Ian A Wilson

发表

Outcome of a workshop on applications of protein models in biomedical research.

Roland L Dunbrack, Roland L. Dunbrack, Andrej Sali, 2009, Structure.

Massively parallel de novo protein design for targeted therapeutics

Lu Zhang, Xuhui Huang, David Baker, 2017, Nature.

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

Adam Godzik, Chittibabu Guda, Peter G Schultz, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif.

Ian A Wilson, A. Rudensky, I. Wilson, 2003, Journal of molecular biology.

Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2005, Proteins.

Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2002, Proteins.

The specificity of TCR/pMHC interaction.

Ian A Wilson, I. Wilson, M. Rudolph, 2002, Current opinion in immunology.

Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics.

Rebecca Page, Ian A Wilson, Raymond C Stevens, 2004, Journal of molecular biology.

Computational design of trimeric influenza neutralizing proteins targeting the hemagglutinin receptor binding site

David Baker, William Sheffler, Paul Yager, 2017, Nature Biotechnology.

Recognition of sialylated poly-N-acetyllactosamine chains on N- and O-linked glycans by human and avian influenza A virus hemagglutinins.

Ryan McBride, James C Paulson, Ian A Wilson, 2012, Angewandte Chemie.

The challenge of protein structure determination—lessons from structural genomics

Leszek Rychlewski, Adam Godzik, Ana P. C. Rodrigues, 2007, Protein science : a publication of the Protein Society.

Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.

Vasso Apostolopoulos, Ian A Wilson, Magdalena Plebanski, 2002, Journal of molecular biology.

Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.

Chi-Huey Wong, Ian A Wilson, I. Wilson, 2003, Bioorganic & medicinal chemistry.

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.

Chi-Huey Wong, James C Paulson, Ian A Wilson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

Weston B Struwe, Louise Royle, Ian A Wilson, 2016, Cell reports.

An αß T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science. 1996. 274: 209-219.

Robyn L Stanfield, Ian A Wilson, K Christopher Garcia, 2010, Journal of immunology.

Contrasting IgG structures reveal extreme asymmetry and flexibility.

Robyn L Stanfield, Pauline M Rudd, Erica Ollmann Saphire, 2002, Journal of molecular biology.

How TCRs bind MHCs, peptides, and coreceptors.

Robyn L Stanfield, Ian A Wilson, I. Wilson, 2006, Annual review of immunology.

Crystal structure of a PIN (PilT N‐terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2004, Proteins.

Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima

Ines Thiele, Adam Godzik, Ashley M Deacon, 2009, Science.

Crystal structures of apo wild‐type M. jannaschii tyrosyl‐tRNA synthetase (TyrRS) and an engineered TyrRS specific for O‐methyl‐L‐tyrosine

Lei Wang, Peter G Schultz, Yan Zhang, 2005, Protein science : a publication of the Protein Society.

Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.

Jamie K. Scott, Erica Ollmann Saphire, Ian A Wilson, 2007, Journal of molecular biology.

Three mutations switch H7N9 influenza to human-type receptor specificity

Ryan McBride, Robert J Woods, Xueyong Zhu, 2017, PLoS pathogens.

Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 Å resolution

Adam Godzik, Henry van den Bedem, Joanna Hale, 2005, Proteins.

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Robyn L Stanfield, Ian A Wilson, B. Korber, 2004, Journal of Virology.

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.

Wayne C Koff, Chung-Yi Wu, Chi-Huey Wong, 2014, Immunity.

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

Feng Wang, Peter G Schultz, Xueyong Zhu, 2013, Proceedings of the National Academy of Sciences.

Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.

John A Tainer, Adam Godzik, Henry van den Bedem, 2010, Journal of molecular biology.

XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators.

Adam Godzik, Ian A Wilson, Barbara J Meyer, 2003, Genes & development.

The Phosphatidylinositol 3-Kinase/Akt Cassette Regulates Purine Nucleotide Synthesis*

Wei Wang, Ian A Wilson, Gerry R Boss, 2009, Journal of Biological Chemistry.

Kinetic stabilization of an oligomeric protein by a single ligand binding event.

Steven M. Johnson, Ian A Wilson, I. Wilson, 2005, Journal of the American Chemical Society.

A Blueprint for HIV Vaccine Discovery.

Adam Godzik, Hendrik Streeck, M Juliana McElrath, 2012, Cell host & microbe.

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.

Ian A Wilson, Dennis R Burton, John P. Moore, 2015, Cell reports.

