Albert J Kooistra

From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands.

Chris de Graaf, Rob Leurs, Iwan J P de Esch, 2013, Methods in enzymology.

3D‐e‐Chem: Structural Cheminformatics Workflows for Computer‐Aided Drug Discovery

Stefan Verhoeven, Ross McGuire, Márton Vass, 2018, ChemMedChem.

A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?

Stefan Verhoeven, Márton Vass, David E. Gloriam, 2018, Methods in molecular biology.

Molecular interaction fingerprint approaches for GPCR drug discovery.

Tina Ritschel, Márton Vass, Chris de Graaf, 2016, Current opinion in pharmacology.

From three-dimensional GPCR structure to rational ligand discovery.

Chris de Graaf, Rob Leurs, Iwan J P de Esch, 2014, Advances in experimental medicine and biology.

Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.

Saskia Nijmeijer, Chris de Graaf, Rob Leurs, 2011, Journal of medicinal chemistry.

Discovery of novel Trypanosoma brucei phosphodiesterase B1 inhibitors by virtual screening against the unliganded TbrPDEB1 crystal structure.

Chris de Graaf, Rob Leurs, Iwan J P de Esch, 2013, Journal of medicinal chemistry.

Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology

Rob Leurs, Iwan J P de Esch, Albert J Kooistra, 2018, Journal of the American Chemical Society.

Small and colorful stones make beautiful mosaics: fragment-based chemogenomics.

Saskia Nijmeijer, Chris de Graaf, Rob Leurs, 2013, Drug Discovery Today.