Philip Seeman

发表

Structural Investigation of the Dopamine-2 Receptor Agonist Bromocriptine Binding to Dimeric D2HighR and D2LowR States

Serdar Durdagi, Ramin Ekhteiari Salmas, Matthias Stein, 2018, J. Chem. Inf. Model..

Philip Seeman, 2007, Scholarpedia.

Philip Seeman, Robert Fortuine, Mary Szwarc, 1959 .

Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography.

Sylvain Houle, Alan A. Wilson, Shitij Kapur, 2005, Journal of medicinal chemistry.

Rats with persistently high exploratory activity have both higher extracellular dopamine levels and higher proportion of D 2High receptors in the striatum

Jaanus Harro, Philip Seeman, P. Seeman, 2009, Synapse.

The Creation of Psychopharmacology

Philip Seeman, P. Seeman, 2002, Nature Medicine.

Increased dopamine D2High receptors in amphetamine‐sensitized rats, measured by the agonist [3H](+)PHNO

Shitij Kapur, Philip Seeman, S. Kapur, 2007, Synapse.

Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo.

Alan A. Wilson, Shitij Kapur, Philip Seeman, 2008, Nuclear medicine and biology.

Binding characteristics and sensitivity to endogenous dopamine of [11C]‐(+)‐PHNO, a new agonist radiotracer for imaging the high‐affinity state of D2 receptors in vivo using positron emission tomography

Sylvain Houle, Laurent Galineau, Alan A. Wilson, 2006, Journal of neurochemistry.

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

Philip Seeman, Roger K. Sunahara, R. Sunahara, 1991, Nature.

Opening the dopomine D4 door: A commentary on the paper

Philip Seeman, Tokio Yamaguchi, Hubert H. M. Van Tol, 1996 .

The Dopamine D1 Receptors

Philip Seeman, Mark R. Brann, P. Seeman, 1992 .

Increased dopamine D2(High) receptors in amphetamine-sensitized rats, measured by the agonist [(3)H](+)PHNO.

Shitij Kapur, Philip Seeman, S. Kapur, 2007, Synapse.

Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis.

Philip Seeman, R. Palmiter, D. Grandy, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Human brain dopamine receptors in children and aging adults

Philip Seeman, Peter Riederer, Kurt Jellinger, 1987, Synapse.

High-Affinity States of Human Brain Dopamine D2/3 Receptors Imaged by the Agonist [11C]-(+)-PHNO

Sylvain Houle, Alan A. Wilson, Shitij Kapur, 2006, Biological Psychiatry.

Schizophrenia hippocampus has elevated expression of chondrex glycoprotein gene

Philip Seeman, P. Seeman, Teresa Tallerico, 2003, Synapse.

Brain region binding of the D2/3 agonist [11C]‐(+)‐PHNO and the D2/3 antagonist [11C]raclopride in healthy humans

Ariel Graff-Guerrero, Alan A. Wilson, Shitij Kapur, 2008, Human brain mapping.

Dopamine D2 receptor density remains constant in treated Parkinson's disease

Philip Seeman, Mark Guttman, Peter Riederer, 1986, Annals of neurology.

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

Susan R. George, Philip Seeman, Roger K. Sunahara, 1991, Nature.

Atypical Antipsychotics: Mechanism of Action

Philip Seeman, P. Seeman, 2002, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

Psychosis pathways converge via D2High dopamine receptors

Johannes Schwarz, Kazuhiko Yanai, Tomiki Sumiyoshi, 2006, Synapse.

Methylphenidate elevates resting dopamine which lowers the impulse-triggered release of dopamine: a hypothesis

Philip Seeman, P. Seeman, B. Madras, 2002, Behavioural Brain Research.

Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus

Peter Gmeiner, Alan A. Wilson, Shitij Kapur, 2006, Synapse.

Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine

Philip Seeman, D. Wong, F. Bymaster, 1996, Neuropsychopharmacology.

Anesthetics inhibit high‐affinity states of dopamine D2 and other G‐linked receptors

Shitij Kapur, Philip Seeman, S. Kapur, 2003, Synapse.