Specific recognition of a DNA immunogen by its elicited antibody.

Robyn L Stanfield, Ian A Wilson, Fernando A Goldbaum, 2007, Journal of molecular biology.

Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.

Chi-Huey Wong, Ian A Wilson, I. Wilson, 2009, Journal of molecular biology.

Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid.

Stephen J Benkovic, Yan Zhang, Ali Tavassoli, 2003, Biochemistry.

Structure and Function of the DUF2233 Domain in Bacteria and in the Human Mannose 6-Phosphate Uncovering Enzyme*

Adam Godzik, Hsiu-Ju Chiu, Ashley M Deacon, 2013, The Journal of Biological Chemistry.

Antibody vs. HIV in a clash of evolutionary titans.

Robyn L Stanfield, Ian A Wilson, Dennis R Burton, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.

Ian A Wilson, Todd O Yeates, V. Oseroff, 2003, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of a metal‐dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity

Adam Godzik, Mary Jo Ondrechen, Hsiu-Ju Chiu, 2011, Proteins.

Structural and thermodynamic correlates of T cell signaling.

Ian A Wilson, I. Wilson, J. Luz, 2002, Annual review of biophysics and biomolecular structure.

The HIV‐1 envelope glycoprotein structure: nailing down a moving target

Ian A Wilson, I. Wilson, A. Ward, 2017, Immunological reviews.

Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.

Jens Meiler, James E Crowe, David C Montefiori, 2015, The Journal of clinical investigation.

Crystal Structures of Human Bifunctional Enzyme Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/IMP Cyclohydrolase in Complex with Potent Sulfonyl-containing Antifolates*

Dennis W Wolan, Ian A Wilson, I. Wilson, 2004, Journal of Biological Chemistry.

Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity.

Ryan McBride, Robert J Woods, Oliver C Grant, 2017, Cell host & microbe.

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41.

Renate Kunert, Robyn L Stanfield, Ian A Wilson, 2005, Immunity.

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.

Bryan Briney, Ian A Wilson, Dennis R Burton, 2016, Cell reports.

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2016, Immunity.

Structure and Immune Recognition of the HIV Glycan Shield.

Ian A Wilson, I. Wilson, A. Ward, 2018, Annual review of biophysics.

Cofactor‐induced reversible folding of Flavodoxin‐4 from Lactobacillus acidophilus

Kurt Wüthrich, Adam Godzik, Ashley M Deacon, 2015, Protein science : a publication of the Protein Society.

Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.

Robyn L Stanfield, Ian A Wilson, Susan Zolla-Pazner, 2004, Structure.

Crystal Structure of Avian Aminoimidazole-4-carboxamide Ribonucleotide Transformylase in Complex with a Novel Non-folate Inhibitor Identified by Virtual Ligand Screening*

Arthur J Olson, Ian A Wilson, I. Wilson, 2004, Journal of Biological Chemistry.

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.

Ian A Wilson, I. Wilson, Kendall A. Smith, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

Ian A Wilson, Dennis R Burton, Michael Zwick, 2007, Journal of molecular biology.

A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors.

Ryan McBride, Heng Zhang, Xueyong Zhu, 2015, Cell host & microbe.

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

Robyn L Stanfield, Ian A Wilson, Dennis R Burton, 2015, Immunity.

The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.

Kenji Yoshida, Ian A Wilson, I. Wilson, 2010, The Journal of clinical investigation.

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.

James C Paulson, Pascal Poignard, Ian A Wilson, 2014, Immunity.

Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses.

Steven M. Johnson, Ian A Wilson, I. Wilson, 2010, Current opinion in structural biology.

Supine Orientation of a Murine MHC Class I Molecule on the Membrane Bilayer

Ian A Wilson, I. Wilson, J. Luz, 2004, Current Biology.

Crystal structure of a putative NADPH‐dependent oxidoreductase (GI: 18204011) from mouse at 2.10 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2004, Proteins.

HIV vaccine design and the neutralizing antibody problem

Wayne C Koff, Ian A Wilson, Dennis R Burton, 2004, Nature Immunology.

Structural origins of efficient proton abstraction from carbon by a catalytic antibody.

Donald Hilvert, Ian A Wilson, I. Wilson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020

Malik Peiris, Ian A Wilson, Kathy Leung, 2020, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities.

James C Paulson, Ian A Wilson, James Stevens, 2006, Journal of molecular biology.