Justin Guinney

发表

Abstract B051: Facilitating translational research with interactive tools for immuno-oncology data

Vesteinn Thorsson, James A. Eddy, Andrew Lamb, 2019 .

Alternative models for sharing confidential biomedical data

Justin Guinney, Julio Saez-Rodriguez, J. Saez-Rodriguez, 2018, Nature Biotechnology.

The Geometry of Cancer

Justin Guinney, J. Guinney, 2009 .

rCGH: a comprehensive array-based genomic profile platform for precision medicine

Justin Guinney, Brian M. Bot, Frederic Commo, 2015, Bioinform..

Infrastructure for coordinating multi-site clinical research projects via REDCap and Synapse

Justin Guinney, Xindi Guo, Kristen K. Dang, 2018 .

Modeling Cancer Progression via Pathway Dependencies

Sayan Mukherjee, Justin Guinney, Elena J. Edelman, 2008, PLoS Comput. Biol..

Learning Gradients: Predictive Models that Infer Geometry and Statistical Dependence

Sayan Mukherjee, Justin Guinney, Mauro Maggioni, 2010, J. Mach. Learn. Res..

2018 AACR Drug Target Explorer

Justin Guinney, Salvatore La Rosa, Annette Bakker, 2018 .

Correlation set analysis: detecting active regulators in disease populations using prior causal knowledge

Chia-Ling Huang, Charles DeLisi, Justin Guinney, 2012, BMC Bioinformatics.

Estimating variable structure and dependence in multitask learning via gradients

Sayan Mukherjee, Justin Guinney, Qiang Wu, 2011, Machine Learning.

GSVA: The Gene Set Variation Analysis package for microarray and RNA-seq data

Justin Guinney, Robert Castelo, H Sonja, 2016 .

The NIH BD2K center for big data in translational genomics

Lior Pachter, David Haussler, David A. Patterson, 2015, J. Am. Medical Informatics Assoc..

Abstract 4643: Drug-Target Explorer: An interactive tool for examining chemical-biological interactions

Justin Guinney, Salvatore La Rosa, Annette Bakker, 2018 .

Probing the chemical–biological relationship space with the Drug Target Explorer

Justin Guinney, Salvatore La Rosa, Sara J. C. Gosline, 2018, bioRxiv.

Stepwise Group Sparse Regression (SGSR): Gene-Set-Based Pharmacogenomic Predictive Models with Stepwise Selection of Functional Priors

Rodrigo Dienstmann, Justin Guinney, Adam A. Margolin, 2014, Pacific Symposium on Biocomputing.

Systematic Assessment of Analytical Methods for Drug Sensitivity Prediction from Cancer Cell Line Data

Justin Guinney, Elias Chaibub Neto, Adam A. Margolin, 2013, Pacific Symposium on Biocomputing.

Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles

Sayan Mukherjee, Justin Guinney, Andrea Bild, 2006, ISMB.

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Amir K. Foroushani, Yuanfang Guan, Jaewoo Kang, 2019, Nature Communications.

GSVA: gene set variation analysis for microarray and RNA-Seq data

Justin Guinney, Robert Castelo, Sonja Hänzelmann, 2013, BMC Bioinformatics.

F-Seq: a feature density estimator for high-throughput sequence tags

Terrence S. Furey, Justin Guinney, Alan P. Boyle, 2008, Bioinform..

Probing the chemical-biological relationship space with the Drug Target Explorer

Justin Guinney, Salvatore La Rosa, Sara J. C. Gosline, 2018, bioRxiv.

Combining accurate tumour genome simulation with crowd-sourcing to benchmark somatic variant detection

Takafumi Yamaguchi, Justin Guinney, Paul C. Boutros, 2015 .

Abstract 1690: A tumor deconvolution DREAM Challenge: Inferring immune infiltration from bulk gene expression data

Thomas Yu, Justin Guinney, Aaron M. Newman, 2019 .

Personalized Hypothesis Tests for Detecting Medication Response in Parkinson Disease Patients Using iPhone Sensor Data

Arno Klein, Justin Guinney, Larsson Omberg, 2016, PSB.

A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data

Julio Saez-Rodriguez, Wenyu Wang, Justin Guinney, 2021 .

Crowdsourced mapping of unexplored target space of kinase inhibitors

Avner Schlessinger, Krister Wennerberg, Tero Aittokallio, 2021, Nature communications.

NF Research Tools Database: An experimental resource database for the neurofibromatosis community

James A. Eddy, Justin Guinney, Caroline Morin, 2021 .

Preview of "Interpretable systems biomarkers predict response to immune-checkpoint inhibitors"

Justin Guinney, J. Guinney, 2021, Patterns.

Three years later: the NF Data Portal in 2021

Justin Guinney, Robert J. Allaway, Kaitlin Throgmorton, 2021 .

Data and codes behind "Crowdsourced mapping of unexplored target space of kinase inhibitors"

Avner Schlessinger, Tudor I. Oprea, Anna Cichonska, 2021 .

Evaluation of Combined Artificial Intelligence and Radiologist Assessment to Interpret Screening Mammograms

Berkman Sahiner, Jaime S. Cardoso, Thomas Yu, 2020, JAMA network open.

A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma.

Justin Guinney, J. Guinney, D. Harpole, 2011, The Annals of thoracic surgery.

Modeling RAS Phenotype in Colorectal Cancer Uncovers Novel Molecular Traits of RAS Dependency and Improves Prediction of Response to Targeted Agents in Patients

Justin Guinney, Claus Bendtsen, Charles Ferté, 2013, Clinical Cancer Research.

BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression

Sabine Tejpar, Stephen McLaughlin, Justin Guinney, 2016, Clinical Cancer Research.

Multi-targeting Drug Community Challenge.

Avner Schlessinger, Ruben Abagyan, Justin Guinney, 2017, Cell chemical biology.

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells

Rodrigo Dienstmann, Justin Guinney, Julio Saez-Rodriguez, 2016, bioRxiv.

Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

Justin Guinney, Hongyue Dai, Eric E. Schadt, 2011, PloS one.

Reducing overfitting in challenge-based competitions

Thomas Yu, Pablo Meyer, Justin Guinney, 2016, 1607.00091.

Reproducible biomedical benchmarking in the cloud: lessons from crowd-sourced data challenges

Thomas Yu, Justin Guinney, Julio Saez-Rodriguez, 2019, Genome Biology.

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

Ken Chen, David Haussler, Justin Guinney, 2018, bioRxiv.

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

David Haussler, Justin Guinney, Zechen Chong, 2018, bioRxiv.

Abstract 4725: Multiple Myeloma DREAM Challenge: A crowd-sourced challenge to improve identification of high-risk patients

Thomas Yu, Fadi Towfic, Justin Guinney, 2017 .

Impact of Bioinformatic Procedures in the Development and Translation of High-Throughput Molecular Classifiers in Oncology

Justin Guinney, Frederic Commo, Charles Ferté, 2013, Clinical Cancer Research.

Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data.

Thomas Yu, Tapio Pahikkala, Antti Airola, 2017, The Lancet. Oncology.