioRxiv.

Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer’s disease

Andreas R. Pfenning, BaDoi N. Phan, Irene M. Kaplow, 2022, bioRxiv.

Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements

Andreas R. Pfenning, Julie E. Elie, Irene M. Kaplow, 2022, bioRxiv.

Neural network modeling of differential binding between wild-type and mutant CTCF reveals putative binding preferences for zinc fingers 1–2

Irene M. Kaplow, Chuan-Sheng Foo, A. Banerjee, 2021, BMC Genomics.

A pooling-based approach to mapping genetic variants associated with DNA methylation

Irene M. Kaplow, H. Fraser, M. Kobor, 2015, bioRxiv.

Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin

Andreas R. Pfenning, Irene M. Kaplow, Morgan E. Wirthlin, 2020, bioRxiv.

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements

Michael P Snyder, Michael Wainberg, Anshul Kundaje, 2019, Nature Communications.

Machine learning sequence prioritization for cell type-specific enhancer design

Andreas R. Pfenning, Irene M. Kaplow, Morgan E. Wirthlin, 2021, bioRxiv.

Neural network modeling of differential binding between wild-type and mutant CTCF reveals putative binding preferences for zinc fingers 1–2

Irene M. Kaplow, Chuan-Sheng Foo, A. Banerjee, 2022, BMC genomics.

Evolutionary constraint and innovation across hundreds of placental mammals

Voichita D. Marinescu, Andreas R. Pfenning, Graham M. Hughes, 2023, bioRxiv.

opposing effects on promoter dynamics and transcriptional noise Two DNA-encoded strategies for increasing expression with Material Supplemental

Irene M. Kaplow, E. Segal, A. Weinberger, 2013 .

Population-specific neuromodulation prolongs therapeutic benefits of deep brain stimulation

Andreas R. Pfenning, Irene M. Kaplow, A. Gittis, 2021, Science.

The functional and evolutionary impacts of human-specific deletions in conserved elements

Voichita D. Marinescu, Andreas R. Pfenning, Graham M. Hughes, 2023, Science.

The contribution of historical processes to contemporary extinction risk in placental mammals

Voichita D. Marinescu, Andreas R. Pfenning, Graham M. Hughes, 2023, Science.

Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs

Voichita D. Marinescu, Gavin J. Svenson, Andreas R. Pfenning, 2023, Science.

Insights into mammalian TE diversity through the curation of 248 genome assemblies

Voichita D. Marinescu, Andreas R. Pfenning, Matthew G. Johnson, 2023, Science.

Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease

Voichita D. Marinescu, Andreas R. Pfenning, Graham M. Hughes, 2023, bioRxiv.

Mammalian evolution of human cis-regulatory elements and transcription factor binding sites

Voichita D. Marinescu, Andreas R. Pfenning, Graham M. Hughes, 2023, Science.

CS 229 Project : A Machine Learning Framework for Biochemical Reaction Matching

Irene M. Kaplow, Tomer Altman, Ryan Thompson, 2010 .

Insights into mammalian TE diversity through the curation of 248 genome assemblies

Voichita D. Marinescu, Andreas R. Pfenning, Matthew G. Johnson, 2023, Science.

Evolutionary constraint and innovation across hundreds of placental mammals

Voichita D. Marinescu, Andreas R. Pfenning, BaDoi N. Phan, 2023, Science.

HALPER facilitates the identification of regulatory element orthologs across species

Morgan Wirthlin, Andreas R. Pfenning, Irene M. Kaplow, 2020, Bioinform..

Relating enhancer genetic variation across mammals to complex phenotypes using machine learning

Andreas R. Pfenning, BaDoi N. Phan, Irene M. Kaplow, 2023, Science.

Vocal learning–associated convergent evolution in mammalian proteins and regulatory elements

Voichita D. Marinescu, Andreas R. Pfenning, BaDoi N. Phan, 2024, Science.

Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin

Andreas R. Pfenning, Irene M. Kaplow, Morgan E. Wirthlin, 2022, BMC Genomics.