Yasuhiro Tsume

Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro‐in silico‐in vivo approach

Marival Bermejo, Bart Hens, Gregory E. Amidon, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP

Kerby Shedden, Marival Bermejo, Bart Hens, 2020, Pharmaceutics.

Oral product input to the GI tract: GIS an oral product performance technology

Yasuhiro Tsume, Gordon L. Amidon, G. Amidon, 2017, Frontiers of Chemical Science and Engineering.

Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded '21st Century BA/BE' project.

James G Brasseur, Kerby Shedden, Niloufar Salehi, 2018, International journal of pharmaceutics.

In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents.

Kazuki Matsui, Yasuhiro Tsume, G. Amidon, 2015, Molecular pharmaceutics.

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.

Kerby Shedden, Jianghong Fan, Marival Bermejo, 2017, Molecular pharmaceutics.

Evaluation of a three compartment in vitro gastrointestinal simulator dissolution apparatus to predict in vivo dissolution.

Yasuhiro Tsume, Gordon L Amidon, G. Amidon, 2014, Journal of pharmaceutical sciences.

The biowaiver extension for BCS class III drugs: the effect of dissolution rate on the bioequivalence of BCS class III immediate-release drugs predicted by computer simulation.

Yasuhiro Tsume, Gordon L. Amidon, G. Amidon, 2010, Molecular pharmaceutics.

Bile acid-oligopeptide conjugates interact with DNA and facilitate transfection.

Yasuhiro Tsume, John M Hilfinger, Blake J Roessler, 2007, Molecular pharmaceutics.

Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time

Bo Wen, Yasuhiro Tsume, Gordon L. Amidon, 2017, The AAPS Journal.

The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS)

Kazuki Matsui, Yasuhiro Tsume, Gordon L Amidon, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.